Socially situated perfectionism in a high school choir

School choirs, bands, and orchestras in the United States have long been guided by exacting standards of performance practice that require high levels of technical proficiency. Such ensembles are also socially situated, requiring interpersonal interaction as participants work toward achieving a shared set of goals. These factors could combine to exacerbate individuals’ perceived pressure to meet goals. Hewitt and Flett (1991) called this pressure socially situated perfectionism. Some researchers have argued that perfectionism might be tempered or exacerbated in certain environments (Damien et al., 2014; Dunn et al., 2012; Flett & Hewitt, 2002; Hewitt et al., 2003; McArdle, 2010; Mouratidis & Michou, 2011). The purpose of this study was to investigate the experiences of perfectionistic students, particularly their perceptions of expectations, self-worth, and acceptance associated with socially situated perfectionism, in a high school choral classroom. In order to carry out this examination, a multiple case study methodology was employed; three high school students and their choir director were interviewed and observed in choral rehearsals, with students also asked to journal about their experiences. To varying degrees across cases and within cases, participants displayed behaviors that aligned with descriptions of socially situated perfectionism outlined by Hewitt and Flett (1991). The presence of these behaviors suggests that perfectionism may play a role in their music making. It appears likely that the choral classroom environment, as facilitated by the instructor and including instructor critique/feedback as well as peer interactions, merits further study for its potential role in abating or exacerbating perfectionistic tendencies in certain individuals

The Cerebral Microvasculature in Schizophrenia: A Laser Capture Microdissection Study

BACKGROUND: Previous studies of brain and peripheral tissues in schizophrenia patients have indicated impaired energy supply to the brain. A number of studies have also demonstrated dysfunction of the microvasculature in schizophrenia patients. Together these findings are consistent with a hypothesis of blood-brain barrier dysfunction in schizophrenia. In this study, we have investigated the cerebral vascular endothelium of schizophrenia patients at the level of transcriptomics. METHODOLOGY/PRINCIPAL FINDINGS: We used laser capture microdissection to isolate both microvascular endothelial cells and neurons from post mortem brain tissue from schizophrenia patients and healthy controls. RNA was isolated from these cell populations, amplified, and analysed using two independent microarray platforms, Affymetrix HG133plus2.0 GeneChips and CodeLink Whole Human Genome arrays. In the first instance, we used the dataset to compare the neuronal and endothelial data, in order to demonstrate that the predicted differences between cell types could be detected using this methodology. We then compared neuronal and endothelial data separately between schizophrenic subjects and controls. Analysis of the endothelial samples showed differences in gene expression between schizophrenics and controls which were reproducible in a second microarray platform. Functional profiling revealed that these changes were primarily found in genes relating to inflammatory processes. CONCLUSIONS/SIGNIFICANCE: This study provides preliminary evidence of molecular alterations of the cerebral microvasculature in schizophrenia patients, suggestive of a hypo-inflammatory state in this tissue type. Further investigation of the blood-brain barrier in schizophrenia is warranted

TRY plant trait database – enhanced coverage and open access

Plant traits - the morphological, anatomical, physiological, biochemical and phenological characteristics of plants - determine how plants respond to environmental factors, affect other trophic levels, and influence ecosystem properties and their benefits and detriments to people. Plant trait data thus represent the basis for a vast area of research spanning from evolutionary biology, community and functional ecology, to biodiversity conservation, ecosystem and landscape management, restoration, biogeography and earth system modelling. Since its foundation in 2007, the TRY database of plant traits has grown continuously. It now provides unprecedented data coverage under an open access data policy and is the main plant trait database used by the research community worldwide. Increasingly, the TRY database also supports new frontiers of trait‐based plant research, including the identification of data gaps and the subsequent mobilization or measurement of new data. To support this development, in this article we evaluate the extent of the trait data compiled in TRY and analyse emerging patterns of data coverage and representativeness. Best species coverage is achieved for categorical traits - almost complete coverage for ‘plant growth form’. However, most traits relevant for ecology and vegetation modelling are characterized by continuous intraspecific variation and trait–environmental relationships. These traits have to be measured on individual plants in their respective environment. Despite unprecedented data coverage, we observe a humbling lack of completeness and representativeness of these continuous traits in many aspects. We, therefore, conclude that reducing data gaps and biases in the TRY database remains a key challenge and requires a coordinated approach to data mobilization and trait measurements. This can only be achieved in collaboration with other initiatives

Rh-Mediated C1-Polymerization: Copolymers from Diazoesters and Sulfoxonium Ylides

In this paper, we present new results obtained in our investigations of Rh-catalyzed C1 (co)polymerization reactions using carbene units as monomers. We demonstrate here, for the first time, the use of transition metal catalysts in carbene polymerization using sulfur ylides as the carbene monomer precursors. Furthermore, we show that it is possible to generate unique diblock copolymers from sulfoxonium ylides and diazoesters as the respective carbene monomer precursors. This constitutes an entirely new approach to the synthesis of functional copolymers. The copolymerization reactions were successful, and high-Mw poly(methylene)-poly(ester carbene) copolymers were obtained with a diblock-syndiotactic microstructure in decent yields. These copolymers can be used as blending agents to mix polyethylene or polymethylene with poly(ethyl 2-ylidene-acetate). The copolymer properties are highly dependent on the functional-group content. Model studies and investigations on the influence of the catalyst structure on the obtained polymer yields provide insights into the catalyst activation and deactivation processes operative under the applied reaction conditions

Variation in reproductive success across captive populations:methodological differences, potential biases and opportunities

Our understanding of fundamental organismal biology has been disproportionately influenced by studies of a relatively small number of ‘model’ species extensively studied in captivity. Laboratory populations of model species are commonly subject to a number of forms of past and current selection that may affect experimental outcomes. Here, we examine these processes and their outcomes in one of the most widely used vertebrate species in the laboratory – the zebra finch (Taeniopygia guttata). This important model species is used for research across a broad range of fields, partly due to the ease with which it can be bred in captivity. However despite this perceived amenability, we demonstrate extensive variation in the success with which different laboratories and studies bred their subjects, and overall only 64% of all females that were given the opportunity, bred successfully in the laboratory. We identify and review several environmental, husbandry, life-history and behavioural factors that potentially contribute to this variation. The variation in reproductive success across individuals could lead to biases in experimental outcomes and drive some of the heterogeneity in research outcomes across studies. The zebra finch remains an excellent captive animal system and our aim is to sharpen the insight that future studies of this species can provide, both to our understanding of this species and also with respect to the reproduction of captive animals more widely. We hope to improve systematic reporting methods and that further investigation of the issues we raise will lead both to advances in our fundamental understanding of avian reproduction as well as to improvements in future welfare and experimental efficiency