Análise de episódios de ensino : articulando os discursos teórico e prático na formação de professores

O presente trabalho apresenta a estrutura de uma disciplina de prática de ensino que está fundamentada na matriz sociocultural. A ação mediada é sugerida na disciplina como uma construção teórica que permite desenvolver um modelo de organização do ensino, no qual o professor se oriente para planejar suas aulas. O modelo topológico de ensino é uma ferramenta metodológica derivada da teoria da ação mediada que julgamos capaz de subsidiar a organização do ensino no cotidiano da sala de aula e em diferentes estágios da vida escolar. Para caracterizar o domínio e apropriação das diferentes ferramentas culturais utilizadas pelos professores, quando esses planejam e analisam as sequências de ensino, coletamos dados em questionários, registro audiovisual das aulas e relatórios individuais. Dados de resposta a um questionário são apresentados e analisados neste trabalho

Testing the universality of free fall with rubidium and ytterbium in a very large baseline atom interferometer

We propose a very long baseline atom interferometer test of Einstein's equivalence principle (EEP) with ytterbium and rubidium extending over 10m of free fall. In view of existing parametrizations of EEP violations, this choice of test masses significantly broadens the scope of atom interferometric EEP tests with respect to other performed or proposed tests by comparing two elements with high atomic numbers. In a first step, our experimental scheme will allow reaching an accuracy in the E\"otv\"os ratio of $7\times 10^{-13}$. This achievement will constrain violation scenarios beyond our present knowledge and will represent an important milestone for exploring a variety of schemes for further improvements of the tests as outlined in the paper. We will discuss the technical realisation in the new infrastructure of the Hanover Institute of Technology (HITec) and give a short overview of the requirements to reach this accuracy. The experiment will demonstrate a variety of techniques which will be employed in future tests of EEP, high accuracy gravimetry and gravity-gradiometry. It includes operation of a force sensitive atom interferometer with an alkaline earth like element in free fall, beam splitting over macroscopic distances and novel source concepts

Contrast-enhanced mammography-guided biopsy: technical feasibility and first outcomes

Objectives To evaluate the feasibility of contrast-enhanced mammography (CEM)-guided biopsy at Hospital del Mar, a Spanish university hospital. Methods We retrospectively reviewed all consecutive women with a suspicious enhancing finding eligible for CEM-guided biopsy, who were prospectively enrolled in a pre-marketing clinical validation and feasibility study (October 2019 to September 2021). CEM-guided biopsy is a stereotactic-based procedure that, by using intravenous iodinated contrast media administration and dual-energy acquisition, provides localisation of enhancing lesions. All the biopsies were performed using a vacuum-assisted device. We collected procedural characteristics (patient position and type of approach), and histopathological results. Feasibility endpoints included success (visualisation of the enhancing lesion, post-procedural biopsy changes and clip placement), procedural time, number of scout acquisitions and complications. Results A total of 66 suspicious enhancing lesions (18.0% foci, 44.0% mass, 38.0% non-mass enhancement; median size 8.5 mm) in 64 patients (median age 59 years, mostly minimal [48.4%] or mild [32.8%] background parenchymal enhancement) were referred for CEM-guided biopsy in the study period. The success rate was 63/66 (95.4%). Amongst successful procedures, patients were most frequently seated (52/63, 82.5%) and the preferred approach was horizontal (48/63, 76.2%). Median total time per procedure was 15 min. Median number of acquisitions needed before targeting was 2 (range 1-4). Complications consisted of hematoma (17/63, 27%) and vasovagal reaction (2/63, 3.2%). At histology, the malignancy rate was 25/63 (39.7%). Conclusion In this first patient series, CEM-guided breast biopsy was feasible, with success and complication rates similar to those previously reported for magnetic resonance guidance

Quality of life and cost-effectiveness analysis of topical tranexamic acid and fibrin glue in femur fracture surgery

Altres ajuts: European Regional Development Fund (FEDER); MAPFRE Foundation (grant code SA/12/AYU/456).Background: We assessed quality of life (QoL) of patients undergoing surgery for proximal femur fracture and performed a cost-effectiveness analysis of haemostatic drugs for reducing postoperative bleeding. Methods: We analysed data from an open, multicentre, parallel, randomized controlled clinical trial (RCT) that assessed the efficacy and safety of tranexamic acid (TXA group) and fibrin glue (FG group) administered topically prior to surgical closure, compared with usual haemostasis methods (control group). For this study we conducted a cost-effectiveness analysis of these interventions from the Spanish Health System perspective, using a time horizon of 12 months. The cost was reported i

