Analysis of Factors Affecting the Shaping of Materials in Clothing

При формообразовании костюма необходимо учитывать формовочные свойства материала, то есть его способность образовывать пространственную форму и устойчиво сохранять ее в процессе эксплуатации изделия. На способность тканей к формообразованию влияет их переплетение, волокнистый состав, структурные характеристики, физико-механические свойства, отделка и др.When shaping a suit, it is necessary to take into account the forming properties of the material, that is, its ability to form a spatial shape and stably maintain it during the operation of the product. The ability of fabrics to form is affected by their weave, fibrous composition, structural characteristics, physical and mechanical properties, finishing, etc

The 4q25/PITX2 SNP rs6817105 and Atrial Fibrillation in Uzbek Patients with Arterial Hypertension

Background: Atrial fibrillation (AF) is one of the most common cardiac arrhythmias and a major predictor of morbidity and mortality. In recent years, genome-wide association studies (GWAS) have identified common genetic variants associated with a higher risk of AF. The aim of our research was to study the possible association of the 4q25/PITX2 SNP rs6817105 with the risk of developing AF in patients with arterial hypertension (AH) in the Uzbek population. Methods and Results: The study included 142 AH (Grades 1-3; ESC/ESH, 2018) patients of Uzbek nationality who were initially diagnosed with paroxysmal form (15[10.6%]), persistent form (43[30.3%]), and permanent form of AF (84[59.1%]). The mean age of these patients was 64.8±10.9 years. AF was verified using ECG Holter monitoring. The control group (n=88) consisted of AH patients without AF with a mean age of 56.5±12.3 years. Echocardiography was carried out according to the recommendations of the American Society of Echocardiography in M- and B-modes. We genotyped SNP rs6817105 (T>C) and examined the relationships among rs6817105 genotype, clinical characteristics, and echocardiographic parameters in AH patients with AF and non-AF AH patients (controls). The rs6817105 minor C allele frequency was significantly higher in AH patients with AF than in non-AF AH patients (71.8% vs. 59.7%, P=0.007). Analysis of the multiplicative model for the rs6817105 SNP showed a significant risk of AF in the carriage of the C allele (OR=1.72, 95% CI: 1.16-2.56, P=0.007). The dominant and additive models for the rs6817105 SNP showed a significant risk of AF with the carriage of the CC+CT genotypes (OR=3.16, 95% CI: 1.37-7.27, P=0.005) and the homozygous CC genotype (OR=1.63, 95% CI: 0.95-2.81, P=0.008), respectively. The allelic distribution showed that the carriage of the C allele was dominant in permanent and persistent AF (110/68.75% vs. 50/31.25% for the T allele [(χ2=22.50, P=0.000], and 73.61% (64/74.41%) vs. 26.39% (22/25.58%) for the T allele [χ2=20.512, P=0.000], respectively). Among AH patients with paroxysmal AF, the C allele prevailed to the greatest extent: 20(90.9%) vs. 2(9.1%) for the T allele (χ2=14.727, P=0.000), indicating a significant accumulation of the C allele and CC genotype among patients with paroxysmal AF. In general, in AH patients with AF, carriers of the CC genotype, the left atrial volume index (LAVI) was significantly higher than the carriers of the CT and TT genotypes: 46.8±13.9 ml/m2 vs. 40.4±13.0 ml/m2 and 36.1±11.0 ml/m2, respectively (P=0.0083). Conclusion: Our results indicate the rs6817105 minor C allele and CC genotype are associated with the risk of developing AF in AH patients of Uzbek nationality. The highest accumulation of the rs6817105 minor C allele and CC genotype is found in paroxysmal AF. In carriers of the rs6817105 CC genotype, the LAVI was significantly larger than in carriers of the CT and TT genotypes

