30 research outputs found

    Impact of Study Skills and Parent Education on First-Year GPA Among College Students With and Without ADHD: A Moderated Mediation Model

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    Objective: To test if the relationship between ADHD and academic achievement is mediated by service utilization and/or study skills, and if these mediation effects are moderated by parental education level. Method: A bootstrapping method within structural equation modeling was used with data from 355 first year college students meeting strict criteria for ADHD or clearly without ADHD to test the mediation and moderation effects. Results: Study skills, but not service utilization, significantly mediated the relationship between ADHD status and GPA; however, this relationship was not significant among students with at least one parent holding a master’s degree or higher. Conclusion: Among first year college students study skills may be a more salient predictor of educational outcomes relative to ADHD status. Additional research into support services for college students with ADHD is needed, however, results suggest interventions targeting study skills may hold particular promise for these students

    Dataset associated with "Seeking congruity for agentic women: a longitudinal examination of college women's persistence in STEM"

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    Those interested in using these data are encouraged to contact Dr. Paul Hernandez ([email protected]) and Dr. Emily Fischer ([email protected]) for more information. Data Contacts: Paul R. Hernandez (primary), [email protected], 979-464-9229 Emily V. Fischer, [email protected], 970-491-8587.Survey data were collected via the online Qualtrics survey system twice yearly in the fall and spring semesters from fall 2015 through spring 2019. This repository contains the data file associated with all surveys utilized in the analyses presented in this research article.Format of Data Files: Data files are in .csv format. Files can be opened by most software (e.g., Notepad, WordPad, Excel) – anything that can read a comma delimited ASCII text file. Here, the file name is "Dataset." In addition, a codebook accompanies the data file. The codebook contains the variable names, variable labels, and value labels for all variables contained within the "Dataset.csv" file.An abundance of literature has examined barriers to women's equal representation in science, technology, engineering, and math (STEM) fields, with many studies showing that STEM fields are not perceived to afford communal goals, a key component of women's interest in future careers. Using Goal Congruity Theory as a framework, we tested the longitudinal impact of perceptions of STEM career goal affordances, communal and agentic goals, and their congruity on persistence in science from the second through fourth years of college among women in STEM majors. We found that women's intent to persist in science were highest in fall of their second year, that persistence intentions exhibited a sharp decline, and that eventually leveled off by their fourth year of college. This pattern was moderated by perceptions of agentic affordances in STEM, such that women with higher perceptions of agentic affordances experienced smaller declines. Similar to prior research, we found that higher perceptions of communal goal affordances in STEM consistently predicted higher persistence intentions. Finally, we found an agentic goal-affordance congruity interaction, such that higher perceptions of agentic affordances in STEM predicted higher persistence intentions; however, the positive relationship was stronger for women with higher agentic goals. We conclude that because STEM fields are stereotyped as affording agentic goals, women who identify interest in a STEM major during their first year of college may be drawn to these fields for this reason, and may benefit from perceptions that STEM affords both communal and agentic goals.Funding for this work was provided by the National Science Foundation through grant number DUE- 1431795, DUE-1431823, and DUE-1460229

    Role modeling is a viable retention strategy for undergraduate women in the geosciences

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    Gender diversity leads to better science; however, a number of science, technology, engineering, and mathematics (STEM) disciplines, including many geoscience subdisciplines, show a persistent gender gap. PROmoting Geo- science Research, Education, and SuccesS (PROGRESS) is a theory-driven role modeling and mentoring program aimed at supporting undergraduate women interested in geoscience-related degree and career pathways. This study is unique because it is being conducted in a long-term applied setting, rather than as a laboratory exercise. We compare female STEM majors in PROGRESS to a matched control group (N = 380) using a longitudinal prospec- tive multisite quasi-experimental design. College women in PROGRESS par- ticipated in a mentoring and role-modeling weekend workshop with follow- up support, while women in the control group participated in neither the workshop nor the follow-up support. PROGRESS members identified more female STEM career role models than controls (60% versus 42%, respectively), suggesting that deliberate interventions can develop the networks of under- graduate women. Undergraduate women that participate in PROGRESS have higher rates of persistence in geoscience-related majors (95% versus 73%), although the rates of switching into a geoscience-related major did not differ across groups. More strikingly, we also find that the persistence of undergrad- uate women in geoscience-related majors is related to the number of female STEM career role models they identify, as their odds of persisting approxi- mately doubles for each role model they identify. We conclude that our ability to retain undergraduate women in the geosciences will depend, in part, on helping them to identify same-gender career role models. Further, the suc- cess of PROGRESS points to steps universities and departments can take to sustain their students’ interest and persistence, such as hosting interactive panels with diverse female scientists to promote the attainability and social relevance of geoscience careers

