Self-concept and facial appearance of individuals with an intellectual disability:A scoping review

This paper looks at how self-concept is related to facial appearance. Very little information can be found on how persons with intellectual disabilities think and feel about their own facial appearance. In this review 19 articles on subject of self-concept in people with intellectual disabilities were included. Results show that self-concept of individuals with intellectual disabilities is affected by the relationships they have (positively and negatively). The perceptions of caregivers, peers and their awareness of stigma effects self-concept. How facial appearance affects the self-concept of persons with intellectual disabilities remains unclear and should be a focus of research in future. Abstract: Background The mental health and well-being of individuals can be positively affected by improving facial appearance through orthodontic treatment. However, research is limited on the relationship between facial appearance and self-concept of individuals with intellectual disabilities. Materials and methods This scoping review includes 19 articles and is aimed to examine the self-concept of individuals with intellectual disabilities and determine how the self-concept might be impacted by facial appearance. Furthermore, this review is exploratory in the way that an attempt was made to extract constructs that contribute to the self-concept of persons with intellectual disabilities. Results Unfortunately, no articles were found on how individuals with intellectual disabilities think about their own facial appearance. However, the articles on self-concept in persons with intellectual disabilities do mention some interesting facts: social comparisons lead to social stigma that can contribute negatively to the self-concept of individuals with intellectual disabilities. Also, the ability to communicate and express oneself can contribute to one's self-esteem. Furthermore, parents/caregivers often influence the concept of oneself. Moreover, an individual's relationship with their social environment defines their self-concept. Conclusion It is currently unknown how individuals with intellectual disabilities view their own facial appearance and whether their self-concept is influenced by their appearance. Questionnaires which address attitudes on facial appearance could provide a deeper understanding of the self-concept of individuals with intellectual disabilities and possibly make way for orthodontic treatment. However, caution is needed concerning changing the physical appearance of persons with intellectual disabilities. One should also battle stigma by encouraging the social inclusion of persons with intellectual disability

The p53 target protein Wig-1 binds hnRNP A2/B1 and RNA Helicase A via RNA

AbstractThe p53-induced Wig-1 gene encodes a double stranded RNA-binding zinc finger protein. We generated Saos-2 osteosarcoma cells expressing tetracycline-inducible Flag-tagged human Wig-1. Induction of Wig-1 expression by doxycycline inhibited cell growth in a long-term assay but did not cause any changes in cell cycle distribution nor increased fraction of apoptotic cells. Using co-immunoprecipitation and mass spectrometry, we identified two Wig-1-binding proteins, hnRNP A2/B1 and RNA Helicase A, both of which are involved in RNA processing. The binding was dependent on the presence of RNA. Our results establish a link between the p53 tumor suppressor and RNA processing via hnRNPA2/B1 and RNA Helicase A.Structured summaryMINT-6542926, MINT-6542899:WIG1 (uniprotkb:Q9HA38) physically interacts (MI:0218) with hnRNP A2/B1 (uniprotkb:P22626) by anti bait coimmunoprecipitation (MI:0006)MINT-6542945:RHA (uniprotkb:Q08211) physically interacts (MI:0218) with hnRNP A2/B1 (uniprotkb:P22626) by anti bait coimmunoprecipitation (MI:0006)MINT-6542918, MINT-6542891:WIG1 (uniprotkb:Q9HA38) physically interacts (MI:0218) with RHA (uniprotkb:Q08211) by anti bait coimmunoprecipitation (MI:0006)MINT-6542867:WIG1 (uniprotkb:Q9HA38) physically interacts (MI:0218) with RHA (uniprotkb:Q08211) by anti tag coimmunoprecipitation (MI:0007)MINT-6542879:WIG1 (uniprotkb:Q9HA38) physically interacts (MI:0218) with hnRNP A2/B1(uniprotkb:P22626) by anti tag coimmunoprecipitation (MI:0007

