High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F-2 alpha concentrations relative to a control high-oleic acid meal: a randomized controlled trial

Background: Eicosapentaenoic acid (EPA) plus docosahexaenoic acid (DHA) supplementation has beneficial cardiovascular effects, but postprandial influences of these individual fatty acids are unclear. Objectives: The primary objective was to determine the vascular effects of EPA + DHA compared with DHA only during postprandial lipemia relative to control high–oleic acid meals; the secondary objective was to characterize the effects of linoleic acid–enriched high-fat meals relative to the control meal. Design: We conducted a randomized, controlled, double-blind crossover trial of 4 high-fat (75-g) meals containing 1) high–oleic acid sunflower oil (HOS; control), 2) HOS + fish oil (FO; 5 g EPA and DHA), 3) HOS + algal oil (AO; 5 g DHA), and 4) high–linoleic acid sunflower oil (HLS) in 16 healthy men (aged 35–70 y) with higher than optimal fasting triacylglycerol concentrations (mean ± SD triacylglycerol, 1.9 ± 0.5 mmol/L). Results: Elevations in triacylglycerol concentration relative to baseline were slightly reduced after FO and HLS compared with the HOS control (P < 0.05). The characteristic decrease from baseline in plasma nonesterified fatty acids after a mixed meal was inhibited after AO (Δ 0–3 h, P < 0.05). HLS increased the augmentation index compared with the other test meals (P < 0.05), although the digital volume pulse–reflection index was not significantly different. Plasma 8-isoprostane F(2α) analysis revealed opposing effects of FO (increased) and AO (reduced) compared with the control (P < 0.05). No differences in nitric oxide metabolites were observed. Conclusions: These data show differential postprandial 8-isoprostane F(2α) responses to high-fat meals containing EPA + DHA–rich fish oil compared with DHA-rich AO, but these differences were not associated with consistent effects on postprandial vascular function or lipemia. More detailed analyses of polyunsaturated fatty acid–derived lipid mediators are required to determine possible divergent functional effects of single meals rich in either DHA or EPA. This trial was registered at clinicaltrials.gov as NCT01618071

A multiple-scattering approach to interatomic interactions and superradiance in inhomogeneous dielectrics

The dynamics of a collection of resonant atoms embedded inside an inhomogeneous nondispersive and lossless dielectric is described with a dipole Hamiltonian that is based on a canonical quantization theory. The dielectric is described macroscopically by a position-dependent dielectric function and the atoms as microscopic harmonic oscillators. We identify and discuss the role of several types of Green tensors that describe the spatio-temporal propagation of field operators. After integrating out the atomic degrees of freedom, a multiple-scattering formalism emerges in which an exact Lippmann-Schwinger equation for the electric field operator plays a central role. The equation describes atoms as point sources and point scatterers for light. First, single-atom properties are calculated such as position-dependent spontaneous-emission rates as well as differential cross sections for elastic scattering and for resonance fluorescence. Secondly, multi-atom processes are studied. It is shown that the medium modifies both the resonant and the static parts of the dipole-dipole interactions. These interatomic interactions may cause the atoms to scatter and emit light cooperatively. Unlike in free space, differences in position-dependent emission rates and radiative line shifts influence cooperative decay in the dielectric. As a generic example, it is shown that near a partially reflecting plane there is a sharp transition from two-atom superradiance to single-atom emission as the atomic positions are varied.Comment: 18 pages, 4 figures, to appear in Physical Review

Luminescence Spectra of Quantum Dots in Microcavities. I. Bosons

We provide a unified theory of luminescence spectra of coupled light-matter systems realized with semiconductor heterostructures in microcavities, encompassing: i) the spontaneous emission case, where the system decays from a prepared (typically pure) initial state, and ii) luminescence in the presence of a continuous, incoherent pump. While the former case has been amply discussed in the literature (albeit mainly for the case of resonance), no consideration has been given to the influence of the incoherent pump. We show how, by provoking a self-consistent quantum state, the pump considerably alters the emission spectra, even at vanishing intensities. The main outcome of our analysis is to unambiguously identify strong-coupling in situations where it appears in disguise or only seems to appear. Here, we consider bosonic matter fields, in which case fully analytical solutions can be obtained. This describes the case of quantum wells or large quantum dots, or the limit of low excitation where the average populations remain much smaller than one

Sense-giving in health care: the relationship between the HR roles of line managers and employee commitment

In this article, we examine line manager prioritisation of HR roles and the consequences for employee commitment in a health-care setting. Our analysis is based on a quantitative, multi-actor study (509 employees and 67 line managers) in four Dutch hospitals. Using sense-giving as a theoretical lens, we demonstrate that, in addition to the effects of high commitment HRM, prioritising the Employee Champion role alone and the Employee Champion and Strategic Partner roles in combination is associated with higher employee commitment. We argue that through performing roles that are evocative of deep-seated values, such as excellent patient care and concern for others, line managers can have a positive effect on staff attitudes. In a sector often beleaguered by staff turnover, exhaustion and burnout, we offer an important, empirically based framework that has the potential to improve employee commitment and, from there, enhance performance

Graduate dress code: How undergraduates are planning to use hair, clothes and make-up to smooth their transition to the workplace

