Assessment of Allelopathic Potential of an Obnoxious Weed-Hyptis Suaveolens (l.) Piot. on the Seed Germination of Crops-Triticum Aestivum L. and Eleusine Coracana Gaertn

The plant, Hyptis suaveolens (L.) Poit. commonly known as Wilayati tulsi belongs to the family Lamiaceae .The plant has been considered as an obnoxious weed, distributed throughout the tropics and subtropics. It is naturalized in India and is considered as a potent invader. Although it has several medicinal properties and used in folklore remedies but its spread is so fast that in due course of its establishment it disrupts the recruitment pattern in the nearby occupied. Not only it restricts the area for other species but it increases livestock pressure on the native species because of its unpalatable nature due to presence of essential oils. However, no information is available in the literature on the allelopathic activity of this obnoxious weed on the germination of the crop plants like Triticum aestivum L., (wheat) and Eleusine coracana Gaertn., (Ragi). The allelopathy of Hyptis suaveolens (L.) Piot., was studied by extracting the crude aqueous extracts- leachates from the leaves of this plant and 3 different concentrations – 0.01%, 0.25% and 1% of these extracts were assessed on the germination of test crops - Triticum aestivum L and Eleusine coracana Gaertn. The linear growth - Root length and Shoot length and the Fresh and Dry matter accumulation were recorded. The Growth equations- Percent Germination of seeds, Percentage Seed mortality, Relative Growth Ratio, Relative Elongation of Shoot, Relative Elongation of Roots, Relative Biomass Ratio and Seed Vigour index of seeds were calculated for the above test crops. The results show that the 1% leachate showed inhibition on all the above mentioned parameters analyzed in Wheat while the same 1% concentration in case of Ragi showed inhibitory effect on Percent Germination of seeds, Percentage Seed mortality, Relative Growth Ratio, Relative Elongation of Shoot and Relative Biomass Ratio While, the Relative Elongation of Roots and Seed Vigour index of seeds were promoted by the sam

Symplastic leiomyoma: a rare clinicopatholgical diagnosis

Although leiomyomas are common this case is being reported due to its uniqueness as it posed challenges at all levels of pathological rarity and management. Symplastic leiomyoma is an unusual benign variant of leiomyoma with less likelihood of malignant transformation. In our case report we present a 28-year-old nulligravida who presented to our OPD with Fibroid uterus detected on scan and myomectomy specimen done revealed a rare pathological diagnosis of symplastic leiomyoma and her followup

Efficacy of terbutaline in preterm labour - our experience

Background: Preterm birth is one of the important causes of perinatal mortality and morbidity in developed countries after congenital malformations. Postponement of delivery plays essential role in preventing such incidences by allowing fetal lung maturity.Methods: This is a prospective study conducted over a period of 20 months among the patients admitted for preterm labour with gestational period between 27 to 36 weeks. After the patients obeyed all the inclusion criteria, they were administered terbutaline 250 µg subcutaneously every 8th hourly followed by 5 mg tablet orally twice daily till contractions ceased. The patients were analysed for gestational period at which they presented with preterm labour contractions, associated risk factors, response to terbutaline, and gestational period at delivery, perinatal complications, neonatal and maternal outcomes. The data obtained were analysed by descriptive analysis.Results: There were 1,678 deliveries during study period, out of which 207 (12%) presented with preterm labour and 20 (~10%) patients received terbutaline. Idiopathic (50%) and vaginal infections (25%) were common causes of preterm labour among the patients who received terbutaline. The labour was prolonged by 3 - 5 days among 8 patients, 7 - 15 days in 9 patients and 15 - 30 days in 3 patients. Common maternal side effects were nausea and tremors. Neonatal outcome was good in most of the cases except in 5 (25%) neonates who required NICU admission but they all recovered well without any morbidity.Conclusions: Administration of terbutaline prolonged labour without any serious maternal complications and better neonatal outcome as 90% of the neonates were born without any complications. Hence, terbutaline can be used as a safe and effective tocolytic agent among patients presenting with preterm labour

