The quantum maxima for the basic graphs of exclusivity are not reachable in Bell scenarios

A necessary condition for the probabilities of a set of events to exhibit Bell nonlocality or Kochen-Specker contextuality is that the graph of exclusivity of the events contains induced odd cycles with five or more vertices, called odd holes, or their complements, called odd antiholes. From this perspective, events whose graph of exclusivity are odd holes or antiholes are the building blocks of contextuality. For any odd hole or antihole, any assignment of probabilities allowed by quantum mechanics can be achieved in specific contextuality scenarios. However, here we prove that, for any odd hole, the probabilities that attain the quantum maxima cannot be achieved in Bell scenarios. We also prove it for the simplest odd antiholes. This leads us to the conjecture that the quantum maxima for any of the building blocks cannot be achieved in Bell scenarios. This result sheds light on why the problem of whether a probability assignment is quantum is decidable, while whether a probability assignment within a given Bell scenario is quantum is, in general, undecidable. This also helps to undertand why identifying principles for quantum correlations is simpler when we start by identifying principles for quantum sets of probabilities defined with no reference to specific scenarios.Comment: 8 pages, 4 figure

Forensic genetic analysis of South Portuguese population with the six dye Powerplex® Fusion 6C

Poster apresentado no 28th Congress of International Society For Forensic Genetics (ISFG 2019), Praga, República Checa, 9-13 de Setembro de 2019As an improvement in efficiency and in Human Discrimination Power, the new six dye multiplex kit PowerPlex® Fusion 6C System, by Promega, available for human identification can co-amplify 27 loci, in a single reaction, have been introduced in the last years with great success. This kit allows the amplification and detection of autosomal loci included in the expanded Combined DNA Index System CODIS, plus the loci Penta D, PENTA E and SE33 as well as Amelogenin for gender determination. Furthermore, this kit includes three Y –STRs (DYS391, DYS576 and DYS570), allowing allelic attribution in a total of 27 loci. This genetic markers extension satisfies not only CODIS but also European Standard Set recommendations. Thinking about continuous human migration movements, especially in a very cosmopolitan region like Lisbon and south of Portugal, and also, in keeping population studies and actualized STR databases we decided to update our previous studies. Our sample is composed of 600 unrelated individuals, from paternity testing with laboratory identity anonymised. DNA was extracted by Prep-n-go BufferTM(Thermo-Fisher Scientific). PCR amplification was performed with PowerPlex® Fusion 6C System, according to manufacturer’s guidelines. Fragment analysis was carried out in an Applied Biosystems® 3500 Genetic Analyser. Electrophoresis results were analysed with GeneMapper® ID-X v1.4. Allele frequencies and population statistics, including Hardy-Weinberg equilibrium p-values from exact test probabilities and forensic parameters were calculated with adequate software. In conclusion, our population information was updated in order to apply most recent data in our casework weight of evidence.N/

QUANTIFILER®TRIO DNA method performance in a collection of ancient samples

Trabalho científico apresentado sob a forma de Poster no evento 9th ISABS Conference on Forensic Anthropologic Genetics and Mayo Clinicm Bol, Island of Brac, Croacia, 2015During the past few years significant progress has been made in solving technical challenges associated with STR profiling including the ability to analyze degraded DNA and low amounts of DNA. The result of these changes is that useful STR profiles can now be obtained from previously untypeable forensic DNA samples. Analysis of DNA from ancient material represents an important role in molecular anthropology, although there are many limitations concerning low DNA quantity and/or degraded DNA, and/or PCR inhibitors. These factors can make it difficult to decide whether to continue with STR analysis, which STR panel to use and how much DNA to add to PCR reaction. With all these constraints, DNA quantification represents an important tool to decide which method will follow in order to improve workflow and have good results in less time-consuming. The Quantifiler® Trio DNA method provides a quality index (QI) to detect the presence of degraded DNA along with PCR inhibitors.This guide allows the selection of the optimal short tandem repeat (STR) analysis chemistry (autosomal, or miniSTR) and streamlines the workflow while increasing downstream analysis success rates. In order to compare DNA quality from different extraction methods, samples from 46 exhumed Middle Ages individuals were extracted with modified phenol-chloroform method and also PrepFiler Express BTA™ method. DNA was quantified with Quantifiler® Trio DNA Quantification in an Applied Biosystems® 7500 Real-Time PCR System. Results were analyzed and allow us to point Quantifiler® Trio method as an important tool in pre-STR typing methods in ancient samplesN/

Digestibilidade aparente dos nutrientes do feno da erva sal (Atriplex nummularia Lindl.) em caprinos e ovinos.

