985 research outputs found
The health needs of women prisoners: an Italian field survey
Introduction. Health care in prisons represents an important part of public health due to the interaction between prisons and society. Women prisoners have needs that distinguish them from male prisoners, however little is known about how those needs are met. The aim of the study was to gather information about the needs of women in prison and to identify which of their needs are the most or the least met. Methods. This study investigated the needs of detained women using a newly developed Questionnaire based on Gordon’s model. In this descriptive study, data were collected from a onvenient sample of women recruited from two Italian prisons. Data analysis used descriptive statistics. Results. Fifty-five women (response rate = 92%) completed the self-reported questionnaire. Our findings showed that physical needs are met worse than psychological and social needs. The majority of physical needs were related to the inability to meet food preferences and the difficulty in respecting food requirements related to disease and by religion. The women experienced a loss of privacy, and they need more time for improving the quality of their relationships. The majority of the participants (65%) declared that they suffer from psychological disorders with an alarming percentage (29%) stating that they had thoughts of self-harm. They commonly consume tobacco (87.3%), and abuse substances (20%). Discussion and conclusions. The recognition of multi-dimensional women’s needs is of primary importance to create opportunities to support incarcerated women and to build health-promoting gender-sensitive interventions.
Therapeutic Options for the Treatment of Actinic Keratosis with Scalp and Face Localization
Actinic keratosis (AK) is a common skin disease related
to ultraviolet chronic exposure, that is now considered a
squamous cell carcinoma in situ. Primary skin cancer prevention
strategies should be recommended for high risk patients. There
is a wide spectrum of treatment options available for AKs, and
several variables should be taken into account regarding the best
therapeutic choice for each patient. The purpose of this article is
to review the current treatment strategies for AKs localized on
the face and scalp, with a focus on the practical point of view that
could be useful for choosing the best therapeutic option. The two
main therapeutic approaches will be distinguished first: lesiondirected
and field-directed. Afterwards, the treatment based on
clinical type and patient comorbidity will be discussed
Therapeutic Options for the Treatment of Actinic Keratosis with Scalp and Face Localization
Actinic keratosis (AK) is a common skin disease related
to ultraviolet chronic exposure, that is now considered a
squamous cell carcinoma in situ. Primary skin cancer prevention
strategies should be recommended for high risk patients. There
is a wide spectrum of treatment options available for AKs, and
several variables should be taken into account regarding the best
therapeutic choice for each patient. The purpose of this article is
to review the current treatment strategies for AKs localized on
the face and scalp, with a focus on the practical point of view that
could be useful for choosing the best therapeutic option. The two
main therapeutic approaches will be distinguished first: lesiondirected
and field-directed. Afterwards, the treatment based on
clinical type and patient comorbidity will be discussed
Face and scalp basal cell carcinoma treatment: A review of the literature
Basal cell carcinoma (BCC) is the most frequent skin cancer and is characterized by slow growth, even if it can be locally invasive and rarely metastasizes. Many different phenotypic presentations and histopathologic subtypes have been described, and the current guidelines subdivide BCCs into low-risk (nodular and superficial) and high-risk subtypes (micronodular, infiltrating, and morphoeic BCC and those with squamous differentiation). Dermoscopy allows the identification of the features associated with these different subtypes. Compared with the low-risk forms of BCC, more aggressive ones tend to undergo more frequently incomplete surgical excision and perineural invasion, so the identification of these lesions before surgery is extremely important. The gold standard of treatment is surgery, particularly for the H region of the face and infiltrative lesions, but other options are available and selected according to many variables, including body area, age, comorbidities, and clinical, dermoscopic, and histopathological features of the lesion. Moreover, the possible complications of surgical approaches, namely healing defects, failure of skin grafts, and wound infection, should be considered. In this review we discuss the management of BCC localized on the face and scalp, according to the currently available treatment options. </p
Therapeutic Options for the Treatment of Actinic Keratosis with Scalp and Face Localization
Actinic keratosis (AK) is a common skin disease related to ultraviolet chronic exposure, that is now considered a
squamous cell carcinoma in situ. Primary skin cancer prevention
strategies should be recommended for high risk patients. There
is a wide spectrum of treatment options available for AKs, and
several variables should be taken into account regarding the best
therapeutic choice for each patient. The purpose of this article is
to review the current treatment strategies for AKs localized on
the face and scalp, with a focus on the practical point of view that
could be useful for choosing the best therapeutic option. The two
main therapeutic approaches will be distinguished first: lesiondirected and field-directed. Afterwards, the treatment based on
clinical type and patient comorbidity will be discussed
Exploration of ligand binding modes towards the identification of compounds targeting HuR : a combined STD-NMR and Molecular Modelling approach
Post-transcriptional processes have been recognised as pivotal in the control of gene expression,
and impairments in RNA processing are reported in several pathologies (i.e., cancer and
neurodegeneration). Focusing on RNA-binding proteins (RBPs), the involvement of Embryonic Lethal
Abnormal Vision (ELAV) or Hu proteins and their complexes with target mRNAs in the aetiology of
various dysfunctions, has suggested the great potential of compounds able to interfere with the
complex stability as an innovative pharmacological strategy for the treatment of numerous diseases.
Here, we present a rational follow-up investigation of the interaction between ELAV isoform HuR
and structurally-related compounds (i.e., favonoids and coumarins), naturally decorated with
diferent functional groups, by means of STD-NMR and Molecular Modelling. Our results represent
the foundation for the development of potent and selective ligands able to interfere with ELAV–RNA
complexes
Notulae to the Italian flora of algae, bryophytes, fungi and lichens: 3
In this contribution, new data concerning bryophytes, fungi and lichens and of the Italian flora are presented. It includes new records and confirmations for the bryophyte genera Dicranodontium, Fontinalis, Lophocoleaand Riccia, the fungal genus Diplolaeviopsis, the lichen genera Agonimia, Cladonia, Protoparmelia, Rhizocarpon, and Scytinium
Circulating functional T cells specific to human herpes virus 6 (HHV6) antigens in individuals with chromosomally integrated HHV6
Circulating functional T cells specific to human herpes virus 6 (HHV6) antigens in individuals with chromosomally integrated HHV
- …