    31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016) : part two

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    Background The immunological escape of tumors represents one of the main ob- stacles to the treatment of malignancies. The blockade of PD-1 or CTLA-4 receptors represented a milestone in the history of immunotherapy. However, immune checkpoint inhibitors seem to be effective in specific cohorts of patients. It has been proposed that their efficacy relies on the presence of an immunological response. Thus, we hypothesized that disruption of the PD-L1/PD-1 axis would synergize with our oncolytic vaccine platform PeptiCRAd. Methods We used murine B16OVA in vivo tumor models and flow cytometry analysis to investigate the immunological background. Results First, we found that high-burden B16OVA tumors were refractory to combination immunotherapy. However, with a more aggressive schedule, tumors with a lower burden were more susceptible to the combination of PeptiCRAd and PD-L1 blockade. The therapy signifi- cantly increased the median survival of mice (Fig. 7). Interestingly, the reduced growth of contralaterally injected B16F10 cells sug- gested the presence of a long lasting immunological memory also against non-targeted antigens. Concerning the functional state of tumor infiltrating lymphocytes (TILs), we found that all the immune therapies would enhance the percentage of activated (PD-1pos TIM- 3neg) T lymphocytes and reduce the amount of exhausted (PD-1pos TIM-3pos) cells compared to placebo. As expected, we found that PeptiCRAd monotherapy could increase the number of antigen spe- cific CD8+ T cells compared to other treatments. However, only the combination with PD-L1 blockade could significantly increase the ra- tio between activated and exhausted pentamer positive cells (p= 0.0058), suggesting that by disrupting the PD-1/PD-L1 axis we could decrease the amount of dysfunctional antigen specific T cells. We ob- served that the anatomical location deeply influenced the state of CD4+ and CD8+ T lymphocytes. In fact, TIM-3 expression was in- creased by 2 fold on TILs compared to splenic and lymphoid T cells. In the CD8+ compartment, the expression of PD-1 on the surface seemed to be restricted to the tumor micro-environment, while CD4 + T cells had a high expression of PD-1 also in lymphoid organs. Interestingly, we found that the levels of PD-1 were significantly higher on CD8+ T cells than on CD4+ T cells into the tumor micro- environment (p < 0.0001). Conclusions In conclusion, we demonstrated that the efficacy of immune check- point inhibitors might be strongly enhanced by their combination with cancer vaccines. PeptiCRAd was able to increase the number of antigen-specific T cells and PD-L1 blockade prevented their exhaus- tion, resulting in long-lasting immunological memory and increased median survival

    Evaluating the U.S. Estuary Restoration Act to inform restoration policy implementation: A case study focusing on oyster reef projects

