SINONASAL VERRUCOUS CARCINOMA Case series and review of literature

Verrucous carcinoma is a low grade malignancy and is a variant of squamous cell carcinoma. It is a rare tumour of the Sino nasal tract. The neoplasm occurs in older people usually in the seventh or eighth decade of life. Our cases were sinonasal in origin and patients affected were young.

Understanding competitiveness through life experiences – A strategy-as-practice approach

Practitioners learn and enact typical ways of thinking, understanding and viewing (interpreting) things in their surroundings (fields). The paper argues that by viewing competitiveness as something done by people and not a deliberate-emergent process has the potential to provide a fresh insight as to why competitive advantage is difficult to attain, maintain and plan. Therefore, it is advocated that the nature of competitiveness be explored through the practice theory lens. It is further suggested that due to the reflexive nature of practice theory, this approach allows investigation of the network of social practices, thus bridging the understanding of how social structures and human agency link together to clarify why people do what they do. In translating Bourdieu's concepts of habitus and reflexivity the research has captured the layered intersubjective and interdependent nature of (12 practitioner interviews) becoming competitive. By doing so, the intimate understanding of the way in which practitioners organise, produce and legitimise competitiveness is captured

An Alternative Proposal of Justice: Muslim Women Activists and Socio-Legal Realities in India

In India, with the change of political leadership at the center, the sanctity of religion- based Muslim family law has been contested. This has led to the development of a new socio-political discourse which is influenced and shaped by the basic feminist ideals of equal rights for women. In this discourse, Muslim women are portrayed as necessarily suffering from unjust family laws and needing immediate cover and protection from the secular state. In the light of the judicial reform which makes the practice of instant divorce through ‘triple talaq’ among Muslims a punishable offence, this article discusses that for Muslim women the domain of law is liminal and they choose between multiple legal forums to increase their access to justice. It explores how Muslim women approach different alternative forums, and in what ways Muslim women activists are creating an opportunity for the distressed women to resolve their marital disputes more efficiently. Such an examination provides important insights into how Muslim women’s rights activists undertake their pursuit of justice within a complex, legally pluralistic landscape in the area of Muslim family law in India

Making competitiveness more meaningful – A practice approach

Policy-makers, politicians and practitioners over the past few years have based the narrative of competitiveness around the idea of ‘rebalancing the economy’. This entails viewing competitiveness as a rational process (through the Porterian lens) and identifies strategies from a top-down perspective. However, there is generally a lack of understanding of how competitiveness is practiced from the bottom-up. Therefore, this study adopts a practice-based perspective to investigate competitiveness from a practitioner’s standpoint. In this paper, Bourdieu’s habitus and reflexivity is used along with Maclean, Harvey and Chia’s notion of life history storytelling through the lens of sensemaking and legitimacy. From a constructivist perspective data was analysed using thematic analysis, codes generated and inferences made. The main contribution is that the reflexive practitioners’ past experiences shape existing practices and perceptions of competitiveness

Bottoms up! – understanding competitiveness through the practice lens

Competitiveness policy has been firm-centred, standardised, incentive-based and state driven. In other words, a top down approach to competitiveness policy is been applied. This paper attempts to take a bottoms-up approach to understanding competitiveness policy. Bourdieu’s habitus and reflexivity is used along with Maclean, Harvey and Chia’s notion of life-history storytelling through the lens of sensemaking and legitimacy. The research employs a constructivist perspective to collect and analyse qualitative evidence from practitioners’ will benefit the understanding of how competitiveness is actually played out in real life. The main contributions are that reflexive practitioner’s lived experiences shaped existing practices and opinions of competitiveness. Individual practitioners when practicing strategy in their respective fields have different competitive thresholds. The struggle of becoming a competitive practitioner has bearings on being a competitive practitioner. The struggles behind becoming what they are justify the rationality behind the passive adoption of top-down policy. Three distinct threshold of competitiveness are presented: survival, progressive and strive

MicroRNA profiling of tomato leaf curl new delhi virus (tolcndv) infected tomato leaves indicates that deregulation of mir159/319 and mir172 might be linked with leaf curl disease