This article explores the relationship between students’ identities, their ideas about professional appearance and their anticipated transition to the world of work. It is based on a series of semi-structured interviews with 13 students from a vocationally-focused university in England. It was found that participants viewed clothing and appearance as an important aspect of their transition to the workplace. They believed that, if carefully handled, their appearance could help them to fit in and satisfy the expectations of employers, although some participants anticipated that this process of fitting in might compromise their identity and values. The article addresses students’ anticipated means of handling the tension between adapting to a new environment and ‘being themselves’. It is argued that the way this process is handled is intertwined with wider facets of identity – most notably those associated with gender.The article is based on research funded by the University of Derby. © 2015 IP Publishing Ltd. ((http://www.ippublishing.com). Reproduced by permission

Endoscopic Posterior Cricoid Split with Costal Cartilage Graft: A Fifteen‐Year Experience

Objective To evaluate outcomes of the endoscopic posterior cricoid split with rib graft (EPCS/RG) procedure in the treatment of subglottic stenosis (SGS), posterior glottic stenosis (PGS), and bilateral vocal fold immobility (BVFI). Study Design Retrospective chart review. Methods Chart review of all patients who underwent EPCS/RG at a single tertiary-care facility between 1999 and 2014. Patients were grouped based on the primary indication for the procedure. Decannulation was the primary endpoint. Secondary endpoints were the number of subsequent airway procedures and length of hospitalization. Results Thirty-three patients were identified; 32 had tracheotomy. Overall decannulation rate was 65.6%. Subgroup analysis demonstrated the following decannulation rates: 53.8% for SGS, 100% for PGS, and 28.6% for BVFI. Fisher exact test found a significant difference in overall decannulation rates between groups (P = 0.002). Operation-specific decannulation rates for patients who never required an open procedure were 23% for SGS, 91.6% for PGS, and 28.6% for BVFI. This difference was also statistically significant (P = 0.001). Multivariate logistic regression analysis found prematurity had a positive correlation with decannulation that approached statistical significance (P < 0.051; odds ratio 6.1; 95% confidence interval 0.99, 37.6). The percentage of patients who underwent repeat airway procedures for the groups was 61.5% for SGS, 16.6 % for PGS, and 14.3% for BVFI. The median length of hospitalization after EPCS/RG was 3 days. Conclusion This represents the largest series of patients who have undergone EPCS/RG and demonstrates that the majority of patients can be decannulated after this procedure. Patients with PGS had the highest operation-specific decannulation rates

Is the number of Photons a Classical Invariant?

We describe an apparent puzzle in classical electrodynamics and its resolution. It is concerned with the Lorentz invariance of the classical analog of the number of photons.Comment: Revised version, 3 figure

Rotational Cooling of Polar Molecules by Stark-tuned Cavity Resonance

A general scheme for rotational cooling of diatomic heteronuclear molecules is proposed. It uses a superconducting microwave cavity to enhance the spontaneous decay via Purcell effect. Rotational cooling can be induced by sequentially tuning each rotational transition to cavity resonance, starting from the highest transition level to the lowest using an electric field. Electrostatic multipoles can be used to provide large confinement volume with essentially homogeneous background electric field.Comment: 10 pages, 6 figure

Transversality of Electromagnetic Waves in the Calculus-Based Introductory Physics Course

Introductory calculus-based physics textbooks state that electromagnetic waves are transverse and list many of their properties, but most such textbooks do not bring forth arguments why this is so. Both physical and theoretical arguments are at a level appropriate for students of courses based on such books, and could be readily used by instructors of such courses. Here, we discuss two physical arguments (based on polarization experiments and on lack of monopole electromagnetic radiation), and the full argument for the transversality of (plane) electromagnetic waves based on the integral Maxwell equations. We also show, at a level appropriate for the introductory course, why the electric and magnetic fields in a wave are in phase and the relation of their magnitudes.Comment: 10 pages, 6 figure

OSSE observations of galactic 511 keV annihilation radiation

The Oriented Scintillation Spectrometer Experiment (OSSE) on the Compton Gamma-Ray Observatory has performed several observations of the galactic plane and galactic center region to measure the distribution of galactic 511 keV positron annihilation radiation. Preliminary analysis of data collected during the observation of the galactic center region over the period 13-24 Jun. 1991, indicates the presence of a 511 keV line and positronium continuum superimposed on a power-law continuum. The line of flux was found to be (2.7 +/- 0.5) x 10(exp -4) gamma/sq cm sec, with a positronium fraction of (0.9 +/- 0.2). The 3(sigma) upper limit to daily variations in the 511 keV line flux from the mean during the observation interval is 3 x 10(exp -4) gamma/sq cm sec. If all of the observed annihilation radiation is assumed to originate from the x-ray source 1E 1740.7-2942, the corresponding 511 keV line flux would be (3.0 +/- 0.6) x 10(exp -4) gamma/sq cm sec. The 3(sigma) upper limit for 511 keV line emission from the x-ray binary GX1+4 is 6 x 10(exp -4) gamma/sq cm sec. Results from the galactic plane observations at galactic longitudes of 25 degrees (16-21 Aug. 1991) and 339 degrees (6-11 Sep. 1991) suggest that the emission is concentrated near the galactic center. The observations and the preliminary results are described