Pequena história de amor conjugal no Ocidente Moderno

This is a brief summary of practices regarding conjugal love, from the end of the Middle Ages to modern times. Continuations and ruptures succeed one another in literature, both profane and sacred, in the vigilance of the Institutions and in the practices of our grandparents in the past, leaving marks on the contemporary world.Se trata de un breve resumen de las prácticas en torno al amor conyugal, desde finales de la Edad Media hasta la Modernidad. Permanencias y rupturas se suceden en la literatura profana y sacra, en la vigilancia de las Instituciones, en la práctica de nuestros ancestros, dejando marcas en las prácticas de la contemporaneidad.Trata-se de um breve resumo das práticas em torno do amor conjugal, desde os finais da Idade Média à Modernidade. Permanências e rupturas se sucedem na literatura profana e sacra, na vigilância das Instituições, na prática de nossos avós do passado, deixando marcas nas práticas da contemporaneidade

Selvagens na igreja a frisa de Saint-Jacques de Dieppe: um caso de bricolagem cultural

Este artigo trata das relações culturais entre a França e o Brasil no século XVI através da imagem de índios e americanos.This article discusses the cultural relationships between France and Brazil during the sixteenth century through the images of Indians and Americans

Ciliary Abnormalities Due to Defects in the Retrograde Transport Protein DYNC2H1 in Short-Rib Polydactyly Syndrome

The short-rib polydactyly (SRP) syndromes are a heterogenous group of perinatal lethal skeletal disorders with polydactyly and multisystem organ abnormalities. Homozygosity by descent mapping in a consanguineous SRP family identified a genomic region that contained DYNC2H1, a cytoplasmic dynein involved in retrograde transport in the cilium. Affected individuals in the family were homozygous for an exon 12 missense mutation that predicted the amino acid substitution R587C. Compound heterozygosity for one missense and one null mutation was identified in two additional nonconsanguineous SRP families. Cultured chondrocytes from affected individuals showed morphologically abnormal, shortened cilia. In addition, the chondrocytes showed abnormal cytoskeletal microtubule architecture, implicating an altered microtubule network as part of the disease process. These findings establish SRP as a cilia disorder and demonstrate that DYNC2H1 is essential for skeletogenesis and growth