11,579 research outputs found
Prognostic significance of short-term blood pressure variability in acute stroke
Background and Purpose—
Blood pressure variability (BPV) may be an important prognostic factor acutely after stroke. This review investigated the existing evidence for the effect of BPV on outcome after stroke, also considering BPV measurement techniques and definitions.
Methods—
A literature search was performed according to a prespecified study protocol. Two reviewers independently assessed study eligibility and quality. Where appropriate, meta-analyses were performed to assess the effect of BPV on poor functional outcome.
Results—
Eighteen studies from 1359 identified citations were included. Seven studies were included in a meta-analysis for the effect of BPV on functional outcome (death or disability). Systolic BPV was significantly associated with poor functional outcome: pooled odds ratio per 10-mm Hg increment, 1.2; confidence interval (1.1–1.3). A descriptive review of included studies also supports these findings, and in addition, it suggests that systolic BPV may be associated with increased risk of intracranial hemorrhage in those treated with thrombolytic therapy.
Conclusions—
This systematic review and meta-analysis suggest that greater systolic BPV, measured early from ischemic stroke or intracerebral hemorrhage onset, is associated with poor longer-term functional outcome. Future prospective studies should investigate how best to measure and define BPV in acute stroke, as well as to determine its prognostic significance.
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Is Brazil really a catholic country? What opinions about abortion, sex between individuals who are not married to each other, and homosexuality say about the meaning of catholicism in three Brazilian cities
The idea of being a Catholic country is quite widespread throughout the nation. What does it mean to be Catholic in Brazil? Do Catholics follow the Catholic Doctrine? The objective of this paper is to investigate the relationship between religion and religious involvement (measured by religious affiliation and service attendance) and opinions about abortion, sex between individuals who are not married to each other, and homosexuality in São Paulo, Porto Alegre, and Recife. Data come from the survey “Spirit and Power: A 10-Country Survey of Pentecostals,” carried out in 2006. Results suggest that Brazilian Catholics are a very heterogeneous group with respect to opinions about abortion and sex between individuals who are not married to each other. In addition, service attendance among Catholics and those opinions are strongly correlated, except for the case of homosexuality, a topic which Catholics tend to have the same opinions about, irrespective of their religious involvement. Committed Protestants are, by far and away, the most conservative group.Brazil
The Peak Brightness and Spatial Distribution of AGB Stars Near the Nucleus of M32
The bright stellar content near the center of the Local Group elliptical
galaxy M32 is investigated with 0.12 arcsec FWHM H and K images obtained with
the Gemini Mauna Kea telescope. Stars with K = 15.5, which are likely evolving
near the tip of the asymptotic giant branch (AGB), are resolved to within 2
arcsec of the nucleus, and it is concluded that the peak stellar brightness
near the center of M32 is similar to that in the outer regions of the galaxy.
Moreover, the projected density of bright AGB stars follows the visible light
profile to within 2 arcsec of the nucleus, indicating that the brightest stars
are well mixed throughout the galaxy. Thus, there is no evidence for an age
gradient, and the radial variations in spectroscopic indices and ultraviolet
colors that have been detected previously must be due to metallicity and/or
some other parameter. We suggest that either the bright AGB stars formed as
part of a highly uniform and coherent galaxy-wide episode of star formation, or
they originated in a separate system that merged with M32.Comment: 9 pages of text, 3 figures. ApJ (Letters) in pres
Commercial apple industry of New Hampshire, Bulletin, no. 223
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Studies in economics of apple orcharding, Bulletin, no. 257
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Studies in economics of apple orcharding, Bulletin, no. 323
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Studies in economics of apple orcharding, Bulletin, no. 279
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Randomised controlled trial of a Calcium Channel or Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker Regime to Reduce Blood Pressure Variability following Ischaemic Stroke (CAARBS): a protocol for a feasibility study
Introduction Raised blood pressure (BP) is common after stroke and is associated with a poor prognosis, yet trials of BP lowering in the immediate poststroke period have not demonstrated a benefit. One possible explanation for this may be that BP variability (BPV) rather than absolute levels predicts outcome, as BPV is increased after stroke and is associated with poor outcomes. Furthermore, there is evidence of distinct antihypertensive class effects on BPV despite similar BP-lowering effects. However, whether BPV in the immediate poststroke period is a therapeutic target has not been prospectively investigated. The objectives of this trial are to assess the feasibility and safety of recruiting patients following an acute ischaemic stroke or transient ischaemic attack (TIA) to an interventional randomised controlled trial comparing the effects of two different antihypertensive drug classes on BPV. Secondary exploratory objectives are to assess if different therapeutic strategies have diverse effects on levels of BPV and if this has an impact on outcomes. Methods 150 adult patients with first-ever ischaemic stroke or TIA who require antihypertensive therapy for secondary prevention will be recruited within 7 days of the event from stroke services across three sites. After baseline assessments they will be randomly assigned to treatment with a calcium channel blocker or ACE inhibitor/angiotensin receptor blocker-based regimen and followed up for a period of three months. Ethics and dissemination Ethical and regulatory approvals have been granted. Dissemination is planned via publication in peer-reviewed medical journals and presentation at relevant conferences. Trial registration number ISRCTN10853487
The remnant of SN1987A revealed at (sub-)mm wavelengths
Context: Supernova 1987A (SN1987A) exploded in the Large Magellanic Cloud
(LMC). Its proximity and rapid evolution makes it a unique case study of the
early phases in the development of a supernova remnant. One particular aspect
of interest is the possible formation of dust in SN1987A, as SNe could
contribute significantly to the dust seen at high redshifts. Aims: We explore
the properties of SN1987A and its circumburst medium as seen at mm and sub-mm
wavelengths, bridging the gap between extant radio and infrared (IR)
observations of respectively the synchrotron and dust emission. Methods:
SN1987A was observed with the Australia Telescope Compact Array (ATCA) at 3.2
mm in July 2005, and with the Atacama Pathfinder EXperiment (APEX) at 0.87 mm
in May 2007. We present the images and brightness measurements of SN1987A at
these wavelengths for the first time. Results: SN1987A is detected as an
unresolved point source of 11.2 +/- 2.0 mJy at 3.2 mm (5" beam) and 21 +/- 4
mJy at 0.87 mm (18" beam). These flux densities are in perfect agreement with
extrapolations of the powerlaw radio spectrum and modified-blackbody dust
emission, respectively. This places limits on the presence of free-free
emission, which is similar to the expected free-free emission from the ionized
ejecta from SN1987A. Adjacent, fainter emission is observed at 0.87 mm
extending ~0.5' towards the south-west. This could be the impact of the
supernova progenitor's wind when it was still a red supergiant upon a dense
medium. Conclusions: We have established a continuous spectral energy
distribution for the emission from SN1987A and its immediate surroundings,
linking the IR and radio data. This places limits on the contribution from
ionized plasma. Our sub-mm image reveals complexity in the distribution of cold
dust surrounding SN1987A, but leaves room for freshly synthesized dust in the
SN ejecta.Comment: Accepted for publication in Astronomy and Astrophysics Letters on 28
April 2011. A better quality figure 1 can be had from
http://www.astro.keele.ac.uk/~jacco/research/SN1987A087mm.ep
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