A comparative study of intraocular pressure changes in postmenopausal normotensive and hypertensive women

Background: Elevated intraocular pressure is a major modifiable risk factor for preventing glaucoma. Changes in intraocular pressure are directly and significantly associated with changes in blood pressure. Menopausal women with hypertension are at an increased risk of developing elevated intraocular pressure. Aim of current study was to compare the intraocular pressure changes in postmenopausal normotensive and hypertensive women.Methods: 35 normotensive and 35 hypertensive (based on JNC7 classification) postmenopausal women in the age group of 45-55 years participated in the study. Blood pressure was recorded in the sitting position with a mercury sphygmomanometer. Intraocular pressure was measured using Goldmann applanation tonometer.Results: Mean Intraocular Pressure in postmenopausal normotensive women was 13.01 ± 2.61 mmHg while that of postmenopausal hypertensive women was 15.15 ± 2.16 mmHg which was statistically significant. A statistically significant correlation was observed between IOP and systolic blood pressure and positive correlation was obtained between IOP and diastolic blood pressure in postmenopausal hypertensive women.Conclusion: Menopausal women are at an increased risk of developing hypertension due to age, hormonal changes and obesity which may lead to increased IOP. IOP is also directly and significantly related to systemic blood pressure hence postmenopausal women with systemic hypertension need periodic ophthalmologic examination. Detecting early IOP changes will help them in identifying the risk groups and formulating strategies for screening glaucoma.

Noise Reduction In Web Data: A Learning Approach Based On Dynamic User Interests

One of the prominent challenges internet operators encounter is the abundance of extraneous material inside web content, hence impeding the efficient retrieval of relevant information aligned with their evolving interests. The present state of affairs. In academic research, noise is commonly defined as any extraneous data that does not contribute to the intended analysis or study objectives. This study aims to analyse the primary webpage and suggest noise reduction tools for online data. The primary emphasis is on the reduction of noise about the content and its associated factors. The arrangement or organisation of data on the internet. In this paper, including some data inside a dataset may not be universally applicable or appropriate. The web page's primary content pertains to the user's specific interests, while extraneous info is minimised. Noise can be perceived as disruptive or unwanted sound by an individual. Hence, the acquisition of noisy online data and the allocation of resources to user requests ensure not just a decrease in noise levels. There is an observed correlation between the level indicated in a user profile on the web and a reduction in the occurrence of valuable information loss. The inclusion of information consequently enhances the calibre of an online user profile. The phenomenon of noise refers to unwanted or disruptive sounds that can have negative effects on individuals and the Web Data Learning (NWDL) tool/algorithm exhibits the capacity to acquire knowledge. The proposal suggests the use of noise in web user profiles to enhance data privacy. The work that has suggested the removal of noise data in the context of dynamic user behaviour is being considered. The topic of interest is being discussed. To ascertain the efficacy of the proposed study, A presentation of an experimental design arrangement is provided. The results were achieved in contrast to the presently employed algorithms utilised in the context of noisy online data. The reducing process. The experimental findings indicate that the proposed study examines the dynamic evolution of user interest before the removal of extraneous data. The proposed study makes a significant contribution to Enhancing the calibre of an online user profile through the reduction of content volume. The elimination of noise results in the removal of beneficial information

Biomechanical analysis of the effect of ‘intermediate screws’ in short segment posterior fixation of unstable burst fractures of thoracolumbar spine in calf spine model

Background: Efforts in preserving motion levels in unstable thoracolumbar burst fractures steered to short segment fixation. However, short segment spanning fixation in clinical scenario reported high failure rates.  Augmentation of spanning fixation by inserting intermediate screws into the fracture level is proposed to enhance stability. An experimental comparative study was performed to assess the biomechanical role of the ‘intermediate screws.’ Methods: Five calf spine specimens were freshly prepared to record the biomechanical characteristics, range of motion (ROM), and stiffness. CT scan confirmed an unstable burst fracture in each specimen. Each specimen was instrumented with short-segment posterior fixation with an intermediate screw. The same test protocols were repeated with and without intermediate screws. Results: Intermediate screws contribute to 20.2%, 16.5%, 14.5% and 23% decrease in ROM and 15.4%, 25.6%, 48.3%, and 160.2% increase in construct stiffness. Conclusions: Intermediate screws significantly increase the construct stiffness and decrease the ROM. 

