On-board aircraft oxygen generating system

Onboard oxygen generation equipment with minimal ground support equipment and applicable to spacecraft and submarine us

City form and well-being: what makes London neighborhoods good places to live?

What is the relationship between urban form and citizens’ well-being? In this paper, we propose a quantitative approach to help answer this question, inspired by theories developed within the fields of architecture and population health. The method extracts a rich set of metrics of urban form and well-being from openly accessible datasets. Using linear regression analysis, we identify a model which can explain 30% of the variance of well-being when applied to Greater London, UK. Outcomes of this research can inform the discussion on how to design cities which foster the wellbeing of their residents

A scalable method to quantify the relationship between urban form and socio-economic indexes

The world is undergoing a process of fast and unprecedented urbanisation. It is reported that by 2050 66% of the entire world population will live in cities. Although this phenomenon is generally considered beneficial, it is also causing housing crises and more inequality worldwide. In the past, the relationship between design features of cities and socio-economic levels of their residents has been investigated using both qualitative and quantitative methods. However, both sets of works had significant limitations as the former lacked generalizability and replicability, while the latter had a too narrow focus, since they tended to analyse single aspects of the urban environment rather than a more complex set of metrics. This might have been caused by the lack of data availability. Nowadays, though, larger and freely accessible repositories of data can be used for this purpose. In this paper, we propose a scalable method that delves deeper into the relationship between features of cities and socio-economics. The method uses openly accessible datasets to extract multiple metrics of urban form and then models the relationship between urban form and socio-economic levels through spatial regression analysis. We applied this method to the six major conurbations (i.e., London, Manchester, Birmingham, Liverpool, Leeds, and Newcastle) of the United Kingdom (UK) and found that urban form could explain up to 70% of the variance of the English official socio-economic index, the Index of Multiple Deprivation (IMD). In particular, results suggest that more deprived UK neighbourhoods are characterised by higher population density, larger portions of unbuilt land, more dead-end roads, and a more regular street pattern

Management Accountant's Role and Functions in the Enterprise Resource Planning Environment - Author's Own Research into Enterprises in Poland

This article seeks to answer whether the implementation of an ERP system has an effect on the management accountant's tasks and functions, especially in the field of performance measurement and internal reporting. The ERP impacts on the controller's role in the organization will be evaluated using field studies on six enterprises owned by multinational corporations. The question that should be asked here is whether controller's functions and tasks will also be unaffected.Celem badania jest próba odpowiedzi na pytanie czy zastosowanie zintegrowanego systemu informatycznego w przedsiębiorstwie zmienia zadania i funkcje specjalisty do spraw rachunkowości zarządczej. Na podstawie studium przypadku sześciu przedsiębiorstw będących częścią koncernów międzynarodowych zostaje dokonana ocena wpływu zastosowania ERP na rolę kontrolera w organizacji. Autor odpowiada również na pytanie czy w funkcjach i zadaniach kontrolera nie zaobserwowane zostaną zmiany w związku z implementacją ERP

Lineage-specific interface proteins match up the cell cycle and differentiation in embryo stem cells

The shortage of molecular information on cell cycle changes along embryonic stem cell (ESC) differentiation prompts an in silico approach, which may provide a novel way to identify candidate genes or mechanisms acting in coordinating the two programs. We analyzed germ layer specific gene expression changes during the cell cycle and ESC differentiation by combining four human cell cycle transcriptome profiles with thirteen in vitro human ESC differentiation studies. To detect cross-talk mechanisms we then integrated the transcriptome data that displayed differential regulation with protein interaction data. A new class of non-transcriptionally regulated genes was identified, encoding proteins which interact systematically with proteins corresponding to genes regulated during the cell cycle or cell differentiation, and which therefore can be seen as interface proteins coordinating the two programs. Functional analysis gathered insights in fate-specific candidates of interface functionalities. The non-transcriptionally regulated interface proteins were found to be highly regulated by post-translational ubiquitylation modification, which may synchronize the transition between cell proliferation and differentiation in ESCs