Foram avaliafdos os coeficientes de digestibilidade aparente dos nutrientes em dieta exclusiva do feno de erva sal (Atriplex nummularia Lindl.). Foram utilizados 12 animais, sendo seis caprinos e seis ovinos, todos machos, com peso vivo médio inicial de 18 kg. Todos os animais foram alojados em gaiolas de metabolismo, com livre acesso à água e sal mineral, durante um período de 15 dias, sendo 10 de adaptação e cinco de coleta de fezes. A análise de variância não apresentou diferença estatística (P>0,05) quanto à digestibilidade da matéria seca, proteína bruta, fibra em detergente neutro, matéria orgânica, matéria mineral, extrato etéreo e carboidratos totais em função de ambas as espécies. Enquanto que para a digestibilidade da fibra em detergente ácido, houve diferença (P<0,05), mostrando dessa forma, igual capacidade para fazer uso os nutrientes do feno da erva sal

Avaliação cognitiva, comportamental e funcional : doença de Alzheimer

A review of the evidence on cognitive, functional and behavioral assessment for the diagnosis of dementia due to Alzheimer’s disease (AD) is presented with revision and broadening of the recommendations on the use of tests and batteries in Brazil for the diagnosis of dementia due to AD. A systematic review of the literature (MEDLINE, LILACS and SCIELO database) was carried out by a panel of experts. Studies on the validation and/or adaptation of tests, scales and batteries for the Brazilian population were analyzed and classified according to level of evidence. There were sufficient data to recommend the IQCODE, DAFS-R, DAD, ADL-Q and Bayer scale for the evaluation of instrumental activities of daily living, and the Katz scale for the assessment of basic activities of daily living. For the evaluation of neuropsychiatric symptoms, the Neuropsychiatric Inventory (NPI) and the CAMDEX were found to be useful, as was the Cornell scale for depression in dementia. The MiniMental State Examination has clinical utility as a screening test, as do the multifunctional batteries (CAMCOG-R, ADAS-COG, CERAD and MDRS) for brief evaluations of several cognitive domains. There was sufficient evidence to recommend the CDR scale for clinical and severity assessment of dementia. Tests for Brazilian Portuguese are recommended by cognitive domain based on available data.Este artigo apresenta revisão e ampliação das recomendações sobre os testes e baterias empregados no Brasil para o diagnóstico e avaliação cognitiva, funcional e comportamental da demência na doença de Alzheimer (DA). De modo sistemático foi revista a literatura disponível (nas bases MEDLINE, LILACS e SCIELO) e os artigos foram avaliados e classificados por níveis de evidência, para se estabelecerem as recomendações. Para a avaliação funcional a recomendação é o uso das escalas IQCODE, DAFS-R, DAD, ADL-Q e Bayer para avaliação das atividades instrumentais da vida diária e escala Katz para avaliação das atividades básicas. Para avaliação dos sintomas neuropsiquiátricos foram recomendadas as escalas NPI e CAMDEX e a Cornell para depressão em demência. Como instrumento de rastreio deve-se utilizar o Mini-Exame do Estado Mental; quanto às baterias multifuncionais, pode-se aplicar CAMCOG-R, ADAS-COG, CERAD e MDRS, que avaliam brevemente várias funções cognitivas. Para avaliação clínica da demência e classificação de acordo com a gravidade é recomendada a escala CDR. São recomendados os testes por domínio cognitivo baseados nas evidências disponíveis para uso na nossa língua

Abundances of Mn, Co and Eu in a sample of 20 F-G disk stars: the influence of hyperfine structure splitting

We present Mn, Co and Eu abundances for a sample of 20 disk F and G dwarfs and subgiants with metallicities in the range -0.8 <= [Fe/H] <= +0.3. We investigate the influence of hyperfine structure (HFS) on the derived abundances of Mn and Co by using HFS data from different sources in the literature, as well as calculated HFS from interaction factors A and B. Eu abundances were obtained from spectral synthesis of one Eu II line that takes into account HFS from a series of recent laboratory measurements. For the lines analyzed in this study, we find that for manganese, the differences between abundances obtained with different HFSs are no larger than 0.10 dex. Our cobalt abundances are even less sensitive to the choice of HFS than Mn, presenting a 0.07 dex maximum difference between determinations with different HFSs. However, the cobalt HFS data from different sources are significantly different. Our abundance results for Mn offer an independent confirmation of the results from Prochaska & McWilliam (2000), who favour type Ia supernovae as the main nucleosynthesis site of Mn production, in contrast to trends of Mn versus metallicity previously reported in the literature. For Co, we obtain [Co/Fe] ~ 0.0 in the range -0.3 < [Fe/H] < +0.3 and [Co/Fe] rising to a level of +0.2 when [Fe/H] decreases from -0.3 to -0.8, in disagreement with recent results in the literature. The observed discrepancies may be attributed to the lack of HFS in the works we used for comparison. Our results for Eu are in accordance with low-mass type II supernovae being the main site of the r-process nucleosynthesis.Comment: 8 pages, 6 Postscript figures, accepted for publication in Astronomy & Astrophysic