Introduction to ecotechnological solutions

International audienceThis chapter concludes the work presented in this book. Future research topics are proposed which include suggestions for developing a database of plant species useful for erosion control and slope stability. Decision support systems also need more work and should be available for the general practitioner to use without specialist training. Field studies and numerical modelling should be combined to answer specific questions, especially concerning large-scale slope instability problems. As economics is an important factor to consider, more research into vegetating hotspots only should be performed. Finally, in today’s changing climate, carbon sequestration through vegetation strategies could also be an important line of researc

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

The function of p53 as a tumour suppressor has been attributed to its ability to promote cell death or permanently inhibit cell proliferation. However, in recent years, it has become clear that p53 can also contribute to cell survival. p53 regulates various metabolic pathways, helping to balance glycolysis and oxidative phosphorylation, limiting the production of reactive oxygen species, and contributing to the ability of cells to adapt to and survive mild metabolic stresses. Although these activities may be integrated into the tumour suppressive functions of p53, deregulation of some elements of the p53-induced response might also provide tumours with a survival advantage