Chocolate consumption and purchasing behaviour review: Research issues and insights for future research

Chocolate is consumed all over the world. Since its origin, it has undergone many transformations to meet changing market demand. A better understanding of consumer behaviour is a key objective of any business, and so it is for chocolate businesses. In order to fulfil this aim, the current study presents a systematic literature review of consumers' consumption and purchasing behaviour towards cocoa and chocolate. Two databases have been used to collect the literature: Scopus andWeb of Science. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flow diagram was used to identify the articles through the process of data screening and extractions. A total of sixty-four scientific articles have been selected. Research topics, methodological approach and data collection method were identified for each article selected. Then, the identified topics were grouped into four categories in order to obtain a model of major determinants in chocolate consumption: personal preferences, product attributes, socio-demographic factors and economic attributes. Results show that there is a strong focus on Fair Trade in chocolate. Moreover, the current literature review supports the fact that the price and promotion are under-investigated issues. This research represents a valuable tool, especially from a marketing point of view, by creating new channels and new sales opportunities for chocolate products

Does fairness matter? Consumers' perception of fairness in the agro-food chain

IntroductionDefining 'fairness' in the agro-food sector is a challenging task. There is no single definition of fairness and the literature does not provide a complete conceptualization from the consumer's point of view. The current research seeks to explore the consumers' interest in fairness and ethics in the agro-food chain by exploring (i) a comprehensive theoretical framework to conceptualize fairness from a consumer perspective, and (ii) the consumers' perceived importance of different food attributes as fairness-related aspects. MethodLiterature review and focus groups allowed for the creation of the final survey to be submitted to consumers. 529 valid responses from a predominantly Italian female sample were collected. Data were elaborated with Exploratory Factor Analysis and ANOVA test. ResultsThe research identified five dimensions of fairness: Fair price, environment, networking, short chain, and working condition. Also, it emerged that age influences consumers' perceived importance of products with fair attributes. DiscussionThis research contributes to the development of a fairer and more sustainable food system by identifying perceptions of agro-food chain fairness and establishing a link with food shopping intentions. The research provides companies with suggestions on how to expand sales by reaching a greater number of consumers

Prospective study of a molecular selection profile for RAS wild type colorectal cancer patients receiving irinotecan-cetuximab

Background: The aim of our study was to evaluate whether a panel of biomarkers, prospectively analysed might be able to predict patients' clinical outcome more accurately than RAS status alone. Methods: K-RAS (exons 2, 3, 4) wild type colorectal cancer patients, candidates to second/third-line cetuximab with chemotherapy were prospectively allocated into 2 groups on the basis of their profile: favourable (BRAF and PIK3CA exon 20 wild type, EGFR GCN ≥ 2.6, HER-3 Rajkumar score ≤ 8, IGF-1 immunostaining < 2) or unfavourable (any of the previous markers altered or mutated). After the introduction of N-RAS status (exons 2, 3, 4) only RAS wild type patients were considered eligible. Results: Forty-six patients were enrolled. Seventeen patients (37%) were allocated to the favourable and 29 patients (63%) to the unfavourable profile. RR in the favourable and unfavourable group was 11/17 (65%) and 2/29 (7%) (p = 0.007) respectively. The favourable group also showed an improved PFS (8months vs. 3months, p < 0.0001) and OS (15months vs. 6months, p < 0.0001). Conclusions: Our results suggest that prospective selection of optimal candidates for cetuximab treatment is feasible and may be able to improve clinical outcom

Optimization of Machining Fixture for Aeronautical Thin-walled Components☆

Abstract The aim of this work has been the optimization of the fixtures performance used in thin-walled workpiece machining depending on the local rigidity characteristics of the component to be machined. An extensive topology optimization activity has been performed both on fixture-workpiece systems modelled with shell elements and on fixture-workpiece systems modelled with solid elements, varying the topology design variables and/or optimization constraints for each optimization problem, in order to provide a new design of fixture. Finally, a new blended Solid-Lattice design of the fixture, starting by the design topologically optimized, has been created. In this way, it has been possible to identify void regions in the design space, where the material can be removed, regions where solid material is needed, and regions where lattice structure is required. This has allowed to generate the optimal hybrid or blended solid-lattice design based on desired functionality of the part having as natural consequence the definition of a new method for fixtures design

Caspase-independent programmed cell death triggers Ca2PO4 deposition in an in vitro model of nephrocalcinosis

We provide evidence of caspase-independent cell death triggering the calcification process in GDNF-silenced HK-2 cells

Price Fairness of Processed Tomato Agro-Food Chain: The Italian Consumers' Perception Perspective