УЛЬТРАЗВУКОВОЕ ИССЛЕДОВАНИЕ В КОМПЛЕКСНОЙ ЛУЧЕВОЙ ДИАГНОСТИКЕ МЕТАСТАТИЧЕСКОГО ПОРАЖЕНИЯ ПАРАСТЕРНАЛЬНОГО ЛИМФАТИЧЕСКОГО КОЛЛЕКТОРА У БОЛЬНОЙ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ (КЛИНИЧЕСКИЙ СЛУЧАЙ)

Background. The parasternal lymphatic collector is an important pathway of the lymph drainage from the breast in breast cancer patients. Evaluation of parasternal lymph nodes is not available during physical examination. To date, no algorithm for diagnostic imaging of the parasternal lymphatic pathway has been developed. The presence of metastases in parasternal lymph nodes upstages the breast cancer patient to a minimum of clinical stage III disease.Case description. We present the case of breast cancer progression in a 40-year-old woman. The patient received treatment for triple-negative stage IIA breast cancer (Т2N0M0) in 2018. In August, 2019, 18-FDG PET /CT images revealed a solitary metastasis in the parasternal lymph node. Ultrasound images also showed the same lymph node assessed by PET -CT and the additional parasternal lymph node metastasis. A fine-needle aspiration biopsy of both lymph nodes confirmed the specific involvement of the parasternal lymph nodes.Conclusion. Ultrasound scans are used to assess the axillary, subclavian and supraclavicular lymphatic collectors, but there is little evidence in the literature on the use of ultrasound in the assessment of parasternal lymph nodes. Our clinical case shows the feasibility of using ultrasound in assessing the status of the parasternal of lymph nodes, as well as the feasibility of performing fine-needle aspiration biopsy by ultrasound navigation.Актуальность. Парастернальный лимфатический коллектор является важной областью регионарного лимфатического оттока у больных раком молочной железы. Оценка лимфатических узлов данной группы не доступна при физикальном обследовании. Кроме того, не разработан алгоритм лучевых методов диагностики поражения этого коллектора. При специфическом поражении лимфатических узлов этой группы стадия заболевания увеличивается до стадии iiia и первым этапом лечения рекомендуется проведение химиотерапии. Описание клинического случая. Приводим собственное наблюдение прогрессирования рака молочной железы у пациентки 40 лет. Пациентка  находится на динамическом контроле после комплексного лечения, проведенного в 2018 г. по поводу рака молочной железы, Т2N0m0, iiА стадия, тройной негативный тип. При плановом исследовании в августе 2019 г. по данным ПЭТ/КТ с 18F-ФДГ у пациентки  выявлен солитарный метастаз в парастернальный лимфатический узел. Дополнительно проведено ультразвуковое исследование, при котором выявлен  описанный при ПЭТ-КТ лимфатический узел, а также дополнительный изменённый лимфатический узел парастернальной области, произведена тонкоигольная  аспирационная биопсия обоих лимфатических узлов, по результатам которой подтверждено специфическое поражение парастернальных лимфатических узлов. Заключение. Ультразвуковая диагностика используется для оценки аксиллярного,  подлючичного и надключичного лимфатических коллекторов, однако в литературе мало данных об использовании данного метода в оценке лимфатических узлов парастернальной области. На клиническом примере показана возможность использования ультразвуковой диагностики в оценке состояния парастернальной  группы лимфатических узлов, а также возможности проведения тонкоигольной  аспирационной биопсии под УЗ-навигацией