Den frånvarande dialogen : Om en utbildningssatsning inom demensvård

Educational investments may serve several purposes. They can be carried out in order to increase the students’ knowledge within a specific discipline, but also to increase the level of knowledge within an organization. ’Silviahemmet’ in Stockholm, which was inaugurated in the year of 1996, had as one of its objectives to become a school for education of assistant nurses working in the area of dementia care. The educational program had the aim to educate assistant nurses to become supervisors in dementia care, the assistant nurses should acquire an edge competence in the close care of patients with dementia. This educational investment has been investigated in order to study the significance an educational investment may have for a health care organization in which some of the health care personnel has participated in an education and moreover, to study how this knowledge is communicated within the organization. Thus, the overall purpose of my study is to describe and analyse the significance an educational investment is given, by the participating assistant nurses as well as by other health care personnel. The study was carried out during the year 2005 and concerned assistant nurses educated in the years between 1996 and 2001. Four different data gathering techniques were used; questionnaires, interviews, observations at two workplaces and conversations with health care personnel. The questionnaire concerned all 34 assistant nurses who had participated in specialist training in dementia care during this period. Seven persons were interviewed. Summing up my results, the knowledge that the assistant nurses have achieved from the education is theoretical and social knowledge of dementia. This constituted a platform to stand on for the assistant nurses in their work when meeting the patient An important result of the study, concerning the importance of the assistant nurses specialist training for other categories of health care personnel, is the lack of verbal communication between personnel categories that seems to be at hand. Furthermore, dialogues or shared reflections among the personnel could not be noticed. Often it was solely one-way communication that existed on the wards. A knowledge creating dialogue was missing. Questions were asked, but only regarding about "what" and "when" a work task should be performed, not "why" something should be carried out. An obstacle regarding the communication of new knowledge appears to be the gap existing between an educational investment and the everyday reality of the health care organization. The result of the study shows the importance of adopting the theoretical knowledge to the reality that the health care personnel is facing. Other obstacles seem to be status and hierarchies. The study showed that the assistant nurses working hours did not allow for educating health care personnel in dementia. There ought to be possibilities within the organization to make space for the use and communication of new knowledge through the supervising of health care personnel caring for elderly with dementia. This in turn may lead to better health care for elderly. This supervision could take the form of a dialogue and shared reflections concerning the patients and their need of health care. Keywords: Educational investment, learning, health professionals, elderly care, communication . The theory and the meeting with the patient in practice formed an overall understanding and knowledge regarding all dimensions of dementia. The education also resulted in a strengthened self-confidence of the participants. The feeling of confidence in the newly acquired knowledge seems to have contributed to a professional development. Further, it proved to take time for the assistant nurses to enter their new role as specialists within dementia care. It was revealed that they did not get enough time from their employer to educate the health care personnel. Moreover, it was not easy to return to the old workplace, especially regarding the relation to old working colleagues and nurses. The assistant nurses described this as a feeling that they had to balance their comportment on the wards in order not to take up too much space

Presurgical orthopedics and satisfaction in motherhood: a randomized clinical trial (Dutchcleft).

Contains fulltext : 71391.pdf (publisher's version ) (Closed access)OBJECTIVE: To study the effect of infant orthopedics on satisfaction in motherhood. DESIGN: Prospective two-arm randomized controlled trial in parallel with three participating academic cleft palate centers. Treatment allocation was concealed and was performed by means of a computerized balanced allocation method. Setting: Cleft palate centers of Amsterdam, Nijmegen, and Rotterdam, the Netherlands. PATIENTS: Two groups of infants with complete unilateral cleft lip and palate and no other malformations. INTERVENTIONS: Group IO+ (n = 27) wore passive maxillary plates during the first year of life, group IO- (n = 27) did not. MAIN OUTCOME MEASURE(S): Mean satisfaction scores were obtained from completed questionnaires at 6, 24, and 58 weeks of age. A 4-point scale was used (1 = very satisfactory to 4 = very unsatisfactory). RESULTS: The range of the mean scores for the individual items on the questionnaires for both groups ranged between 1.1 and 2.4. No differences were found between groups. Mothers appear to be satisfied in motherhood, least satisfied with the available time for themselves, and very satisfied with hugging and walking their babies. No differences were found between groups. CONCLUSIONS: Results from the present study show that infant orthopedics, with a passive plate during the first year of life, in children with a unilateral cleft lip and palate has no influence on the mothers' satisfaction in motherhood

