18,394 research outputs found
Nonexistence of conformally flat slices of the Kerr spacetime
Initial data for black hole collisions are commonly generated using the
Bowen-York approach based on conformally flat 3-geometries. The standard
(constant Boyer-Lindquist time) spatial slices of the Kerr spacetime are not
conformally flat, so that use of the Bowen-York approach is limited in dealing
with rotating holes. We investigate here whether there exist foliations of the
Kerr spacetime that are conformally flat. We limit our considerations to
foliations that are axisymmetric and that smoothly reduce in the Schwarzschild
limit to slices of constant Schwarzschild time. With these restrictions, we
show that no conformally flat slices can exist.Comment: 5 LaTeX pages; no figures; to be submitted to Phys. Rev.
Continuous-flow laboratory simulation of stream water quality changes downstream of an untreated wastewater discharge.
In regions of the world with poor provision of wastewater treatment, raw sewage
is often discharged directly into surface waters. This paper describes an
experimental evaluation of the fate of two organic chemicals under these
conditions using an artificial channel cascade fed with a mix of settled sewage
and river water at its upstream end and operated under continuous steady-state
conditions. The experiments underpin an environmental risk assessment
methodology based on the idea of an “impact zone” (IZ) – the zone downstream of
wastewater emission in which water quality is severely impaired by high
concentrations of unionised ammonia, nitrite and biochemical oxygen demand
(BOD). Radiolabelled dodecane-6-benzene sulphonate (DOBS) and aniline
hydrochloride were used as the model chemical and reference compound
respectively. Rapid changes in 14C counts were observed with flow-time for both
these materials. These changes were most likely to be due to complete
mineralisation. A dissipation half-life of approximately 7.1 h was observed for
the 14C label with DOBS. The end of the IZ was defined as the point at which the
concentration of both unionised ammonia and nitrite fell below their respective
predicted no-effect concentrations for salmonids. At these points in the
cascade, approximately 83 and 90% of the initial concentration of 14C had been
removed from the water column, respectively. A simple model of mineral nitrogen
transformations based on Michaelis–Menten kinetics was fitted to observed
concentrations of NH4, NO2 and NO3. The cascade is intended to provide a
confirmatory methodology for assessing the ecological risks of chemicals under
direct discharge co
Evidence for a circumplanetary disk around protoplanet PDS 70 b
We present the first observational evidence for a circumplanetary disk around
the protoplanet PDS~70~b, based on a new spectrum in the band acquired with
VLT/SINFONI. We tested three hypotheses to explain the spectrum: Atmospheric
emission from the planet with either (1) a single value of extinction or (2)
variable extinction, and (3) a combined atmospheric and circumplanetary disk
model. Goodness-of-fit indicators favour the third option, suggesting
circumplanetary material contributing excess thermal emission --- most
prominent at m. Inferred accretion rates (-- yr) are compatible with observational
constraints based on the H and Br lines. For the planet, we
derive an effective temperature of 1500--1600 K, surface gravity , radius , mass , and possible thick clouds.
Models with variable extinction lead to slightly worse fits. However, the
amplitude (mag) and timescale of variation
(~years) required for the extinction would also suggest
circumplanetary material.Comment: 8 pages, 2 figures, 1 table. This is a pre-copyedited,
author-produced PDF of an article accepted for publication in ApJL on 2019
May 1
Experimental investigation of shock-cell noise reduction for dual-stream nozzles in simulated flight comprehensive data report. Volume 1: Test nozzles and acoustic data
Parameters which contribute to supersonic jet shock noise were investigated for the purpose of determining means to reduce such noise generation to acceptable levels. Six dual-stream test nozzles with varying flow passage and plug closure designs were evaluated under simulated flight conditions in an anechoic chamber. All nozzles had combined convergent-divergent or convergent flow passages. Acoustic behavior as a function of nozzle flow passage geometry was measured. The acoustic data consist primarily of 1/3 octave band sound pressure levels and overall sound pressure levels. Detailed schematics and geometric characteristics of the six scale model nozzle configurations and acoustic test point definitions are presented. Tabulation of aerodynamic test conditions and a computer listing of the measured acoustic data are displayed
Evaluation of Materials and Concepts for Aircraft Fire Protection
Woven fiberglass fluted-core simulated aircraft interior panels were flame tested and structurally evaluated against the Boeing 747 present baseline interior panels. The NASA-defined panels, though inferior on a strength-to-weight basis, showed better structural integrity after flame testing, due to the woven fiberglass structure
Building brains in a dish: Prospects for growing cerebral organoids from stem cells
AbstractThe recent development of organoid techniques, in which embryonic brain-like tissue can be grown from human or mouse stem cells in vitro offers the potential to transform the way in which brain development is studied. In this review, we summarize key aspects of the embryonic development of mammalian forebrains, focussing in particular on the cerebral cortex and highlight significant differences between mouse and primates, including human. We discuss recent work using cerebral organoids that has revealed key similarities and differences between their development and that of the brain in vivo. Finally, we outline the ways in which cerebral organoids can be used in combination with CRISPR/Cas9 genome editing to unravel genetic mechanisms that control embryonic development of the cerebral cortex, how this can help us understand the causes of neurodevelopmental disorders and some of the key challenges which will have to be resolved before organoids can become a mainstream tool to study brain development
