733 research outputs found

    A Low-Cost Dual-Band RF Power Amplifier for Wireless Communication Systems

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    This paper presents a design of a low-cost concurrent dual-band power amplifier operating at 1.8 GHz and 2.6 GHz. The design combines the signal splitting and second harmonic suppression techniques. The power amplifier aims at achieving the high-efficiency while rejecting unwanted output mixing products when operating in the dual-band mode. These advantages are obtained by using a harmonic termination technique combining with a signal splitting method. The designed amplifier is tested at both small- and large-signal performance through simulations and measurements. The designed amplifier delivers 10.2 dB Gain, 41.2 dBm Pout, and PAE of 40.2 % at 1.8 GHz and 10.1 dB Gain, 41.1 dBm Pout, and PAE of 38.7 % at 2.6 GHz. The second harmonic suppression for 1.8 GHz band is 49 dBc while the second harmonic for the 2.6 GHz is nearly total suppression. In addition, by using the proposed circuit, the unwanted mixing products can be significantly reduced improving linearity performance

    Prostate Cancer Disparities in Risk Group at Presentation and Access to Treatment for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study With Disaggregated Ethnic Groups

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    PURPOSE: We identified (1) differences in localized prostate cancer (PCa) risk group at presentation and (2) disparities in access to initial treatment for Asian American, Native Hawaiian, and Pacific Islander (AANHPI) men with PCa after controlling for sociodemographic factors. METHODS: We assessed all patients in the National Cancer Database with localized PCa with low-, intermediate-, and high-risk disease who identified as Thai, White, Asian Indian, Chinese, Vietnamese, Korean, Japanese, Filipino, Hawaiian, Pacific Islander, Laotian, Pakistani, Kampuchean, and Hmong. Multivariable logistic regression defined adjusted odds ratios (AORs) with 95% CI of (1) presenting at progressively higher risk group and (2) receiving treatment or active surveillance with intermediate- or high-risk disease, adjusting for sociodemographic and clinical factors. RESULTS: Among 980,889 men (median age 66 years), all AANHPI subgroups with the exception of Thai (AOR = 0.84 [95% CI, 0.58 to 1.21], P > .05), Asian Indian (AOR = 1.12 [95% CI, 1.00 to 1.25], P > .05), and Pakistani (AOR = 1.34 [95% CI, 0.98 to 1.83], P > .05) men had greater odds of presenting at a progressively higher PCa risk group compared with White patients (Chinese AOR = 1.18 [95% CI, 1.11 to 1.25], P < .001; Japanese AOR = 1.36 [95% CI, 1.26 to 1.47], P < .001; Filipino AOR = 1.37 [95% CI, 1.29 to 1.46], P < .001; Korean AOR = 1.32 [95% CI, 1.18 to 1.48], P < .001; Vietnamese AOR = 1.20 [95% CI, 1.07 to 1.35], P = .002; Laotian AOR = 1.60 [95% CI, 1.08 to 2.36], P = .018; Hmong AOR = 4.07 [95% CI, 1.54 to 10.81], P = .005; Kampuchean AOR = 1.55 [95% CI, 1.03 to 2.34], P = .036; Asian Indian or Pakistani AOR = 1.15 [95% CI, 1.07 to 1.24], P < .001; Native Hawaiians AOR = 1.58 [95% CI, 1.38 to 1.80], P < .001; and Pacific Islanders AOR = 1.58 [95% CI, 1.37 to 1.82], P < .001). Additionally, Japanese Americans (AOR = 1.46 [95% CI, 1.09 to 1.97], P = .013) were more likely to receive treatment compared with White patients. CONCLUSION: Our findings suggest that there are differences in PCa risk group at presentation by race or ethnicity among Asian American, Native Hawaiian, and Pacific Islander subgroups and that there exist disparities in treatment patterns. Although AANHPI are often studied as a homogenous group, heterogeneity upon subgroup disaggregation underscores the importance of further study to assess and address barriers to PCa care

