Constructing deal networks : brokers as network 'architects' in the U.S. IPO market and other examples.

We introduce the concept of the network architect to extend theory explaining how brokers create and manage structural holes in mediated markets. We argue that a broker's social resources and dependence on the market, along with exogenous deal conditions, influence the broker's motivations and willingness to make tradeoffs between long-term and short-term considerations when constructing deal networks. We develop our model and propositions in the context of the U.S. initial public offerings market and then generalize these arguments to other market contexts

How do liquids confined at the nanoscale influence adhesion?

Liquids play an important role in adhesion and sliding friction. They behave as lubricants in human bodies especially in the joints. However, in many biological attachment systems they acts like adhesives, e.g. facilitating insects to move on ceilings or vertical walls. Here we use molecular dynamics to study how liquids confined at the nanoscale influence the adhesion between solid bodies with smooth and rough surfaces. We show that a monolayer of liquid may strongly affect the adhesion.Comment: 5 pages, 9 color figures. Some figures are in Postscript Level 3 format. Minimal changes with respect to the previous version. Added doi and reference to the published article also inside the pape

Development of quantum perspectives in modern physics

Introductory undergraduate courses in classical physics stress a perspective that can be characterized as realist; from this perspective, all physical properties of a classical system can be simultaneously specified and thus determined at all future times. Such a perspective can be problematic for introductory quantum physics students, who must develop new perspectives in order to properly interpret what it means to have knowledge of quantum systems. We document this evolution in student thinking in part through pre- and post-instruction evaluations using the Colorado Learning Attitudes about Science Survey. We further characterize variations in student epistemic and ontological commitments by examining responses to two essay questions, coupled with responses to supplemental quantum attitude statements. We find that, after instruction in modern physics, many students are still exhibiting a realist perspective in contexts where a quantum-mechanical perspective is needed. We further find that this effect can be significantly influenced by instruction, where we observe variations for courses with differing learning goals. We also note that students generally do not employ either a realist or a quantum perspective in a consistent manner.Comment: 18 pages, plus references; 3 figures; 9 tables. PACS: 01.40.Fk, 03.65._

Variation in Shrinkage Properties of Second-Growth Baldcypress and Tupelo-Gum

Trees of baldcypress and tupelo-gum aged from 55 to 75 years, growing in a naturally regenerated stand in the Atchafalaya Basin in south Louisiana, were felled to provide samples for determination of shrinkage, specific gravity, and extractive content. Samples were taken from six heights and from three radial positions (=wood-types) along three radii. Differences among trees and among plots (which had different basal areas) were found for all measured variables. There were also variations in unextracted specific gravity with height in the tree and wood-type in baldcypress, and, except for specific gravity, with wood-type in tupelo-gum. After extraction, shrinkage effects of height and wood-type were reduced or disappeared. Specific gravity was generally lowest in the lower portion of the stem and in the outerwood. Correlation of shrinkage with specific gravity was highest in the outerwood, and extractive content was correlated with shrinkage in tupelo-gum but not in baldcypress

The EXOSAT medium-energy slew survey catalog

We present a catalog of X-ray sources observed during slew maneuvers by the Medium Energy Detector Array onboard the EXOSAT Observatory. The EXOSAT Medium Energy slew-survey catalog (EXMS) provides a unique record of the 1--8 keV X-ray sky between 1983 and 1986. 98% of the sky was observed, with 85% receiving an exposure of >60 s. 1210 sources were detected. By comparing these source positions with other catalogs, identifications are given for 992 detections (82% of the sample). These identifications consist of 250 distinct objects, including 95 different X-ray binary systems, and 14 different AGN. A further 58 detections have multiple candidates, while 160 detections remain unidentified. Collimator transmission corrected 1-8 keV count rates are given for the identified sources, together with raw count rates for the other detections. The construction of the EXMS and the checks performed to ensure the validity of the derived source properties are discussed. A publically available version of this catalog is maintained on the EXOSAT database and archive system (telnet://[email protected]).Comment: 52 pages. 22 Figures. To be published in A&AS. For more information, see http://astro.estec.esa.nl/SA-general/Projects/Exosat/exmsintro.htm

Peripheral T cell lymphopenia in COVID-19: potential mechanisms and impact

Immunopathogenesis involving T lymphocytes, which play a key role in defence against viral infection, could contribute to the spectrum of COVID-19 disease and provide an avenue for treatment. To address this question, are view of clinical observational studies and autopsy data in English and Chinese languages was conducted with a search of registered clinical trials. Peripheral lymphopenia affecting CD4 and CD8 T cells was a striking feature of severe COVID-19 compared with non-severe disease. Autopsy data demonstrated infiltration of T cells into organs, particularly the lung. 74 clinical trials are on-going that could target T cell-related pathogenesis, particularly IL-6 pathways. SARS-CoV-2 infection interrupts T cell circulation in patients with severe COVID-19. This could be due to redistribution of T cells into infected organs, activation induced exhaustion, apoptosis or pyroptosis. Measuring T cell dynamics during COVID-19 will inform clinical risk-stratification of hospitalised patients and could identify those who would benefit most from 66treatments that target T cell