26 research outputs found
Fatigue reliability assessment of small sample excavator working devices based on Bootstrap method
To evaluate the fatigue reliability of the excavator working device, the fatigue tests of 2 sets of moving arm and bucket rod of medium-sized excavators with self-weight of 26000 kg were carried out. The virtual augmented sample method (VASM) combined with Bootstrap method was used to analyze the reliability of the excavator working device under extreme small samples, and the interval and point estimations of life parameters were obtained. Based on the lognormal distribution of the excavator working device, the reliability evaluation model of the excavator working device was esTablelished, and reliability indexes, such as reliability function, failure distribution function, inefficiency function, reliable life and so on, were obtained. And the results of fatigue safety life under different confidence and reliability were calculated. The evaluation results show that the average failure time of the excavator working device is 5885 hours under the confidence of 75%, which provides an important reference for the design, the safety inspection and maintenance decision of the excavator working device
Simulation of High Conversion Efficiency and Open-circuit Voltages Of {\alpha}-si/poly-silicon Solar Cell
The P+ {\alpha}-Si /N+ polycrystalline solar cell is molded using the AMPS-1D
device simulator to explore the new high efficiency thin film poly-silicon
solar cell. In order to analyze the characteristics of this device and the
thickness of N+ poly-silicon, we consider the impurity concentration in the N+
poly-silicon layer and the work function of transparent conductive oxide (TCO)
in front contact in the calculation. The thickness of N+ poly-silicon has
little impact on the device when the thickness varies from 20 {\mu}m to 300
{\mu}m. The effects of impurity concentration in polycrystalline are analyzed.
The conclusion is drawn that the open-circuit voltage (Voc) of P+ {\alpha}-Si
/N+ polycrystalline solar cell is very high, reaching 752 mV, and the
conversion efficiency reaches 9.44%. Therefore, based on the above optimum
parameters the study on the device formed by P+ {\alpha}-Si/N+ poly-silicon is
significant in exploring the high efficiency poly-silicon solar cell.Comment: 8 pages 6figures, 1 table
Single Crystalline Cadmium Sulfide Nanowires with Branched Structure
In this article, we report the synthesis of branched single crystal CdS nanowires. This branched CdS nanostructure is prepared by a simple surfactant-directing method, which is of particular interest as it uses readily available reagents and provides a convenient route to high-yield single crystal nanowires but with branched shape. These branched nanowires have an average diameter of about 40 nm and length up to several micrometers. A possible mechanism has been proposed and the addition of surfactant dodecylthiol into the two mixed-solvents would play an importance effect on the structure of the product. Based on the mechanism, by controlling the synthesis conditions, such as the ratios between the surfactant, inorganic solvent, and organic solvent, other kinds of nanostructures based on CdS nanowires were also prepared. Photoluminescence (PL) measurement reveals that the branched CdS nanowires have a strong emission at about 700 nm which might be due to its special structure
Special electronic structures and quantum conduction of B/P co-doping carbon nanotubes under electric field using the first principle
Boron (B)/phosphorus (P) doped single wall carbon nanotubes (B-PSWNTs) are
studied by using the First- Principle method based on density function theory
(DFT). Mayer bond order, band structure, electrons density and density of
states are calculated. It concludes that the B-PSWNTs have special band
structure which is quite different from BN nanotubes, and that metallic carbon
nanotubes will be converted to semiconductor due to boron/phosphorus co-doping
which breaks the symmetrical structure. The bonding forms in B-PSWNTs are
investigated in detail. Besides, Mulliken charge population and the quantum
conductance are also calculated to study the quantum transport characteristics
of B-PSWNT hetero-junction. It is found that the position of p-n junction in
this hetero-junction will be changed as the applied electric field increase and
it performs the characteristics of diode.Comment: 11 pages, 6 fiugres, 2 table
Sequence variations in DNA repair gene XPC is associated with lung cancer risk in a Chinese population: a case-control study
<p>Abstract</p> <p>Background</p> <p>The nucleotide excision repair (NER) protein, xeroderma pigmentosum C (XPC), participates in recognizing DNA lesions and initiating DNA repair in response to DNA damage. Because mutations in <it>XPC </it>cause a high risk of cancer in XP patients, we hypothesized that inherited sequence variations in <it>XPC </it>may alter DNA repair and thus susceptibility to cancer.</p> <p>Methods</p> <p>In this hospital-based case-control study, we investigated five <it>XPC </it>tagging, common single nucleotide polymorphisms (tagging SNPs) in 1,010 patients with newly diagnosed lung cancer and 1,011 matched cancer free controls in a Chinese population.</p> <p>Results</p> <p>In individual tagging SNP analysis, we found that rs3731055<it>AG+AA </it>variant genotypes were associated with a significantly decreased risk of lung adenocarcinoma [adjusted odds ratio (OR), 0.71; 95% confidence interval (CI), 0.56–0.90] but an increased risk of small cell carcinomas [adjusted OR, 1.79; 95% CI, 1.05–3.07]. Furthermore, we found that haplotype <it>ACCCA </it>was associated with a decreased risk of lung adenocarcinoma [OR, 0.78; 95% CI, 0.62–0.97] but an increased risk of small cell carcinomas [OR, 1.68; 95% CI, 1.04–2.71], which reflected the presence of rs3731055<it>A </it>allele in this haplotype. Further stratified analysis revealed that the protective effect of rs3731055<it>AG+AA </it>on risk of lung adenocarcinoma was more evident among young subjects (age ≤ 60) and never smokers.</p> <p>Conclusion</p> <p>These results suggest that inherited sequence variations in <it>XPC </it>may modulate risk of lung cancer, especially lung adenocarcinoma, in Chinese populations. However, these findings need to be verified in larger confirmatory studies with more comprehensively selected tagging SNPs.</p
Shortened Telomere Length Is Associated with Increased Risk of Cancer: A Meta-Analysis
BACKGROUND: Telomeres play a key role in the maintenance of chromosome integrity and stability, and telomere shortening is involved in initiation and progression of malignancies. A series of epidemiological studies have examined the association between shortened telomeres and risk of cancers, but the findings remain conflicting. METHODS: A dataset composed of 11,255 cases and 13,101 controls from 21 publications was included in a meta-analysis to evaluate the association between overall cancer risk or cancer-specific risk and the relative telomere length. Heterogeneity among studies and their publication bias were further assessed by the χ(2)-based Q statistic test and Egger's test, respectively. RESULTS: The results showed that shorter telomeres were significantly associated with cancer risk (OR = 1.35, 95% CI = 1.14-1.60), compared with longer telomeres. In the stratified analysis by tumor type, the association remained significant in subgroups of bladder cancer (OR = 1.84, 95% CI = 1.38-2.44), lung cancer (OR = 2.39, 95% CI = 1.18-4.88), smoking-related cancers (OR = 2.25, 95% CI = 1.83-2.78), cancers in the digestive system (OR = 1.69, 95% CI = 1.53-1.87) and the urogenital system (OR = 1.73, 95% CI = 1.12-2.67). Furthermore, the results also indicated that the association between the relative telomere length and overall cancer risk was statistically significant in studies of Caucasian subjects, Asian subjects, retrospective designs, hospital-based controls and smaller sample sizes. Funnel plot and Egger's test suggested that there was no publication bias in the current meta-analysis (P = 0.532). CONCLUSIONS: The results of this meta-analysis suggest that the presence of shortened telomeres may be a marker for susceptibility to human cancer, but single larger, well-design prospective studies are warranted to confirm these findings