Thermodynamic Properties of N-Methyl-Substituted Ethane-1,2-diamines: Experimental and Computational Study

© 2016 American Chemical Society.Vapor pressures for four N-methyl-substituted ethane-1,2-diamines were measured using the transpiration method. Enthalpies of vaporization were derived from the temperature dependence of the vapor pressures. Consistency of the experimental data was assessed and confirmed with group-additivity (GA) and quantum-chemical (QC) methods. Further confirmation of the results is provided through combined assessment with properties reported in the literature for the parent compound ethane-1,2-diamine and a group of alkyl-substituted alkane-1,2-diamines. The effective application of modern QC methods in critical evaluation of enthalpies of vaporization and enthalpies of formation is demonstrated

Experimental comparison of induction and synchronous reluctance electric drive performance

Работа имеет целью экспериментальное сравнение конструктивных и энергетических характеристик современных асинхронных двигателей (АД) отечественного и зарубежного производства (ABB) и разработанного авторами синхронного реактивного двигателя (СРД) в составе частотно-регулируемого электропривода. Рассматриваемый в работе опытный образец двигателя спроектирован на основе статора АД. Результаты работы показывают, что применение СРД позволяет значительно повысить КПД частотно-регулируемого привода. При этом СРД может соответствовать самому высокому классу энергоэффективности IE4. В то же время конструкция двигателя остается простой и дешевой.The work is aimed at experimental comparison of constructive and energy characteristics of modern asynchronous electric motors of Russian and European manufacturers (ABB Ltd.) and the synchronous reluctance motor developed by the authors as a part of variable frequency drive. The prototype motor was designed based on the stator of an induction motor. The issues show that it is possible to significantly improve the efficiency of the variable frequency drive by use of a synchronous reluctance motor. The motor can correspond to the highest energy efficiency class IE4. At the same time the motor design is simple and cheap

Synthesis and antimicrobial activity of carboxylate phosphabetaines derivatives with alkyl chains of various lengths

The purpose of the present study was to investigate the antibacterial activity of fifteen novel nanosized alkyl esters of carboxylate phosphabetaine: β-(carboxyalkyl)ethyltriphenylphosphonium bromides 4-8, β-(carboxyalkyl)-β-methylethyltriphenylphosphonium bromides 9-13, and β-(carboxyalkyl)-α-methylethyltriphenylphosphonium bromides 14-18. The in vitro microbiological activity of the synthesized phosphonium bromides against gram-positive and gram-negative bacteria and the yeast Candida albicans was determined in comparison to standard agents. Microbiological results indicate that the synthesized phosphonium salts 4-18 possess a broad spectrum of activity against the tested microorganisms. Every newly synthesized compound was characterized by elemental analyses, IR, 1H NMR, and 31P NMR spectral studies. © 2013 Irina V. Galkina et al

Synthesis and antimicrobial activity of bis-4,6-sulfonamidated 5,7-dinitrobenzofuroxans

A new series of bis-4,6-sulfonamidated 5,7-dinitrbenzofuroxans 7-11 had been synthesized and tested for antimicrobial activity. The structures of new sulfanilamide derivatives were characterized by elemental analysis, IR spectroscopy, and mass spectrometry (MALDITOF). The synthesized compounds were tested for their in vitro antimicrobial activity using the disk diffusion method against Gram-positive bacteria Staphylococcus aureus; the Gram-negative bacteria Escherichia coli, Pseudomonas aeruginosa, and Proteus mirabilis; the fungal strain Aspergillus niger; and the yeast-like pathogenic fungus Candida albicans. Our results indicate that the compounds 7-11 exhibit potent antimicrobial activity. The stability of the compounds was evaluated by TG and DSC methods. © 2014 Irina V. Galkina et al

Synthesis and biological evaluation of novel carboxylate phosphabetaines derivatives with long alkyl chains

© 2016 Taylor & Francis Group, LLC.The purpose of the present study was to investigate the antibacterial activity of novel alkyl esters of carboxylate phosphabetaine: β-(carboxyalkyl)ethyltributylphosphonium bromides 4–8. The in vitro microbiological activity of the synthesized phosphonium bromides against gram-positive, gram-negative bacteria and the yeast Candida albicans was determined in comparison to standard agents. Microbiological results indicate the synthesized phosphonium salts possess a broad spectrum of activity against the testedmicroorganisms. Every newly synthesized compound was characterized by elemental analyses, IR, 1H NMR, 31P NMR spectral studies

Synthesis and structure of novel phosphorylated azomethines

© 2016 Taylor & Francis Group, LLC.The condensation of do-, hexa-, octadecan-1-amines with bromo- and nitrobenzaldehydes yielded a series of Schiff bases in good yields. Subsequent reaction of these compounds with dioctylphosphine oxide yielded phosphorylated azomethines and some were characterized using X-ray crystallography. The structure of the isolated compounds was determined by IR and NMR spectroscopy, elemental analysis, and their thermal stability was studied by simultaneous thermogravimetry and differential scanning calorimetry. All of the synthesized compounds were tested for their antibacterial and anti-Candida activity. A number of the compounds exhibited antimicrobial activity comparable to that of the commercially available drugs, ciprofloxacin and clotrimazole

Tumor Necrosis Factor-mediated survival of CD169⁺ cells promotes immune activation during vesicular stomatitis virus infection

Innate immune activation is essential to mount an effective antiviral response and to prime adaptive immunity. Although a crucial role of CD169+ cells during vesicular stomatitis virus (VSV) infections is increasingly recognized, factors regulating CD169+ cells during viral infections remain unclear. Here, we show that tumor necrosis factor is produced by CD11b+ Ly6C+ Ly6G+ cells following infection with VSV. The absence of TNF or TNF receptor 1 (TNFR1) resulted in reduced numbers of CD169+ cells and in reduced type I interferon (IFN-I) production during VSV infection, with a severe disease outcome. Specifically, TNF triggered RelA translocation into the nuclei of CD169+ cells; this translocation was inhibited when the paracaspase MALT-1 was absent. Consequently, MALT1 deficiency resulted in reduced VSV replication, defective innate immune activation, and development of severe disease. These findings indicate that TNF mediates the maintenance of CD169+ cells and innate and adaptive immune activation during VSV infection

The main directions of the development of snowmobiles in the Russian Federation

This article describes such constructive units of domestic snowmobiles as gasoline engines, layout schemes and types of platforms, caterpillar propulsions unit and caterpillars, front and rear suspension, steering, transmission and brake systems

The main directions of the development of snowmobiles in the Russian Federation

This article describes such constructive units of domestic snowmobiles as gasoline engines, layout schemes and types of platforms, caterpillar propulsions unit and caterpillars, front and rear suspension, steering, transmission and brake systems