Death and caring for dying patients : exploring first-year nursing students' descriptive experiences

Aim: To describe first-year nursing student`s expereinces of witnessing death and providing end-of-life care. Methods: This study is a part of a larger longitudial prject. Interviews (n=17) were conducted with nursing students at the end of their fisrt year of education. To analyse the interviews (lived-expereince description), a thematic analysis, "a search for meaning" (Van Manen, 1997) was applied. Result: The results are presented within the framework of four separate themes: (1) The thought of death is more frightening than the actual epereince, (2) Daring to approach the dying patient and offering something of oneself, (3) The expereince of not sufficing in the face of death and (4) being confronted with one`s own feelings. Conclusion: Nursing students require continous support and opportunity to reflect and discuss their experiences about caring for dying patients and confronting death throughout the entirety of their education. In addition, teachers and clinical superviosors need t give support using reflective practice to help students to devlo confidence in their capacity for caring dying patients.Sjuksköterskestudenters erfarenheter av och attityder till att vårda döende personer som grund för utveckling av undervisning i pallaitiv vår

The development of the cleft aesthetic rating scale: A new rating scale for the assessment of nasolabial appearance in complete unilateral cleft lip and palate patients

Objective: The development of the Cleft Aesthetic Rating Scale, a simple and reliable photographic reference scale for the assessment of nasolabial appearance in complete unilateral cleft lip and palate patients. Design: A blind retrospective analysis of photographs of cleft lip and palate patients was performed with this new rating scale. Setting: VU Medical Center Amsterdam and the Academic Center for Dentistry of Amsterdam. Patients: Complete unilateral cleft lip and palate patients at the age of 6 years. Main Outcome Measures: Photographs that showed the highest interobserver agreement in earlier assessments were selected for the photographic reference scale. Rules were attached to the rating scale to provide a guideline for the assessment and improve interobserver reliability. Cropped photographs revealing only the nasolabial area were assessed by six observers using this new Cleft Aesthetic Rating Scale in two different sessions. Results: Photographs of 62 children (6 years of age, 44 boys and 18 girls) were assessed. The interobserver reliability for the nose and lip together was 0.62, obtained with the intraclass correlation coefficient. To measure the internal consistency, a Cronbach alpha of .91 was calculated. The estimated reliability for three observers was .84, obtained with the Spearman Brown formula. Conclusion: A new, easy to use, and reliable scoring system with a photographic reference scale is presented in this study

Infant orthopedics in UCLP: effect on feeding, weight, and length: a randomized clinical trial (Dutchcleft).

Contains fulltext : 48048.pdf (publisher's version ) (Closed access)OBJECTIVE: To study the effects of infant orthopedics (IO) on feeding, weight, and length. DESIGN: Prospective two-arm randomized controlled trial in three academic Cleft Palate Centers. Treatment allocation was concealed and performed by means of a computerized balanced allocation method. SETTING: Cleft Palate Centers of Amsterdam, Nijmegen, and Rotterdam, the Netherlands. PATIENTS: Infants with complete unilateral cleft lip and palate (UCLP), no other malformations. INTERVENTIONS: One group (IO+) wore passive maxillary plates during the first year of life, but the other group (IO-) did not. All other interventions were the same for both groups. MAIN OUTCOME MEASURES: Bottle feeding velocity (mL/min) at intake, 3, 6, 15, and 24 weeks (T0 to T24); weight-for-age, length-for-age, and weight-for-length using z scores; reference values from the Netherlands' third nationwide survey on growth. RESULTS: Feeding velocity increased with time from 2.9 to 13.2 mL/min in the IO- group and from 2.6 to 13.8 mL/min in the IO+ group; no significant differences were found between groups. Weight-for-age, length-for-age, and weight-for-length (z scores) did not differ significantly between groups, but overall the infants with unilateral cleft lip and palate in both groups had significantly lower mean z scores for weight-for-age and height-for-age than the reference during the first 14 months, and had lower mean values for weight-for-length after soft palate closure. CONCLUSION: Infant orthopedics with the aim of improving feeding and consequent nutritional status in infants with unilateral cleft lip and palate can be abandoned