2 nd Brazilian Consensus on Chagas Disease, 2015

Abstract Chagas disease is a neglected chronic condition with a high burden of morbidity and mortality. It has considerable psychological, social, and economic impacts. The disease represents a significant public health issue in Brazil, with different regional patterns. This document presents the evidence that resulted in the Brazilian Consensus on Chagas Disease. The objective was to review and standardize strategies for diagnosis, treatment, prevention, and control of Chagas disease in the country, based on the available scientific evidence. The consensus is based on the articulation and strategic contribution of renowned Brazilian experts with knowledge and experience on various aspects of the disease. It is the result of a close collaboration between the Brazilian Society of Tropical Medicine and the Ministry of Health. It is hoped that this document will strengthen the development of integrated actions against Chagas disease in the country, focusing on epidemiology, management, comprehensive care (including families and communities), communication, information, education, and research

Plasma lipid profiles discriminate bacterial from viral infection in febrile children

Fever is the most common reason that children present to Emergency Departments. Clinical signs and symptoms suggestive of bacterial infection ar

Letras y Encajes

Letras y Encajes publica su primer número en 1926; esta revista fue fundada por mujeres de la clase dirigente de Medellín, muchas de ellas socias de la institución cultural Centro Femenino de Estudios (Sofía Ospina de Navarro, Teresa Santamaría de González, Ángela Villa de Toro y Alicia Merizalde de Echavarría), a lo largo del tiempo se consolidó como la revista femenina más importante del país, dirigida a mujeres de la clase alta y media, abordaba temas que giraban alrededor del hogar, la religión, la literatura y la moda de la época. La revista circuló mensualmente hasta 1959. Sus principales redactoras eran mujeres, pero contaba con la colaboración ocasional de algunos hombres y con traducciones de autoras y autores extranjeras

Política cultural e desenvolvimento: uma análise do Programa Bairro Escola, do município de Nova Iguaçu - Rio de Janeiro

O objetivo do trabalho é identificar de que maneira as práticas atuais do Programa Bairro Escola, da Prefeitura de Nova Iguaçu, no Estado do Rio de Janeiro, atendem aos objetivos de desenvolvimento estipulados em sua origem. O programa funciona a partir de parcerias e busca a educação em turno integral, associando oficinas de cultura e esporte com atividades de reforço escolar. Adotou-se como conceito de cultura as manifestações culturais formalmente organizadas e institucionalizadas. No que diz respeito ao conceito de desenvolvimento, tomou-se como base as ideias de Furtado (1984), pensando-se o desenvolvimento como um conceito pautado em fins substantivos, e não apenas em fatores econômicos. A relação entre cultura e desenvolvimento é baseada em Santos (2008) e Furtado (1984), onde a cultura é fonte criativa para um processo endógeno de desenvolvimento. Foram coletados dados primários e secundários. Para sua análise, foram criados indicadores originários das categorias: cultura, desenvolvimento e a relação entre cultura e desenvolvimento. Há indícios de que o programa Bairro Escola não está mais funcionando da forma como foi planejado, principalmente por falta de recursos e de infraestrutura. Pode ser observada ainda uma diferença marcante entre o discurso dos entrevistados que trabalham nas escolas, e o discurso oficial. Indo ao encontro de Furtado (1984), o caso do Programa Bairro Escola ilustra que muitos obstáculos à liberdade criativa ainda precisam ser removidos para que a relação entre cultura e desenvolvimento se dê de forma plena

Many Labs 2: Investigating Variation in Replicability Across Samples and Settings

We conducted preregistered replications of 28 classic and contemporary published findings, with protocols that were peer reviewed in advance, to examine variation in effect magnitudes across samples and settings. Each protocol was administered to approximately half of 125 samples that comprised 15,305 participants from 36 countries and territories. Using the conventional criterion of statistical significance (p < .05), we found that 15 (54%) of the replications provided evidence of a statistically significant effect in the same direction as the original finding. With a strict significance criterion (p < .0001), 14 (50%) of the replications still provided such evidence, a reflection of the extremely high-powered design. Seven (25%) of the replications yielded effect sizes larger than the original ones, and 21 (75%) yielded effect sizes smaller than the original ones. The median comparable Cohen’s ds were 0.60 for the original findings and 0.15 for the replications. The effect sizes were small (< 0.20) in 16 of the replications (57%), and 9 effects (32%) were in the direction opposite the direction of the original effect. Across settings, the Q statistic indicated significant heterogeneity in 11 (39%) of the replication effects, and most of those were among the findings with the largest overall effect sizes; only 1 effect that was near zero in the aggregate showed significant heterogeneity according to this measure. Only 1 effect had a tau value greater than .20, an indication of moderate heterogeneity. Eight others had tau values near or slightly above .10, an indication of slight heterogeneity. Moderation tests indicated that very little heterogeneity was attributable to the order in which the tasks were performed or whether the tasks were administered in lab versus online. Exploratory comparisons revealed little heterogeneity between Western, educated, industrialized, rich, and democratic (WEIRD) cultures and less WEIRD cultures (i.e., cultures with relatively high and low WEIRDness scores, respectively). Cumulatively, variability in the observed effect sizes was attributable more to the effect being studied than to the sample or setting in which it was studied