483 research outputs found
Facilitating engagement with the challenges facing families in which there may be members with special needs : positing a model for theatrical intervention
Includes bibliographical references.The purpose of the study is to investigate the manner in which performance can facilitate communication amongst family members in dealing with the challenges facing families in which there is a member with âspecial needsâ. Special needs range from problems of mental or emotional anguish, care, disability or chronic illnesses. My interest in this study is on how these special needs impact on the functioning of the family and family dynamics. Theatrical representation and audience participation is at the heart of exploring the empowering role of applied theatre to engage family members in expressing their difficulties and discussing their issues together
The financed inked individual subsidy programme for housing: the Walmer link example
The study of the Walmer Links Finance Linked Individual Subsidy (FLISP) is the response to the housing backlogs that have been experienced by the Port Elizabeth area. The ownership programme is the first of its kind in the area and has been met with scepticism, revolt and acceptance as the neighbouring township of Walmer and the nearby suburbs had mixed feelings about the project. The overall feeling and experience of the new FLISP owners far exceeds the scepticism around the project. The project also brought racial integration and improved the quality of life for the poor. It also seems as though the success of the project will be the determinant factor of whether it can rolled out to other provinces as an approach to development and poverty alleviation
A Resilient and Effective Task Scheduling Approach for Industrial Human-Robot Collaboration
Effective task scheduling in human-robot collaboration (HRC) scenarios is one of the great challenges of collaborative robotics. The shared workspace inside an industrial setting brings a lot of uncertainties that cannot be foreseen. A prior offline task scheduling strategy is ineffective in dealing with these uncertainties. In this paper, a novel online framework to achieve a resilient and reliable task schedule is presented. The framework can deal with deviations that occur during operation, different operator skills, error by the human or robot, and substitution of actors, while maintaining an efficient schedule by promoting parallel human-robot work. First, the collaborative job and the possible deviations are represented by AND/OR graphs. Subsequently, the proposed architecture chooses the most suitable path to improve the collaboration. If some failures occur, the AND/OR graph is adapted locally, allowing the collaboration to be completed. The framework is validated in an industrial assembly scenario with a Franka Emika Panda collaborative robot
Analisis program inovasi pembangunan dan pemberdayaan kewilayahan (PIPPK) di kecamatan cinambo kelurahan babakan penghulu kota bandung
Pembangunan pada hakekatnya merupakan suatu proses yang bersifat
integratif, baik dalam tataran perencanaan, pelaksanaan maupun pengendalian yang
dilakukan secara berkesinambungan dalam rangka mewujudkan kesejahteraan
masyarakat. Mengingat ruang lingkupnya yang sangat luas, kegiatan pembangunan
tidak semata-mata menjadi tanggung jawab pemerintah daerah, melainkan harus
dilakukan dan didukung oleh seluruh komponen masyarakat. Adapun
pemberdayaan adalah upaya dan proses yang dilakukan supaya masyarakat
memiliki keleluasaan dalam menentukan pilihan-pilihan dalam hidupnya yang lebih
khas dan lokal, masyarakat dapat berpartisipasi dalam berbagai kegiatan
pembangunan desa. Kecamatan Cinambo, Kelurahan Babakan Penghulu
merupakan salah satu instansi pemerintahan yang menjalankan pembangunan dan
juga pemberdayaan terhadap masyarakatnya melalui Program Inovasi
Pembangunan dan Pemberdayaan Kewilayahan (PIPPK) program ini ditujukan
untuk mencapai tujuan dan sasaran yang telah ditetapkan bersama melalui suatu
media pertanggungjawaban. Tujuan penelitian ini adalah untuk mengetahui dan
menggambarkan kondisi nyata mengenai Program Inovasi Pembangunan dan
Pemberdayaan Kewilayahan (PIPPK) serta faktor penghambat dan pendukung.
Metode penelitian yang digunakan peneliti yaitu penelitian kualitatif dengan
pendekatan deskriptif, yakni untuk memberikan gambaran secara jelas mengenai
masalah-masalah yang diteliti di Kecamatan Cinambo, Kelurahan Babakan
Penghulu. Untuk memperoleh data, peneliti melakukan wawancara, dan studi
dokumentasi/pustaka. Hasil penelitian menunjukan bahwa PIPPK (Program Inovasi
Pembangunan dan Pemberdayaan Kewilayahan) yang dilakukan Kecamatan
Cinambo Kelurahan Babakan Penghulu Kota Bandung sudah dapat dikatakan baik
karena dengan adanya program ini pembangunan dan masyarakatnya menjadi
semakin berdaya meskipun masih terdapat berbagai hambatan dalam setiap
realisasinya dan juga masih diperlukan adanya evaluasi. Selanjutnya, berdasarkan
hasil analisis dari wawancara yang menjadi kekuatan dalam Program Inovasi
Pembangunan dan Pemberdayaan Kewilayahan (PIPPK) yaitu kesesuaian peraturan
pemerintah dalam pelaksanaan program tersebut, terdapat kelemahan yaitu belum
tercapainya setiap target yang akan dilakukan, kurangnya transparansi dalam
penggunaan anggaran, keterbatasan SDM dalam pengelolaan dana PIPPK,
kurangnya keterlibatan masyarakat dalam pelaksanaan program PIPPK dan
kurangnya koordinasi antara aparat kewilayahan dengan SKPD. Kedua faktor
pendukung adanya bantuan dana sebesar 100 juta yang diberikan oleh pemerintah
untuk masing-masing LKK yang ada di Kelurahan. Ketiga, faktor penghambat
pejabat birokrasi takut sehingga mengakibatkan terhambat atau tertundanya
pencairan dana dalam pelaksanaan program tersebut
Os usos do salão de beleza : para além do consumo de estética ou sobre possibilidades de invenção de si
Na contemporaneidade, o tema consumo tem despertado interesse de estudiosos de
vĂĄrias ĂĄreas. Assim, vem sendo abordado a partir de diversas perspectivas, sejam
