The fast light of CsI(Na) crystals

The responds of different common alkali halide crystals to alpha-rays and gamma-rays are tested in our research. It is found that only CsI(Na) crystals have significantly different waveforms between alpha and gamma scintillations, while others have not this phenomena. It is suggested that the fast light of CsI(Na) crystals arises from the recombination of free electrons with self-trapped holes of the host crystal CsI. Self-absorption limits the emission of fast light of CsI(Tl) and NaI(Tl) crystals.Comment: 5 pages, 11 figures Submit to Chinese Physics

Marrow Adipose Tissue: Its Origin, Function, and Regulation in Bone Remodeling and Regeneration

Marrow adipose tissue (MAT) is a unique fat depot in the bone marrow and exhibits close relationship with hematopoiesis and bone homeostasis. MAT is distinct from peripheral adipose tissue in respect of its heterogeneous origin, site-specific distribution, and complex and perplexing function. Though MAT is indicated to function in hematopoiesis, skeletal remodeling, and energy metabolism, its explicit characterization still requires further research. In this review, we highlight recent advancement made in MAT regarding the origin and distribution of MAT, the local interaction with bone homeostasis and hematopoietic niche, the systemic endocrine regulation of metabolism, and MAT-based strategies to enhance bone formation

Thermal Regulation of Coastal Urban Forest Based on ENVI-Met Model—A Case Study in Qinhuangdao, China

Urban forests can improve human comfort by improving the near-surface microclimate. Exploring the microclimate characteristics of urban forests and their impact on human comfort is particularly important to improve the urban thermal environment through scientific urban forest design. Since most previous studies were conducted under typical inland urban climates and little is known about the thermal regulation services of coastal urban forests, this study field measured the thermal surface radiation temperature of 16 open spaces in the urban forest site in Qinhuangdao. Then the ENVI-met software was used to simulate and analyze the microclimate characteristics before and after the park’s building-up, and compare the differences in the human comfort index in different scenarios. Results indicated that: (1) Vegetation have a significant cooling effect on surrounding environment. The farther away from vegetation area, the higher the average surface temperature. (2) Water bodies have the best cooling and humidifying effect on the 9–18 m surrounding environment with the best human comfort index. (3) In summer, air temperature in park decreased by 0.4~1.4 °C, and the relative humidity increased by 0.07~2.81%. (4) After the park’s built-up, the average human comfort index was optimized by 0.02~1.87. Arranging the leisure open space around the water bodies and forest edge space of the deciduous broad-leaved forest could improve human comfort. This research is expected to provide a scientific basis and planning inspiration for the construction of coastal urban forests in the same latitude area

Thermal Regulation of Coastal Urban Forest Based on ENVI-Met Model—A Case Study in Qinhuangdao, China

Urban forests can improve human comfort by improving the near-surface microclimate. Exploring the microclimate characteristics of urban forests and their impact on human comfort is particularly important to improve the urban thermal environment through scientific urban forest design. Since most previous studies were conducted under typical inland urban climates and little is known about the thermal regulation services of coastal urban forests, this study field measured the thermal surface radiation temperature of 16 open spaces in the urban forest site in Qinhuangdao. Then the ENVI-met software was used to simulate and analyze the microclimate characteristics before and after the park’s building-up, and compare the differences in the human comfort index in different scenarios. Results indicated that: (1) Vegetation have a significant cooling effect on surrounding environment. The farther away from vegetation area, the higher the average surface temperature. (2) Water bodies have the best cooling and humidifying effect on the 9–18 m surrounding environment with the best human comfort index. (3) In summer, air temperature in park decreased by 0.4~1.4 °C, and the relative humidity increased by 0.07~2.81%. (4) After the park’s built-up, the average human comfort index was optimized by 0.02~1.87. Arranging the leisure open space around the water bodies and forest edge space of the deciduous broad-leaved forest could improve human comfort. This research is expected to provide a scientific basis and planning inspiration for the construction of coastal urban forests in the same latitude area

CHD7 Regulates Osteogenic Differentiation of Human Dental Follicle Cells via PTH1R Signaling

Chromodomain helicase DNA-binding protein 7 (CHD7) is an ATP-dependent chromatin remodeling enzyme, functioning as chromatin reader to conduct epigenetic modification. Its effect on osteogenic differentiation of human dental follicle cells (hDFCs) remains unclear. Here, we show the CHD7 expression increases with osteogenic differentiation. The knockdown of CHD7 impairs the osteogenic ability of hDFCs, characterized by reduced alkaline phosphatase activity and mineralization, and the decreased expression of osteogenesis-related genes. Conversely, the CHD7 overexpression enhances the osteogenic differentiation of hDFCs. Mechanically, RNA-seq analyses revealed the downregulated enrichment of PTH (parathyroid hormone)/PTH1R (parathyroid hormone receptor-1) signaling pathway after CHD7 knockdown. We found the expression of PTH1R positively correlates with CHD7. Importantly, the overexpression of PTH1R in CHD7-knockdown hDFCs partially rescued the impaired osteogenic differentiation. Our research demonstrates that CHD7 regulates the osteogenic differentiation of hDFCs by regulating the transcription of PTH1R

Determination of Methamphetamine by High-Performance Liquid Chromatography in Odor-Adsorbent Material Used for Training Drug-Detection Animals

The objective of the present report was to develop and validate a simple, sensitive, and selective analytical method for the determination of methamphetamine in an odor-adsorbent material (gauze) which was used to improve and standardize the training method used for drug-detection animals. High-performance liquid chromatography (HPLC) was performed using a Spherisorb ODS2 C18 column (200 mm × 4.6 mm, 5 μm), with a mobile phase consisting of a 0.25% methanol/triethylamine aqueous solution (V:V = 20:80), the pH of which was adjusted to 3.1 using glacial acetic acid, at a flow rate of 1.0 mL/min. The column temperature was 25 °C, and the detection of the analytes was performed at a wavelength of 260 nm. Methamphetamine showed good linearity (R2 = 0.9999) in the range of 4.2~83.2 mg/mL. The stability of the test material was good over 24 h. The precision of the method was good, with an average spiked recovery of 86.2% and an RSD of 2.9%. The methamphetamine content in the gauze sample was determined to be 7.8 ± 2.2 μg/sample. A high-performance liquid chromatography (HPLC) method was optimized and validated for the determination of methamphetamine in adsorbent materials (gauze). Validation data in terms of specificity, linearity, the limit of detection and the limit of quantification, reproducibility, precision, stability, and recovery indicated that the method is suitable for the routine analysis of methamphetamine in adsorbent materials (gauze) and provided a basis for training drug-detection animals