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    Recent research revealing the extent of marine habitat degradation has ignited a surge of restoration efforts globally. Restoration of estuarine habitats became a priority in the United States with the Estuary Restoration Act (ERA) of 2000. In the present study, a synthesis of data from the National Estuaries Restoration Inventory (NERI), developed in response to ERA requirements to track and disseminate project data, was conducted in order to analyze U.S. oyster reef restoration efforts. From 2000–2011, more than 45millionwasinvestedin187projectstorestoreover150haofoysterreefhabitat,withprojectsmostheavilyconcentratedintheChesapeakeBayareaandFloridaGulfcoast.Trendsovertimeindicatethatprojectsarebeingimplementedatlargerscales,increasingfromanaverageoflessthan0.4hain2000toover1haonaveragein2011.Costsperunitdecreasedfromanaverageofmorethan45 million was invested in 187 projects to restore over 150 ha of oyster reef habitat, with projects most heavily concentrated in the Chesapeake Bay area and Florida Gulf coast. Trends over time indicate that projects are being implemented at larger scales, increasing from an average of less than 0.4 ha in 2000 to over 1 ha on average in 2011. Costs per unit decreased from an average of more than 2.1 million per ha in 2000 to just over $500,000 per ha in 2011. However, our analysis confirms one major problem hindering the field of restoration ecology: a lack of monitoring data or project-specific assessments of success. Habitat restoration has become an increasingly common effort in the policy sector, and gaps identified through this analysis can help inform future policy making and implementation. Better facilitation of data dissemination and further research on economies of scale in restoration projects are two key areas for improvement. As the field of restoration ecology continues to grow, it is critical that both new and current restoration practitioners, scientists, and decision-makers are able to learn from past projects and apply that collective knowledge to future restoration efforts

    Habitat assessment of a restored oyster reef in South Texas

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    Oyster reefs are important foundational habitats and provide many ecosystem services. A century of habitat degradation has resulted in substantial reductions in the extent and quality of oyster reefs in many estuaries, thus spurring restoration efforts. In this study, a 1.5 ha oyster reef complex was constructed in Copano Bay, Texas to restore habitat for oysters and associated fauna. Oysters and resident and transient fishes and crustaceans were monitored at the restored reef as well as at nearby natural oyster reef and unrestored bottom (i.e., dense mud with shell hash) habitats for two years following reef construction. The restored reef had substantial oyster recruitment and growth, with oyster abundance and size comparable to nearby habitats within the first year. Resident and transient fauna communities recruited to the restored reef within six months post-construction, and abundance and diversity were comparable to nearby habitats. Significant changes observed in oyster densities between the first and second year post-restoration demonstrate the importance of monitoring over multiple years to capture multiple recruitment cycles and growth to market size. Nekton densities did not change significantly after the first year, but changes in community assemblages were observed through the end of the study. The high densities of oysters and resident nekton relative to other studies indicate that this restoration project was successful in restoring suitable habitat. The design of the reef complex, consisting of relatively high-relief reef mounds and deeper corridors, likely contributed to the relatively high oyster and nekton densities observed in this study. Overall, the restored reef in this study showed tremendous near-term success in providing important ecological functions associated with habitat provision and oyster production

    Dataset associated with "Inspiration, inoculation, and introductions are all critical to successful mentorship for undergraduate women pursuing geoscience careers"

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    Survey data were collected via the online Qualtrics survey system one week prior and three months after a professional development workshops held in the winter (January/February) of 2019. Regional professional development workshops were held at Colorado State University (Front Range workshop) and North Carolina State University (Carolinas workshop). This repository contains the data file associated with the pre- and post-workshop surveys utilized in the analyses presented in this research article.Diversity in the geosciences is low despite efforts to improve the representation of different groups in society, for example in terms of gender. Specifically, women are underrepresented in recruitment and retention at every stage of the academic to professional pipeline. Mentoring programs can improve women's motivation and persistence in science, technology, engineering and mathematics (STEM) career pathways. However, mentorship programs consist of multiple components that vary in complexity and cost, which can limit scalability. Here we present results from a randomized experiment with 158 undergraduate women majoring in a geoscience field to identify the critical elements of a successful mentorship program. The combination of three factors was necessary to increase mentoring, motivation, and persistence: inspiration through exposure to geoscience careers via female role models, inoculation through training on how to grow their mentor network and overcome obstacles, and an introduction to a local female geoscientist mentor.National Science Foundation through grant number DUE-1431795, DUE-1431823, and DUE-1460229
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