Structural features of uranyl acrylate complexes with s-, p-, and d-monovalent metals

A series of uranyl acrylate complexes with s-, p-, and d- monovalent cations (Li, Na, Tl, and Ag) was synthesized and characterized by single crystal X-ray diffraction and IR spectroscopy. We demonstrated that the nature of the monovalent cation strongly affects the composition and crystal structure of an uranyl acrylate. Li[UO2(acr)3]·H2O (1, acr=CH2CHCOO−) crystallizes in the tetragonal crystal system and is built of chains which are connected through hydrogen bonding. The presence of an acrylic acid dimer in the reaction results in the monoclinic compound Na3[UO2(acr)3][UO2(acr)2.5(CH2CHCOOCH2CH2COO)0.5]2·5H2O (2), in which the acrylic dimer shares a position with both the acrylate anion and a water molecule. Tl[UO2(acr)3] (3) exists as two polymorphs and crystallizes in either P-1 (3a) or P213 (3b) space groups. The polymorphs differ in the dimensionality, 2D for 3a and 3D for 3b, and density. Ag2[UO2(NO3)2(acr)2]·2Hacr (4) is the first example of the Ag atom coordination to the acrylate anion through the vinyl group. In 4, the Ag–C bonds enhances the connectivity of the trinuclear [Ag2UO2(acr)2(Hacr)2(NO3)2] clusters into a layered coordination polymer. A detailed structural study of the obtained compounds was performed using Voronoi-Dirichlet tessellation

The Role of Extracellular Matrix in Skin Wound Healing

Impaired wound healing is one of the unsolved problems of modern medicine, affecting patients’ quality of life and causing serious economic losses. Impaired wound healing can manifest itself in the form of chronic skin wounds or hypertrophic scars. Research on the biology and physiology of skin wound healing disorders is actively continuing, but, unfortunately, a single understanding has not been developed. The attention of clinicians to the biological and physiological aspects of wound healing in the skin is necessary for the search for new and effective methods of prevention and treatment of its consequences. In addition, it is important to update knowledge about genetic and non-genetic factors predisposing to impaired wound healing in order to identify risk levels and develop personalized strategies for managing such patients. Wound healing is a very complex process involving several overlapping stages and involving many factors. This thematic review focuses on the extracellular matrix of the skin, in particular its role in wound healing. The authors analyzed the results of fundamental research in recent years, finding promising potential for their transition into real clinical practice

Electronic Structure of Cesium Butyratouranylate(VI) as Derived from DFT-assisted Powder X‑ray Diffraction Data

Investigation of chemical bonding and electronic structure of coordination polymers that do not form high-quality single crystals requires special techniques. Here, we report the molecular and electronic structure of the first cesium butyratouranylate, Cs­[UO₂(<i>n</i>-C₃H₇COO)₃]­[UO₂(<i>n</i>-C₃H₇COO)­(OH)­(H₂O)], as obtained from DFT-assisted powder X-ray diffraction data because of the low quality of crystalline sample. The topological analysis of the charge distribution within the quantum theory of atoms-in-molecules (QTAIM) space partitioning and the distribution of electron localization function (ELF) is reported. The constancy of atomic domain of the uranium­(VI) atom at different coordination numbers (7 and 8) and the presence of three ELF maxima in equatorial plane of an uranyl cation attributed to the 6s and 6p electrons were demonstrated for the first time. Details of methodologies applied for additional verification of the correctness of powder XRD refinement (Voronoi atomic descriptors and the Morse restraints) are discussed

Electronic Structure of Cesium Butyratouranylate(VI) as Derived from DFT-assisted Powder X‑ray Diffraction Data

Investigation of chemical bonding and electronic structure of coordination polymers that do not form high-quality single crystals requires special techniques. Here, we report the molecular and electronic structure of the first cesium butyratouranylate, Cs­[UO₂(<i>n</i>-C₃H₇COO)₃]­[UO₂(<i>n</i>-C₃H₇COO)­(OH)­(H₂O)], as obtained from DFT-assisted powder X-ray diffraction data because of the low quality of crystalline sample. The topological analysis of the charge distribution within the quantum theory of atoms-in-molecules (QTAIM) space partitioning and the distribution of electron localization function (ELF) is reported. The constancy of atomic domain of the uranium­(VI) atom at different coordination numbers (7 and 8) and the presence of three ELF maxima in equatorial plane of an uranyl cation attributed to the 6s and 6p electrons were demonstrated for the first time. Details of methodologies applied for additional verification of the correctness of powder XRD refinement (Voronoi atomic descriptors and the Morse restraints) are discussed