Management of Coronavirus Disease 2019 Patients With Lung Cancer: Experience From a Thoracic Oncology Center

Background: Cancer patients appear to be at a higher risk of complications from coronavirus disease 2019 (COVID-19). Specific data related to lung cancer (LC) patient management, active treatment, and/or recent diagnosis are still very limited. Here, we aimed to investigate the clinical presentation, baseline features, and clinical outcomes of LC patients with COVID-19. Methods: A retrospective case study was performed at Centro Hospitalar Universitário de São Joao, a tertiary hospital in the North of Portugal. Data from LC patients diagnosed with COVID-19 were collected during the first 10 months of the COVID-19 pandemic (March 2020–January 2021). Results: Twenty-eight patients with active LC were diagnosed with COVID-19, being adenocarcinoma the most common histological type present (n = 13, 46.4%). Sixteen patients had metastatic stage IV LC (61.5%). Twenty-five patients (89.3%) had relevant comorbidities including hypertension (39.3%) and chronic obstructive pulmonary disease (32.1%). For patients undergoing antineoplastic treatment, the median time from the last chemotherapy administration to COVID-19 diagnosis was of 16 days (interquartile range = 13–41 days). Half of patients were previously on corticosteroid therapy. Twenty patients (71.4%) needed hospitalization, 18 received oxygen therapy (64.3%), 3 (10.7%) of them received high-flow nasal cannula with good tolerability, and 1 (3.6%) needed non-invasive ventilation. Hydroxychloroquine and antibiotics were given to 4 (14.3%) and 12 (42.9%) patients, respectively. Seven patients (25%) died at a median time of 5 days following COVID-19 diagnosis. Conclusion: This is one of the first studies reporting the adverse outcomes associated with COVID-19 in LC patients at same time that adds evidence regarding the need to create protocols and guidelines to reduce the infection risk in such patients.NC-M acknowledges the Portuguese Foundation for Science and Technology under the Horizon 2020 Program (PTDC/PSI-GER/28076/2017)

Establishing a governance threshold in small-scale fisheries to achieve sustainability

The lack of effective governance is a major concern in small-scale fisheries. The implementation of governance that encompasses the three pillars of sustainability (social, economic, and ecological) is still a worldwide challenge. We examined nine stalked barnacle fisheries (Pollicipes pollicipes) across Southwest Europe to better understand the relationship between governance elements and sustainability. Our results show that nested spatial scales of management, the access structure, co- management, and fisher’s participation in monitoring and surveillance promote sustainability. However, it is not the mere presence of these elements but their level of implementation that drives sustainability. Efforts should be placed in the accomplishment of a minimum combination of local scales of management, access rights through individual quotas, instructive-consultative co- management and functional participation. Surpassing this threshold in future governance structures will start to adequately promote social, economic and ecologically sustainability in small-scale fisheries

Cultivo do algodão colorido orgânico na região Semi-Árida do Nordeste Brasileiro.

bitstream/CNPA-2009-09/22235/1/DOC204.pd

Estratégias de manejo de solos em sistema agroflorestal em lote da reforma agrária.