    Measurement of the circular polarization in radio emission from extensive air showers confirms emission mechanisms

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    We report here on a novel analysis of the complete set of four Stokes parameters that uniquely determine the linear and/or circular polarization of the radio signal for an extensive air shower. The observed dependency of the circular polarization on azimuth angle and distance to the shower axis is a clear signature of the interfering contributions from two different radiation mechanisms, a main contribution due to a geomagnetically-induced transverse current and a secondary component due to the build-up of excess charge at the shower front. The data, as measured at LOFAR, agree very well with a calculation from first principles. This opens the possibility to use circular polarization as an investigative tool in the analysis of air shower structure, such as for the determination of atmospheric electric fields.Comment: Accepted for publication in Phys. Rev.

    Accurate ab initio spin densities

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    We present an approach for the calculation of spin density distributions for molecules that require very large active spaces for a qualitatively correct description of their electronic structure. Our approach is based on the density-matrix renormalization group (DMRG) algorithm to calculate the spin density matrix elements as basic quantity for the spatially resolved spin density distribution. The spin density matrix elements are directly determined from the second-quantized elementary operators optimized by the DMRG algorithm. As an analytic convergence criterion for the spin density distribution, we employ our recently developed sampling-reconstruction scheme [J. Chem. Phys. 2011, 134, 224101] to build an accurate complete-active-space configuration-interaction (CASCI) wave function from the optimized matrix product states. The spin density matrix elements can then also be determined as an expectation value employing the reconstructed wave function expansion. Furthermore, the explicit reconstruction of a CASCI-type wave function provides insights into chemically interesting features of the molecule under study such as the distribution of α\alpha- and β\beta-electrons in terms of Slater determinants, CI coefficients, and natural orbitals. The methodology is applied to an iron nitrosyl complex which we have identified as a challenging system for standard approaches [J. Chem. Theory Comput. 2011, 7, 2740].Comment: 37 pages, 13 figure

    Enhanced Near-Infrared Fluorescent Sensing Using Metal-Dielectric-Metal Plasmonic Array

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    This work presents a numerical study of metal-dielectric-metal (MDM) plasmonic structure used to enhance a near-infrared fluorescent sensor. The MDM plasmonic structure consists of silver (Ag) subwavelength disk arrays on a thin silica (SiO2) spacing layer and 100-nm-thick-Ag film on a silicon (Si) substrate. The MDM plasmonic arrays with various structural parameters are designed and numerically investigated using the finite-difference time-domain (FDTD) method. Results show that the optical properties of designed structures are slightly dependent on the height of the Ag disk and strongly dependent on the Ag disk diameter and SiO2 thickness. In the near-infrared wavelength range, the proposed MDM plasmonic array has low ohmic loss and shows the high fluorescent emitting enhancement and directivity of about 16 times and 625.0, respectively, thus making MDM plasmonic array an alternative approach for near-infrared fluorescence bioimaging and biosensing devices

    Mechanical stretch and shear flow induced reorganization and recruitment of fibronectin in fibroblasts

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    It was our objective to study the role of mechanical stimulation on fibronectin (FN) reorganization and recruitment by exposing fibroblasts to shear fluid flow and equibiaxial stretch. Mechanical stimulation was also combined with a Rho inhibitor to probe their coupled effects on FN. Mechanically stimulated cells revealed a localization of FN around the cell periphery as well as an increase in FN fibril formation. Mechanical stimulation coupled with chemical stimulation also revealed an increase in FN fibrils around the cell periphery. Complimentary to this, fibroblasts exposed to fluid shear stress structurally rearranged pre-coated surface FN, but unstimulated and stretched cells did not. These results show that mechanical stimulation directly affected FN reorganization and recruitment, despite perturbation by chemical stimulation. Our findings will help elucidate the mechanisms of FN biosynthesis and organization by furthering the link of the role of mechanics with FN
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