Potential of distillery effluents for safe water through vermifiltration

Vermifiltration of wastewater using waste eater earthworms is a newly conceived novel technology. The present study evaluated BOD, COD and TS showing significant variation in decrease by 95%, 90% and 80% respectively through vermifiltration of distillery effluents. The nutrient contents (TN, TP, TK, TCa and TMg) in the vermicasts had increase (1.82 % in TN, 0.24% in TP, 2.15% in TK, 2.07% in TCa and 2.86 % in TMg) in the range of fold than the control level. The morphology of the control and experimental vermicast samples were analyzed with SEM and the image showed significant variation. The FT-IR spectrum analysis showed reduction of aliphatic/aromatic (C=C and OH) compounds in the vermicompost. Thus, the present study significantly highlights the vermifiltration technology in treating distillery effluent

Outpatient prescription audit in a tertiary care hospital at Puducherry

Background: Rational use of medicines promotes good health practices and prevents inappropriate use of medicines, polypharmacy, unnecessary use of antimicrobials, injections, and also encourages use of medicines from essential medicine list and dispensing by generic names. The aim of the study was to analyze the outpatient prescriptions of a tertiary care centre by utilizing World Health Organization (WHO) core drug use prescribing indicators.Methods: A retrospective observational study was conducted in a tertiary care health setup at Puducherry, South India. Outpatient prescriptions from all the major clinical departments were analyzed using WHO prescribing indicators and they were compared with some similar studies.Results: The average number of drugs per prescription was 2.74. The percentage of prescriptions with antibiotics was 20.33% and the percentage of prescriptions with injections was 0.16%. The percentage of drugs prescribed by generic names and from essential medicine list was 83.13% and 87.9 respectively. Further antibiotic utilization was found to be higher in the department of ENT (56.67%), respiratory medicine (45%) and surgery (40%). Percentage of drugs prescribed by generic names in pediatrics and respiratory medicine were found to be 67.88% and 65.27% and percentage of drugs prescribed from essential medicine list in dermatology was 69.62%.Conclusions: Prescription pattern followed in our Institute almost adheres to the guidelines laid down by the WHO. Moreover, it is also implied that a routine audit of this type should be done in health care setups to ensure that they adhere to the WHO guidelines for better health care

AYURVEDA SUCCESSFUL MANAGEMENT OF HEPATITIS B – A CASE STUDY

A successful case study of Ayurveda management of Hepatitis B was reported. A 19 year old patient with classical symptoms of hepatitis B assessed subjectively and objectively and meticulously recorded at all stages. Yellow discoloration of eye, urine, nails and tongue, loss of appetite, generalized itching and fatigue was noted. After enhancing digestive capacity, medicated ghee –‘Vyoshadi grta,’ was administered as per Shaman principles in a dose of 10gm twice daily. Mrudu virechana (mild purgation) induced by Trivrth lehya 20gm which resulted in 5 to 6 Vegas (bouts of loose stools). Agni (digestive capacity) has slowly but gradually increased. Diet quantity and quality was rectified as required. Rasayan prescribed in one single dose daily was Draskhavlehya, after patient showed clinically significant clearance of all symptoms. Rasayana and Ahara vihara management was continued until blood serum hepatitis antigen B reported negative. Liver Function Test, HB percent in laboratory registered normalization and clinical confirmation showed significant results. Photographs of urine and eye documented periodically. Blood reports showed radical improvements. Physically, mentally and spiritually patient has reported wellbeing. Patient moved towards Swasthya (complete wellbeing). This case study guaranteed Ayurveda management as quick, safe and effective. Large scale study was required to reconfirm reports and can be initiated on similar principles and practices