Food consumers are increasingly searching for emotions and values when purchasing and consuming food. They search for products that ensure social and environmental sustainability, in addition to more common extrinsic product attributes, such as price, packaging, origin, and brand. In particular, there is increasing interest towards product price fairness. The current study aims at exploring consumers’ perception and understanding of price fairness, focusing on the processed tomato products agro-food chain. The study interviewed 832 people. Data were collected through an online questionnaire with the support of Qualtrics software, and data elaboration was carried out with Statistical Package for Social Science (SPSS). The elaboration includes an Exploratory Factor Analysis (EFA) to identify existing latent factors in the consumers’ perception of enabling agro-food system elements influencing farmers’ reception of fair prices. Then, factor mean values were cross-analysed with socio-economic characteristics and processed tomato consumption habits with Analysis of Variance (ANOVA). Results support the idea that consumers are limitedly aware of the processed tomato agro-food chain dynamics and consider farmers as the most unfairly remunerated partner. Women and frequently purchasing consumers of processed tomato products believe farmers should be treated more fairly. There is a difference between what consumers perceive as fair price distribution and actual price distribution among processed tomato chain actors. Further studies may focus on how fairness attribute impacts on consumer purchasing behaviour

Functional needs, emotions, and perceptions of coffee consumers and non-consumers

Coffee is one of the most consumed beverages worldwide. Over the last decades coffee has become a specialty product. Drinking a coffee beverage entails several mixed factors, such as pleasure, experience, lifestyle, and social status. It can also provide an emotional pick-up, both mentally and physically. Only a few studies have explored the motives and emotions of coffee consumption and not consumption. There is limited understanding of consumers' emotional approach towards coffee, and what influences a positive and negative inclination towards coffee consumption. This research fills the current research gaps by addressing three main questions: (i) What are the emotions and habits of coffee consumption? (ii) What are the motives of coffee consumption and non-consumption? and (iii) How relevant is the coffee health impact perception of consuming or not consuming coffee? The research activities include 467 face-to-face interviews with consumers. Interviews are performed in two different countries, Italy and Portugal. Data elaboration includes a principal component analysis carried out to identify latent factors on motives and emotions of consumption in both national groups, and to explore the relationship between the main emotions and consumers' habits and socio-economic characteristics. Results support that consumers have positive emotions from coffee consumption. Perceived emotions are energy, satisfaction, and pleasure. Non-consumption is mainly driven by taste and fear of coffee's health impacts. There are limited differences in the countries analysed. Socio-economic characteristics limitedly influence perceived emotions and consumption motives. To conclude, consumers are increasingly interested in new coffee products. Understanding the functional and emotional factors of coffee consumption contributes to supporting new coffee product development and commercialisation

An inspection system for pharmaceutical glass tubes

Abstract: Syringes, vials and carpules for pharmaceutical products are usually made of borosilicate glass. Such containers are made by glass converting companies starting from single glass tubes. These glass containers can suffer from inclusions, air bubbles, stones, scratches and others issues, that can cause subsequent problems like product contamination with glass particulate or cracks in the glass. In recent years, more than 100 million units of drugs packaged in vials or syringes have been withdrawn from the market. As a consequence pharmaceutical companies are demanding an increased delivery of high quality products to manufacturers of glass containers and therefore of glass tubes. An automatic, vision based, quality inspection system can be devoted to perform such task, but specific process features requires the introduction of ad-hoc solutions: in the production lines tubes significantly vibrate and rotate, and the cylindrical surface of the tube needs to be inspected at 360 degrees. This paper presents the design, the development and the experimental evaluation of a vision system to control the quality of glass tubes, highlighting the specific solutions developed to manage vibrations and rotations, obtaining a 360 degree inspection. The system has been designed and tested in a real facility, and proved effective in identifying defects and impurities in the order of tens of microns

Restoration of anterior teeth using an indirect composite technique. Case report

This article presents a case report of restoration of anterior teeth using an indirect technique with composite veneers in order to restore the dental anatomy and to provide aesthetic and function of anterior teeth. A treatment of upper anterior teeth with indirect microhybrid composite restoration was proposed to a 40-year-old woman with old discolored and fractured ceramic veneers. Upper six anterior teeth were prepared and, after impressions with VPS of maxillary arche, the composite veneers were placed. There are several advantages offered by indirect techniques compared to direct techniques. The increased practice of veneering technique with indirect composites is due to improvement in the properties of composite materials in the last years. The results are very favourable and the patient is satisfied. The restorations with composite veneers have proved durable and aesthetic, protect tooth structure and aesthetic and function is predictably re-established

A Study on Secret Key Rate in Wideband Rice Channel

Standard cryptography is expected to poorly fit IoT applications and services, as IoT devices can hardly cope with the computational complexity often required to run encryption algorithms. In this framework, physical layer security is often claimed as an effective solution to enforce secrecy in IoT systems. It relies on wireless channel characteristics to provide a mechanism for secure communications, with or even without cryptography. Among the different possibilities, an interesting solution aims at exploiting the random-like nature of the wireless channel to let the legitimate users agree on a secret key, simultaneously limiting the eavesdropping threat thanks to the spatial decorrelation properties of the wireless channel. The actual reliability of the channel-based key generation process depends on several parameters, as the actual correlation between the channel samples gathered by the users and the noise always affecting the wireless communications. The sensitivity of the key generation process can be expressed by the secrecy key rate, which represents the maximum number of secret bits that can be achieved from each channel observation. In this work, the secrecy key rate value is computed by means of simulations carried out under different working conditions in order to investigate the impact of major channel parameters on the SKR values. In contrast to previous works, the secrecy key rate is computed under a line-of-sight wireless channel and considering different correlation levels between the legitimate users and the eavesdropper