Políticas de país y logros de regiones: el caso de la calidad de la educación secundaria en Colombia

Este documento usa el test de Phillips and Sul (2009) para evaluar la hipótesis de convergencia en el logro educativo de los colegios públicos y privados, a nivel municipal y para el período 1980-2014. Aunque los principios que dictaminan la provisión de educación pública son homogéneos en todo el país, el logro educativo de los diferentes municipios no evidencia patrones de convergencia global. No obstante, se establece la presencia de seis clubes de convergencia. Los primeros dos clubes, los cuales incluyen los municipios con mejor desempeño, están desproporcionalmente representados por colegios privados en las principales áreas metropolitanas del país, mientras que los últimos tres clubes están compuestos principalmente por colegios públicos localizados en el litoral Pacífico y la región Caribe

Mapping the Sites of Putative Tumor Suppressor Genes at 6p25 and 6p21.3 in Cervical Carcinoma: Occurrence of Allelic Deletions in Precancerous Lesions

Allelic deletions on the short arm of chromosome 6 (6p) are one of the common, possibly early, genetic changes that occur in the pathogenesis of cervical carcinoma (CC). Previous loss of heterozygosity (LOH) studies in CC identified a number of critical regions of deletions on 6p. However, the precise location of minimally deleted regions and their role in precancer- ous lesions have not been well characterized. To address these questions, we first performed a detailed LOH analysis on 6p in 59 cases of invasive CC. The pattern of LOH identified two minimal regions of deletions, one spanning a 5 cM genetic distance at 6p25 and a second site of 10.3 cM deletion mapping to 6p21.3. The 6p21.3 minimal deletion spans HLA class I genes. To understand the role of 6p genetic alterations in the develop- ment of CC, we also investigated 12 high-grade and 4 low-grade cases of cervical intraepithelial neoplasia (CIN) for LOH after laser microdissec- tion. The high-grade CINs exhibited 91.7% LOH, and low-grade CINs had 50% LOH. These findings implicate the presence of at least two tumor suppressor genes on 6p relevant to CC and suggest that these genetic alterations occur very early in CC development. This study should there- fore facilitate the identification of tumor suppressor genes on 6p and may identify which CINs are at high risk of progressing to invasive CC

Políticas de país e conquistas regionais: o caso da qualidade do ensino médio na Colômbia

This document uses the Phillips and Sul (2009) test to assess the hypothesis of convergence on educational achievement of public and private schools, at the municipal level, for the period 1980-2014. Even though the normativity and provision of public education is homogeneous across the country, we find that the educational attainment of the municipalities do not show evidence of global convergence. However, we find the existence of six convergence clubs. The first two clubs, which include the municipalities with the best performance, are mainly private institutions in the major metropolitan areas, while the latter three clubs are composed primarily for public institutions located on the Pacific coast and in the Caribbean region.Este documento usa el test de Phillips and Sul (2009) para evaluar la hipótesis de convergencia en el logro educativo de los colegios públicos y privados, a nivel municipal y para el período 1980-2014. Aunque los principios que dictaminan la provisión de educación pública son homogéneos en todo el país, el logro educativo de los diferentes municipios no evidencia patrones de convergencia global. No obstante, se establece la presencia de seis clubes de convergencia. Los primeros dos clubes, los cuales incluyen los municipios con mejor desempeño, están desproporcionalmente representados por colegios privados en las principales áreas metropolitanas del país, mientras que los últimos tres clubes están compuestos principalmente por colegios públicos localizados en el litoral Pacífico y la región Caribe.Este documento utiliza o teste de Phillips e Sul (2009) para avaliar a hipótese de convergência no desempenho educacional de escolas públicas e privadas, em nível municipal e para o período 1980-2014. Embora os princípios que regem a oferta de educação pública sejam homogêneos em todo o país, o desempenho educacional dos diferentes municípios não apresenta padrões de convergência global. No entanto, está estabelecida a presença de seis clubes de convergência. Os dois primeiros clubes, que incluem os municípios de melhor desempenho, são desproporcionalmente representados por escolas particulares nas principais áreas metropolitanas do país, enquanto os três últimos clubes são compostos principalmente por escolas públicas localizadas na costa do Pacífico e na região do Caribe