17 research outputs found

    Implementation of dual stack technique for reducing leakage and dynamic power

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    This paper deals with proposal of a new dual stack approach for reducing both leakage and dynamic powers. The development of digital integrated circuits is challenged by higher power consumption. Thecombination of higher clock speeds, greater functional integration, and smaller process geometries has contributed to significant growth in power density. Scaling improves transistor density and functionality ona chip. Scaling helps to increase speed and frequency of operation and hence higher performance. As voltages scale downward with the geometries threshold voltages must also decrease to gain the performance advantages of the new technology but leakage current increases exponentially. Today leakage power has become anincreasingly important issue in processor hardware and software design. It can be used in various applications like digital VLSI clocking system, buffers, registers, microprocessors etc. The leakage power increases astechnology is scaled down. In this paper, we propose a new dual stack approach for reducing both leakage and dynamic powers. Moreover, the novel dual stack approach shows the least speed power product whencompared to the existing methods. All well known approach is “Sleep” in this method we reduce leakage power. The proposed Dual Stack approach we reduce more power leakage. Dual Stack approach uses theadvantage of using the two extra pull-up and two extra pull-down transistors in sleep mode either in OFF state or in ON state. Since the Dual Stack portion can be made common to all logic circuitry, less number of transistors is needed to apply a certain logic circuit.The dual stack approach shows the least speed power product among all methods. The Dual Stack technique provides new ways to designers who require ultra-low leakage power consumption with much less speedpower product

    Proteomics in India: the clinical aspect

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    Pharmacological profiling of Argemone mexicana for its aphrodisiac potentials in male Wistar rats

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    Objective: To study the aphrodisiac potentials of ethanol extract of Argemone mexicana L. (A. mexicana) of Papaveraceae family in sexually sluggish male Wistar rats. Methods: The sexually inactive male rats were divided into two groups of 8 rats each. The test group animals were treated with ethanol extract of A. mexicana (EEAM) at 1 g/kg daily oral dose for 28 days. Other group animals were treated with sildenafil citrate at an oral dose of 5 mg/kg. The latencies of mount, intromission, ejaculation; post ejaculatory pause and frequencies of mount, intromission, and ejaculation were measured on 0, 7th, 14th, 21st and 28th days. Serum testosterone levels were estimated using ELISA. Results: The EEAM was nonlethal even at dose of 4.0 g/kg. The oral dosing of EEAM has significantly enhanced the orientation of males towards female by increase in ano-genital investigatory behavior, frequencies of mount, intromission, and ejaculation (P< 0.01). The latencies of mount, intromission and ejaculation were significantly decreased (P<0.05). The EEAM has produced marked variation in sexual behavior characteristics and was able to elevate the serum testosterone levels (P<0.01) on par to that of sildenafil citrate. Conclusion: The EEAM has elevated sexual dysfunctions in male rats. These potentials may be related to protopine alkaloids and flavanols by means of physiological stimulus for penile vasculature. Thus, results support the use of EEAM in enhancing sexual behavior in sluggish male rats

    <span style="font-size:11.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-bidi-font-family: Mangal;mso-ansi-language:EN-GB;mso-fareast-language:EN-US;mso-bidi-language: HI" lang="EN-GB">Effect of <i style="mso-bidi-font-style:normal">Argemone mexicana</i> (L.) against lithium-pilocarpine induced <i style="mso-bidi-font-style:normal">status epilepticus</i> and oxidative stress in wistar rats</span>

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    31-35Argemone mexicana (L.) has a role in the treatment of epileptic disorders in Indian traditional system of medicine. We studied its effect on induced <i style="mso-bidi-font-style: normal">status epilepticus (SE) and oxidative stress in rats. SE was induced in male albino rats by administration of pilocarpine (30 mg/kg, ip) 24 h after injection of lithium chloride (3 mEq/kg, ip). Different doses of the ethanol extract of A. mexicana<span style="mso-bidi-font-weight: bold"> were administered orally 1 h before the injection of pilocarpine. The severity of SE was observed and recorded every 15 min for 90 min and thereafter at every 30 min for another 90 min, using the Racine scoring system. In vivo lipid peroxidation of rat brain tissue was measured utilizing thiobarbiturate-reactive substances. Both in vitro free radical nitric oxide and 2,2-diphenyl-1-picryl hydrazyl scavenging activities of the extract were also determined. The SE severity was significantly reduced following oral administration of the extract at 250, 500 and 1000 mg/kg doses. None of the animals from groups 3 to 5 (with A. mexicana extract) have exhibited forelimb clonus of stage 4 seizure. The extract also exhibited both in vivo and <i style="mso-bidi-font-style: normal">in vitro antioxidant activities. </span

    Identification of groundwater contamination zones and its sources by using multivariate statistical approach in Thirumanimuthar sub-basin, Tamil Nadu, India

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    Hydrogeochemical studies have been made in the study area by using multivariate statistical analysis, which is mainly helpful for interpretation of complex data matrices to better understand the geochemical evolution of the area and it allows identifying the possible factors/sources that influence water systems. The spatial distribution of electrical conductivity reveals that an untreated industrial effluents, landfill and anthropogenic activities affecting their groundwater quality in its vicinity and the surrounding area. The dominance of ions was in the order of Na+ > Ca2+ > Mg2+ > K+ = Cl− > HCO3 − > SO4 2− > NO3 − and Ca2+ > Mg2+ > Na+ > K+ = HCO3 − > Cl− > NO3 − > SO4 2− during pre monsoon (PRM) and post monsoon (POM), respectively. The statistical results reveals that the groundwater chemistry gets altered by silicate weathering, ion exchange, leaching, anthropogenic input from agricultural return flow and longer distance of migrating groundwater. The hydrogeochemical regimes are distributed along the upstream side, northwestern, western and eastern parts of the study area. The study highlights the descriptive capabilities of conventional and multivariate techniques as effective tools in groundwater evaluation
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