elas à luz do processo de produção ou marcadas pelo social. Este trabalho, a partir
dos estudos de Certeau (2008; 2009; 1995; 1982; 2011), busca compreender o
consumo como âusoâ criativo, ao apostar na potĂȘncia que tĂȘm as prĂĄticas ordinĂĄrias
dos sujeitos praticantes do cotidiano. O carĂĄter artĂstico das prĂĄticas daria ao
consumo uma dimensĂŁo inventiva, inapreensĂvel e polĂtica. Dessa forma, a pesquisa
se concentra nos consumos/ usos que sĂŁo feitos de um salĂŁo de beleza em um
bairro de classe mĂ©dia alta na cidade de VitĂłria â ES. A ideia Ă© negociar sentidos
mais amplos para a noção de consumo estético do que aqueles estereotipados que
relacionam o consumo de beleza ao supĂ©rfluo e fĂștil. A produção dos dados sinaliza
para uma diversa gama de âusosâ possĂveis do salĂŁo de beleza. Esses usos
potencializam diferentes modos de existĂȘncia, baseados no cuidado de si a partir do
cuidado com o corpo e com a saĂșde; nas relaçÔes Ă©ticas pautadas pela dimensĂŁo
estĂ©tica, e nas possibilidades de assumir estĂ©ticas âmenoresâ com linhas de escape,
e dessa forma, produzirem diferentes sentido para a noção de consumo.In the contemporaneous context, the act of consuming has been a subject of great
interest by researchers from different areas. It has been approached from diversified
perspectives, based on production process or social argument. This research,
originated from Certeauâs (2008, 2009, 1995, 1982, 2011) studies, is an attempt to
understand the act of consuming as a creative âuseâ, taking into consideration the
power of ordinary practices proper of people who perform everyday events. The
practices artistic nature would confer to the act of consuming an inventive and
political dimension. This way, this research concentrates on consumptions/uses that
are performed at a beauty parlour in a high medium social class neighborhood in
VitĂłria â ES. The objective is to negotiate wider senses, related to the notion of
esthetics consumption, than those stereotyped ideas which associate beauty
consumption to superfluous and frivolous actions. The inform data production
indicates a diverse range of possible âusesâ of the beauty parlour, which strengthens
different ways of existence, based on taking care of oneself, including body and
health issues; on the ethical relationships guided by esthetics dimension and
possibilities of assuming âminorâ esthetics with vanishing lines, allowing to produce
different meanings associated to consumption
The efficacy of three double-microencapsulation methods for preservation of probiotic bacteria
Lactic acid bacteria (LAB) are used as a probiotic alternative to antibiotics in livestock production. Microencapsulation technology is widely used for probiotic preservation. A variety of microencapsulation protocols have been proposed and compared based on chemicals and mechanical procedures. This study aimed to develop a double-encapsulated coating from alginate (1.5%) and chitosan (0.5%) by extrusion, emulsion, and spray drying methods using the LAB strains Lactobacillus plantarum strains 31F, 25F, 22F, Pediococcus pentosaceus 77F, and P. acidilactici 72N, and to monitor the basic probiotic properties of the encapsulated prototypes. The final products from each microencapsulation protocol were analysed for their appearance, probiotic properties and viable cell count. Using the spray drying method, particles smaller than 15 ÎŒm in diameter with a regular spherical shape were obtained, whereas the other methods produced larger (1.4â52 mm) and irregularly shaped microcapsules. After storage for 6 months at room temperature, the LAB viability of the spray-dried particles was the highest among the three methods. In all the LAB strains examined, the encapsulated LAB retained their probiotic properties in relation to acid-bile tolerance and antibacterial activity. This study highlights the efficacy of double-coating microencapsulation for preserving LAB properties and survival rate, and demonstrates its potential for probiotic application in livestock farms
Her2 signaling and breast cancer stem cells: The bridge behind her2-positive breast cancer aggressiveness and therapy refractoriness
HER2 overexpression/amplification occurs in 15â20% of breast cancers (BCs) and identifies a highly aggressive BC subtype. Recent clinical progress has increased the cure rates of limited-stage HER2-positive BC and significantly prolonged overall survival in patients with advanced disease; however, drug resistance and tumor recurrence remain major concerns. Therefore, there is an urgent need to increase knowledge regarding HER2 biology and implement available treatments. Cancer stem cells (CSCs) represent a subset of malignant cells capable of unlimited self-renewal and differentiation and are mainly considered to contribute to tumor onset, aggressiveness, metastasis, and treatment resistance. Seminal studies have highlighted the key role of altered HER2 signaling in the maintenance/enrichment of breast CSCs (BCSCs) and elucidated its bidirectional communication with stemness-related pathways, such as the Notch and Wingless/ÎČ-catenin cascades. d16HER2, a splice variant of full-length HER2 mRNA, has been identified as one of the most oncogenic HER2 isoform significantly implicated in tumorigenesis, epithelial-mesenchymal transition (EMT)/stemness and the response to targeted therapy. In addition, expression of a heterogeneous collection of HER2 truncated carboxy-terminal fragments (CTFs), collectively known as p95HER2, identifies a peculiar subgroup of HER2-positive BC with poor prognosis, with the p95HER2 variants being able to regulate CSC features. This review provides a comprehensive overview of the current evidence regarding HER2-/d16HER2-/p95HER2-positive BCSCs in the context of the signaling pathways governing their properties and describes the future prospects for targeting these components to achieve long-lasting tumor control
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