344 research outputs found
Solid-Liquid Phase Diagrams for Binary Metallic Alloys: Adjustable Interatomic Potentials
We develop a new approach to determining LJ-EAM potentials for alloys and use
these to determine the solid-liquid phase diagrams for binary metallic alloys
using Kofke's Gibbs-Duhem integration technique combined with semigrand
canonical Monte Carlo simulations. We demonstrate that it is possible to
produce a wide-range of experimentally observed binary phase diagrams (with no
intermetallic phases) by reference to the atomic sizes and cohesive energies of
the two elemental materials. In some cases, it is useful to employ a single
adjustable parameter to adjust the phase diagram (we provided a good choice for
this free parameter). Next, we perform a systematic investigation of the effect
of relative atomic sizes and cohesive energies of the elements on the binary
phase diagrams. We then show that this approach leads to good agreement with
several experimental binary phase diagrams. The main benefit of this approach
is not the accurately reproduction of experimental phase diagrams, but rather
to provide a method by which material properties can be continuously changed in
simulations studies. This is one of the keys to the use of atomistic
simulations to understand mechanisms and properties in a manner not available
to experiment
Multimode quantum interference of photons in multiport integrated devices
We report the first demonstration of quantum interference in multimode
interference (MMI) devices and a new complete characterization technique that
can be applied to any photonic device that removes the need for phase stable
measurements. MMI devices provide a compact and robust realization of NxM
optical circuits, which will dramatically reduce the complexity and increase
the functionality of future generations of quantum photonic circuits
Arbitrarily loss-tolerant Einstein-Podolsky-Rosen steering allowing a demonstration over 1 km of optical fiber with no detection loophole
Demonstrating nonclassical effects over longer and longer distances is
essential for both quantum technology and fundamental science. The main
challenge is loss of photons during propagation, because considering only those
cases where photons are detected opens a "detection loophole" in security
whenever parties or devices are untrusted. Einstein-Podolsky-Rosen (EPR)
steering is equivalent to an entanglement-verification task in which one party
(device) is untrusted. We derive arbitrarily loss-tolerant tests, enabling us
to perform a detection-loophole-free demonstration of EPR-steering with parties
separated by a coiled 1 km optical fiber, with a total loss of 8.9 dB (87%).Comment: Accepted for publication in Physical Review X. This is the accepted
versio
Weak measurement of photon polarization by back-action induced path interference
The essential feature of weak measurements on quantum systems is the
reduction of measurement back-action to negligible levels. To observe the
non-classical features of weak measurements, it is therefore more important to
avoid additional back-action errors than it is to avoid errors in the actual
measurement outcome. In this paper, it is shown how an optical weak measurement
of diagonal (PM) polarization can be realized by path interference between the
horizontal (H) and vertical (V) polarization components of the input beam. The
measurement strength can then be controlled by rotating the H and V
polarizations towards each other. This well-controlled operation effectively
generates the back-action without additional decoherence, while the visibility
of the interference between the two beams only limits the measurement
resolution. As the experimental results confirm, we can obtain extremely high
weak values, even at rather low visibilities. Our method therefore provides a
realization of weak measurements that is extremely robust against experimental
imperfections.Comment: 11 pages, 3 figure
Testing sequential quantum measurements: how can maximal knowledge be extracted?
The extraction of information from a quantum system unavoidably implies a
modification of the measured system itself. It has been demonstrated recently
that partial measurements can be carried out in order to extract only a portion
of the information encoded in a quantum system, at the cost of inducing a
limited amount of disturbance. Here we analyze experimentally the dynamics of
sequential partial measurements carried out on a quantum system, focusing on
the trade-off between the maximal information extractable and the disturbance.