Polarization angle swings in blazars: The case of 3C 279

© ESO, 2016.Context. Over the past few years, on several occasions, large, continuous rotations of the electric vector position angle (EVPA) of linearly polarized optical emission from blazars have been reported. These events are often coincident with high energy γ-ray flares and they have attracted considerable attention, since they could allow us to probe the magnetic field structure in the γ-ray emitting region of the jet. The flat-spectrum radio quasar 3C 279 is one of the most prominent examples showing this behaviour. Aims. Our goal is to study the observed EVPA rotations and to distinguish between a stochastic and a deterministic origin of the polarization variability. Methods. We have combined multiple data sets of R-band photometry and optical polarimetry measurements of 3C 279, yielding exceptionally well-sampled flux density and polarization curves that cover a period of 2008-2012. Several large EVPA rotations are identified in the data. We introduce a quantitative measure for the EVPA curve smoothness, which is then used to test a set of simple random walk polarization variability models against the data. Results. 3C 279 shows different polarization variation characteristics during an optical low-flux state and a flaring state. The polarization variation during the flaring state, especially the smooth ∼360° rotation of the EVPA in mid-2011, is not consistent with the tested stochastic processes. Conclusions. We conclude that, during the two different optical flux states, two different processes govern polarization variation, which is possibly a stochastic process during the low-brightness state and a deterministic process during the flaring activity

Velocity-resolved reverberation mapping of five bright Seyfert 1 galaxies

We present the first results from a reverberation-mapping campaign undertaken during the first half of 2012, with additional data on one AGN (NGC 3227) from a 2014 campaign. Our main goals are (1) to determine the black hole masses from continuum-Hβ reverberation signatures, and (2) to look for velocity-dependent time delays that might be indicators of the gross kinematics of the broad-line region. We successfully measure Hbeta time delays and black hole masses for five AGNs, four of which have previous reverberation mass measurements. The values measured here are in agreement with earlier estimates, though there is some intrinsic scatter beyond the formal measurement errors. We observe velocity dependent Hβ lags in each case, and find that the patterns have changed in the intervening five years for three AGNs that were also observed in 2007.PostprintPeer reviewe

X-RAY SPECTRAL PROPERTIES OF THE ISOLATED AGNs: NGC 1050, NGC 2989, ESO 317-038, ESO 438-009

We have analyzed the spectral data obtained by XMM-Newton, Swift, Chandra, and INTEGRAL space observatories for several isolated AGNs from 2MIG catalogue, for which the available X-ray data were accessed. Among these objects were CGCG 179-005, NGC 6300, NGC 1050, NGC 2989, WKK 3050, ESO 438-009, and ESO 317-038. We determined corresponding spectral models and values of their parameters (spectral index, intrinsic absorption etc.). X-ray spectra for bright galaxies, NGC 6300 and Circinus, were analyzed up to 250 keV and their characteristics of emission features were determined in 6-7 keV range. We present the results for NGC 1050, NGC 2989, ESO 317-038, and ESO 438-009, for which their spectral parameters were obtained for the first time.We have analyzed the spectral data obtained by XMM-Newton, Swift, Chandra, and INTEGRAL space observatories for several isolated AGNs from 2MIG catalogue, for which the available X-ray data were accessed. Among these objects were CGCG 179-005, NGC 6300, NGC 1050, NGC 2989, WKK 3050, ESO 438-009, and ESO 317-038. We determined corresponding spectral models and values of their parameters (spectral index, intrinsic absorption etc.). X-ray spectra for bright galaxies, NGC 6300 and Circinus, were analyzed up to 250 keV and their characteristics of emission features were determined in 6-7 keV range. We present the results for NGC 1050, NGC 2989, ESO 317-038, and ESO 438-009, for which their spectral parameters were obtained for the first timeWe have analyzed the spectral data obtained by XMM-Newton, Swift, Chandra, and INTEGRAL space observatories for several isolated AGNs from 2MIG catalogue, for which the available X-ray data were accessed. Among these objects were CGCG 179-005, NGC 6300, NGC 1050, NGC 2989, WKK 3050, ESO 438-009, and ESO 317-038. We determined corresponding spectral models and values of their parameters (spectral index, intrinsic absorption etc.). X-ray spectra for bright galaxies, NGC 6300 and Circinus, were analyzed up to 250 keV and their characteristics of emission features were determined in 6-7 keV range. We present the results for NGC 1050, NGC 2989, ESO 317-038, and ESO 438-009, for which their spectral parameters were obtained for the first time