Background: Tomato leaf curl virus (ToLCV), a constituent of the genus Begomovirus, infects tomato and other plants with a hallmark disease symptom of upward leaf curling. Since microRNAs (miRs) are known to control plants developmental processes, we evaluated the roles of miRNAs in Tomato leaf curl New Delhi virus (ToLCNDV) induced leaf curling. Results: Microarray analyses of miRNAs, isolated from the leaves of both healthy and ToLCNDV agroinfected tomato cv Pusa Ruby, revealed that ToLCNDV infection significantly deregulated various miRNAs representing ~13 different conserved families (e.g., miR319, miR172, etc.). The precursors of these miRNAs showed similar deregulated patterns, indicating that the transcription regulation of respective miRNA genes was perhaps the cause of deregulation. The expression levels of the miRNA-targeted genes were antagonistic with respect to the amount of corresponding miRNA. Such deregulation was tissue-specific in nature as no analogous misexpression was found in flowers. The accumulation of miR159/319 and miR172 was observed to increase with the days post inoculation (dpi) of ToLCNDV agroinfection in tomato cv Pusa Ruby. Similarly, these miRs were also induced in ToLCNDV agroinfected tomato cv JK Asha and chilli plants, both exhibiting leaf curl symptoms. Our results indicate that miR159/319 and miR172 might be associated with leaf curl symptoms. This report raises the possibility of using miRNA(s) as potential signature molecules for ToLCNDV infection. Conclusions: The expression of several host miRNAs is affected in response to viral infection. The levels of the corresponding pre-miRs and the predicted targets were also deregulated. This change in miRNA expression levels was specific to leaf tissues and observed to be associated with disease progression. Thus, certain host miRs are likely indicator of viral infection and could be potentially employed to develop viral resistance strategies

Periodic gamma-ray emissions from Geminga at or = 10(12) eV

Analysis of data from an atmospheric Cerenkov telescope indicated the periodic emission of gamma rays of energy 10 to the 12th power eV, at 60.25 second period, from 2CG 195+4. The gamma ray flux at 99% confidence level is estimated to be 9.5 x 10 to 12 photons/sq cm/s

Perception, career choice and self-efficacy of UK medical students and junior doctors in urology

Introduction: there is a growing concern about the reduced clinical exposure to urology at undergraduate level in the United Kingdom. As a consequence, the competencies of junior doctors are considered inadequate. The views of these doctors in training towards urology remain under reported.Methods: a modified Delphi method was employed to construct a questionnaire. Given the rise of social media as a platform for scientific discussion, participants were recruited via a social networking site. Outcomes assessed included career preference, exposure to urology, perceived male dominance, and confidence at core procedures.Results: in total, 412 and 66 responses were collected from medical students and junior doctors, respectively. Overall, 41% of participants felt that they had received a good level of clinical exposure to urology as part of their training and 15% were considering a career in this speciality. Female students were significantly less likely to consider urology as a career option (p &lt; 0.01). Of these, 37% of the students felt confident at male catheterization and 46% of students regarded urology as a male-dominated speciality.Conclusions: urology is perceived as male dominated and is the least likely surgical speciality to be pursued as a career option according to our survey. Increased exposure to urology at the undergraduate level and dedicated workshops for core urological procedures are needed to address these challenges.</p

Design strategies and preliminary prototype for a low-cost arsenic removal system for rural Bangladesh

Researchers have invented a material called ARUBA Arsenic Removal Using Bottom Ash that effectively and affordably removes arsenic from Bangladesh groundwater. Through analysis of studies across a range of disciplines, observations, and informal interviews conducted over three trips to Bangladesh, we have applied mechanical engineering design methodology to develop eight key design strategies, which were used in the development of a lowcost, communityscale water treatment system that uses ARUBA to remove arsenic from drinking water. We have constructed, tested, and analysed a scale version of the system. Experiments have shown that the system is capable of reducing high levels of arsenic (nearly 600 ppb) to below the Bangladesh standard of 50 ppb, while remaining affordable to people living on less than US$2/day. The system could be sustainably implemented as a public-private partnership in rural Bangladesh