In particular we consider two different regimes of measurement, demonstrating
that, by exploiting an adaptive strategy, an optimal trade-off between the two
quantities can be found, as observed in a single measurement process. Such
experimental result, achieved for two sequential measurements, can be extended
to N measurement processes.Comment: 5 pages, 3 figure
Creation of maximally entangled photon-number states using optical fiber multiports
We theoretically demonstrate a method for producing the maximally
path-entangled state (1/Sqrt[2]) (|N,0> + exp[iN phi] |0,N>) using
intensity-symmetric multiport beamsplitters, single photon inputs, and either
photon-counting postselection or conditional measurement. The use of
postselection enables successful implementation with non-unit efficiency
detectors. We also demonstrate how to make the same state more conveniently by
replacing one of the single photon inputs by a coherent state.Comment: 4 pages, 1 figure. REVTeX4. Replaced with published versio
Entanglement Dynamics in Two-Qubit Open System Interacting with a Squeezed Thermal Bath via Quantum Nondemolition interaction
We analyze the dynamics of entanglement in a two-qubit system interacting
with an initially squeezed thermal environment via a quantum nondemolition
system-reservoir interaction, with the system and reservoir assumed to be
initially separable. We compare and contrast the decoherence of the two-qubit
system in the case where the qubits are mutually close-by (`collective regime')
or distant (`localized regime') with respect to the spatial variation of the
environment. Sudden death of entanglement (as quantified by concurrence) is
shown to occur in the localized case rather than in the collective case, where
entanglement tends to `ring down'. A consequence of the QND character of the
interaction is that the time-evolved fidelity of a Bell state never falls below
, a fact that is useful for quantum communication applications like
a quantum repeater. Using a novel quantification of mixed state entanglement,
we show that there are noise regimes where even though entanglement vanishes,
the state is still available for applications like NMR quantum computation,
because of the presence of a pseudo-pure component.Comment: 17 pages, 9 figures, REVTeX
Telomeric expression sites are highly conserved in trypanosoma brucei
Subtelomeric regions are often under-represented in genome sequences of eukaryotes. One of the best known examples of the use of telomere proximity for adaptive purposes are the bloodstream expression sites (BESs) of the African trypanosome Trypanosoma brucei. To enhance our understanding of BES structure and function in host adaptation and immune evasion, the BES repertoire from the Lister 427 strain of T. brucei were independently tagged and sequenced. BESs are polymorphic in size and structure but reveal a surprisingly conserved architecture in the context of extensive recombination. Very small BESs do exist and many functioning BESs do not contain the full complement of expression site associated genes (ESAGs). The consequences of duplicated or missing ESAGs, including ESAG9, a newly named ESAG12, and additional variant surface glycoprotein genes (VSGs) were evaluated by functional assays after BESs were tagged with a drug-resistance gene. Phylogenetic analysis of constituent ESAG families suggests that BESs are sequence mosaics and that extensive recombination has shaped the evolution of the BES repertoire. This work opens important perspectives in understanding the molecular mechanisms of antigenic variation, a widely used strategy for immune evasion in pathogens, and telomere biology
Tandem application of C-C bond-forming reactions with reductive ozonolysis
Several variants of reductive ozonolysis, defined here as the in situ generation of aldehydes or ketones during ozonolytic cleavage of alkenes, are demonstrated to work effectively in tandem with a number of C-C bond-forming reactions. For reactions involving basic nucleophiles (1,2- addition of Grignard reagents, Wittig or Horner-Emmons olefinations, and directed Aldol reactions of lithium enolates) the one-pot process offers a rapid and high-yielding alternative to traditional two-step protocols
Silenced yeast chromatin is maintained by Sir2 in preference to permitting histone acetylations for efficient NER
Very little is currently known about how nucleotide excision repair (NER) functions at the ends of chromosomes. To examine this, we introduced the URA3 gene into either transcriptionally active or repressed subtelomeric regions of the yeast genome. This enabled us to examine the repair of ultraviolet (UV)-induced cyclobutane pyrimidine dimers (CPDs) in identical sequences under both circumstances. We found that NER is significantly more efficient in the non-repressed subtelomere than the repressed one. At the non-repressed subtelomere, UV radiation stimulates both histones H3 and H4 acetylation in a similar fashion to that seen at other regions of the yeast genome. These modifications occur regardless of the presence of the Sir2 histone deacetylase. On the other hand, at the repressed subtelomere, where repair is much less efficient, UV radiation is unable to stimulate histone H4 or H3 acetylation in the presence of Sir2. In the absence of Sir2 both of these UV-induced modifications are detected, resulting in a significant increase in NER efficiency in the region. Our experiments reveal that there are instances in the yeast genome where the maintenance of the existing chromatin structures dominates over the action of chromatin modifications associated with efficient NER
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