Resumo: Sistemas Agroflorestais - sistemas embasados pelos princípios da agroecologia, o manejo dos solos deve levar em consideração a ciclagem de nutrientes, o teor de matéria orgânica e o equilíbrio entre os componentes vivos e não vivos do solo. Este artigo busca resgatar as estratégias utilizadas por um agricultor que trabalha com sistemas agroflorestais há 4 anos, evidenciando o manejo da biomassa, as espécies escolhidas, os motivos, a época de plantio e capina e os resultados observados por ele. A propriedade esta situada no Assentamento Sepé Tiaraju, localizado na região de Ribeirão Preto, SP, que constitui-se o primeiro assentamento ecológico do Estado de São Paulo. O manejo da biomassa é a principal estratégia de uso, manejo e conservação de solo para o sistema agroflorestal em estudo, o qual é caracterizado como sucessional e bastante biodiverso. As principais plantas utilizadas são: urucum (Bixa orellana), bananeira (Musa sp), mamona (Ricinus communis) e as leguminosas como o feijão de porco (Canavalia ensiformis), crotalarias (Crotalaria sp), feijão guandu (Cajanus cajan) e fedegoso (Cassia spectabilis). Vê-se que o agricultor tende a retirar do sistema as gramíneas, substituindo-as por plantas de mais fácil manejo como as leguminosas, caracterizando mudanças nas condições físicas, químicas e biológicas do solo que são descritas na bibliografia cientifica. Abstract: Agroforestry - systems based in the principles of agroecology, soil management should take into consideration the cycling of nutrients, organic matter content and balance between living and nonliving components of soil. This article seeks to rescue the strategies used by one farmer that work with agroforestry systems for 4 years, emphasizing the management of biomass, the species chosen, the reasons, the time of planting and weeding, and the results observed by owner This farm is located the Sepé Tiarauú settlement, in Ribeirão Preto, SP, which constitutes in the first ecological settlement in state of São Paulo. The management of biomass corresponds to the main strategy use, management and soil conservation in agroforestry system in study, which is characterized as successional and highly biodiverse. The main plants components used are: ?urucum? (Bixa orellana), banana (Musa sp), castobean (Ricinus communis) and legumes like ?feijão de porco? (Canavalia ensiformis), Crotalaria (Crotalaria sp), pigeon pea (Cajanus cajan) and ?fedegoso? (Cassia spectabilis). It is seen that the farmer tends to put the grass out of the system, replacing them with plants easier to work as Leguminosae family, featuring changes in physical, chemical and biological conditions of soil

Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and other constituents (3.3%). Bicyclogermacrene was its major compound (39.8%) followed by other sesquiterpenes. Most of the monoterpenes were in low concentration (<1%). Only &#946;-pinene and pseudolimonene presented the highest level of 1.6%. The volatile oil presented anti-leishmanial and trypanocidal activity against promastigotes of four species of Leishmania and trypomastigotes of Trypanosoma cruzi, showing to be more active against Leishmania (L.) chagasi (IC50 39.93 µ g/mL) (95% CI 28.00-56.95 µ g/mL)

Chemical constituents of the volatile oil from leaves of Annona coriacea and in vitro antiprotozoal activity

The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and other constituents (3.3%). Bicyclogermacrene was its major compound (39.8%) followed by other sesquiterpenes. Most of the monoterpenes were in low concentration (<1%). Only &#946;-pinene and pseudolimonene presented the highest level of 1.6%. The volatile oil presented anti-leishmanial and trypanocidal activity against promastigotes of four species of Leishmania and trypomastigotes of Trypanosoma cruzi, showing to be more active against Leishmania (L.) chagasi (IC50 39.93 µ g/mL) (95% CI 28.00-56.95 µ g/mL).21

Chemical constituents of the volatile oil from leaves of annona coriacea and in vitro antiprotozoal activity

The essential oil of the leaves from Annona coriacea Mart., Annonaceae, was extracted by hydrodistillation in a Clevenger apparatus and analyzed by GC/MS and GC/FID. The oil yield was 0.05% m/m. Sixty compounds were identified, in a complex mixture of sesquiterpenes (76.7%), monoterpenes (20.0%) and other constituents (3.3%). Bicyclogermacrene was its major compound (39.8%) followed by other sesquiterpenes. Most of the monoterpenes were in low concentration (<1%). Only β-pinene and pseudolimonene presented the highest level of 1.6%. The volatile oil presented anti-leishmanial and trypanocidal activity against promastigotes of four species of Leishmania and trypomastigotes of Trypanosoma cruzi, showing to be more active against Leishmania (L.) chagasi (IC50 39.93 µ g/mL) (95% CI 28.00-56.95 µ g/mL)2113340COORDENAÇÃO DE APERFEIÇOAMENTO DE PESSOAL DE NÍVEL SUPERIOR - CAPESFUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO - FAPESPSem informaçãoSem informaçã