Structure–property relationship in mechanochemically prepared polyaniline

The comparative analysis of the physicochemical properties of polyaniline prepared in the conditions of solventless mechanochemical treatment in the ball mill (PAni|mch) and polyaniline synthesized by the usual oxidative polymerization in the solvent (PAni|c) is carried out. Conductivity of PAni|mch substantially exceeds that of PAni|c. As molecular weights of PAni|mch and PAni|c are comparable, the observed difference could be connected with the influence of mechanical stress which affects the polymer during its mechanochemical preparation. The increased conductivity of polyaniline obtained by post-synthesis mechanochemical treatment of PAni|c (PAni|mt) confirms such explanation. It could be concluded from the results of the structural investigations as well as of spectral and electrochemical studies that the shear stress which exerts influence on the polymer during mechanochemical synthesis or mechanochemical treatment leads to the increase of the interchain π–π interaction and, consequently, to the efficient improvement of conductivity

2D-BN nanoparticles as a spectroscopic marker and drug delivery system with protection properties

An application of 2D-BN nanoparticles as a spectroscopic marker, weak luminescent marker and anticancer drug (doxorubicin, DOX) delivery system with protection properties was studied for the LNCaP strains of cancer cells using FTIR and Raman spectroscopy for analysing the cancer cells, cells with BN, the cancer cells with DOX, and the cancer cells with BN nanoparticles loaded by DOX. Study of IR absorption and Raman spectra of the LNCaP strains of cancer cells incubated with 2D-BN nanoparticles for 1 hour showed that the 2D-BN nanoparticles could pass through the cell membrane and localize inside the membrane or close to the membrane in the cytoplasm of the cells. We registered the spectra of the disturbed lipids during the DOX-2D-BN passing through the membrane. After incubation for 2 hours and more, spectral changes in other structural components of the cell (nuclei, cytoplasm, mitochondria) can be registered. Confocal microscopy showed that a gold nanostructured support enhances the fluorescence of the cancer cells with 2D-BN as well as that with DOX, however the double action of 2D-BN and DOX on the cancer cells aggravates the emission property of the studied system. An MTT test showed that the toxicity of DOX on the 2D-BN nanoparticles is less than that on the reference cells, and at the same time the efficiency of the DOX action on the cancer cells does not change