Sediment-moss interactions on a temperate glacier: Falljökull, Iceland
Full text of this article can be found at: http://www.igsoc.org/annals/ Copyright IGS. DOI: 10.3189/172756408784700734We present the results of preliminary investigations of globular moss growth on the surface of Falljökull, a temperate outlet glacier of the Vatnajökull ice cap, southern Iceland. Supraglacial debris has provided a basis for moss colonization, and several large (>500 m2) patches of moss growth (Racomitrium spp.) are observed on the surface of the glacier. Each area of moss-colonized supraglacial debris shows a downslope increase in sphericity and moss cushion size and a decrease in percentage surface coverage of moss-colonized and bare clasts. It is suggested that moss growth on supraglacial debris allows preferential downslope movement of clasts through an associated increase in both overall mass and sphericity. Thermal insulation by moss cushions protects the underlying ice surface from melt, and the resulting ice pedestals assist in downslope sliding and toppling of moss cushions. The morphology and life cycle of supraglacial globular mosses is therefore not only closely linked to the presence and distribution of supraglacial debris, but also appears to assist in limited down-glacier transport of this debris. This research highlights both the dynamic nature of the interaction of mosses with supraglacial sedimentary systems and the need for a detailed consideration of their role within the wider glacial ecosystem.Peer reviewe
Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain
BACKGROUND: Early in mammalian brain development cell proliferation generates a population of progenitor cells whose subsequent divisions produce increasing numbers of postmitotic neurons. Pax6 affects both processes and it has been suggested that this changing role is due at least in part to changes in the relative concentrations of its two main isoforms, (i) Pax6 and (ii) Pax6(5a), created by insertion of a 42 bp exon (exon 5a) into one of the two DNA-binding domains. Crucially, however, no previous study has determined whether the ratio between Pax6 and Pax6(5a) transcripts alters during mammalian neurogenesis in vivo. RESULTS: Using RNase protection assays, we show that Pax6 transcripts are 6–10 times more prevalent than Pax6(5a) transcripts early in neurogenesis in the murine telencephalon, diencephalon and hindbrain and that the ratio later falls significantly to about 3:1 in these regions. CONCLUSION: These changes in vivo are similar in magnitude to those shown previously to alter target gene activity in vitro and might, therefore, allow the single mammalian Pax6 gene to carry out different functions at different times in mammalian brain development
Panax ginseng has no effect on indices of glucose regulation following acute or chronic ingestion in healthy volunteers
In the absence of effective pharmacotherapy for diabetes there has been an increase in the use of, and research into, alternative treatment strategies. These include exercise, dietary interventions and the use of supplements including extracts of ginseng. Two separate, placebo-controlled, double-blind, cross-over studies investigating the effects of chronic ingestion of Panax ginseng (study 1 used G115, study 2 used Cheong Kwan Jang) on glycated Hb (HbA1c; study 1, n 18; study 2, n 11), fasting plasma insulin (study 1, n 17; study 2, n 12), fasting plasma glucose and postprandial response (following breakfast) (study 1, n 23; study 2, n 14) in healthy volunteers are reported. In both studies it was found that Panax ginseng had no effect on any gluco-regulatory parameter investigated. These results are not consistent with those reported for a diabetic sample (albeit using slightly different outcomes). These results would suggest that chronic use of Panax ginseng by non-diabetic individuals will have little long-term effect on glucose regulation. The benefits to glucose regulation associated with long-term ginseng use may only be present in populations with compromised glucose control; however, further research is needed to confirm such a speculation
Understanding initial data for black hole collisions
Numerical relativity, applied to collisions of black holes, starts with
initial data for black holes already in each other's strong field. The initial
hypersurface data typically used for computation is based on mathematical
simplifying prescriptions, such as conformal flatness of the 3-geometry and
longitudinality of the extrinsic curvature. In the case of head on collisions
of equal mass holes, there is evidence that such prescriptions work reasonably
well, but it is not clear why, or whether this success is more generally valid.
Here we study these questions by considering the ``particle limit'' for head on
collisions of nonspinning holes. Einstein's equations are linearized in the
mass of the small hole, and described by a single gauge invariant spacetime
function psi, for each multipole. The resulting equations have been solved by
numerical evolution for collisions starting from various initial separations,
and the evolution is studied on a sequence of hypersurfaces. In particular, we
extract hypersurface data, that is psi and its time derivative, on surfaces of
constant background Schwarzschild time. These evolved data can then be compared
with ``prescribed'' data, evolved data can be replaced by prescribed data on
any hypersurface, and evolved further forward in time, a gauge invariant
measure of deviation from conformal flatness can be evaluated, etc. The main
findings of this study are: (i) For holes of unequal mass the use of prescribed
data on late hypersurfaces is not successful. (ii) The failure is likely due to
the inability of the prescribed data to represent the near field of the smaller
hole. (iii) The discrepancy in the extrinsic curvature is more important than
in the 3-geometry. (iv) The use of the more general conformally flat
longitudinal data does not notably improve this picture.Comment: 20 pages, REVTEX, 26 PS figures include
- …