1,304 research outputs found
Accreditation of Higher Education in the UK: The rise of PSRBs & potential influences
This poster provides a graphical illustration of data collected to identify when Professional, Statutory and Regulatory Bodies (PSRB’s) that accredit UK undergraduate degrees began their accreditation programmes. PSRB’s were identified from data held by the Higher Education Statistics Agency (HESA) and contacted individually to establish when they began accrediting, leading to the collation of a unique set of figures that can be archived. The data is shown alongside the growth of HE institutions in the same period and key events that may have impacted on their numbers
A model independent analysis of gluonic pole matrix elements and universality of TMD fragmentation functions
Gluonic pole matrix elements explain the appearance of single spin
asymmetries (SSA) in high-energy scattering processes. They involve a
combination of operators which are odd under time reversal (T-odd). Such matrix
elements appear in principle both for parton distribution functions and parton
fragmentation functions. We show that for parton fragmentation functions these
gluonic pole matrix elements vanish as a consequence of the analytic structure
of scattering amplitudes in Quantum Chromodynamics. This result is important in
the study of the universality of transverse momentum dependent (TMD)
fragmentation functions.Comment: 5 pages, 5 figures, version to appear in Phys. Rev.
Life goes on: Archaeobotanical investigations of diet and ritual at Angkor Thom, Cambodia (fourteenth to fifteenth centuries CE)
This is the first time an archaeobotanical analysis based on macroremains, both charred and desiccated, from Cambodia is reported. The archaeobotanical samples are rich and provide evidence of rice processing, consumption of non-indigenous pulses, and the use of economic crops. The evidence is supported by data from inscriptions, texts and historical ethnography. This study demonstrates that the city of Angkor in the 14th and 15th centuries CE, despite its decline, was still occupied. Angkor’s inhabitants continued their everyday lives cultivating and consuming their staple food, rice, with a suite of pulses, and also used the harvests in the performance of rituals
The Mach-Zehnder and the Teleporter
We suggest a self-testing teleportation configuration for photon q-bits based
on a Mach-Zehnder interferometer. That is, Bob can tell how well the input
state has been teleported without knowing what that input state was. One could
imagine building a "locked" teleporter based on this configuration. The
analysis is performed for continuous variable teleportation but the arrangement
could equally be applied to discrete manipulations.Comment: 4 pages, 5 figure
Proposal for the Measurement of Bell-like Correlations from Continuous Variables
We show theoretically that Bell-type correlations can be observed between
continuous variable measurements performed on a parametric source. An auxiliary
measurement, performed on the detection environment, negates the possibility of
constructing a local realistic description of these correlations
Entanglement swapping using continuous variables
We investigate the efficacy with which entanglement can be teleported using a
continuous measurement scheme. We show that by using the correct gain for the
classical channel the degree of violation of locality that can be demonstrated
(using a CH type inequality) is {\it not} a function of the level of
entanglement squeezing used in the teleportation. This is possible because a
gain condition can always be choosen such that passage through the teleporter
is equivalent to pure attenuation of the input field.Comment: 8 pages, 4 figure
Development and evaluation of rapid novel isothermal amplification assays for important veterinary pathogens: Chlamydia psittaci and Chlamydia pecorum
© 2017 Jelocnik et al. Background. Chlamydia psittaci and Chlamydia pecorum are important veterinary pathogens, with the former also being responsible for zoonoses, and the latter adversely affecting koala populations in Australia and livestock globally. The rapid detection of these organisms is still challenging, particularly at the point-of-care (POC). In the present study, we developed and evaluated rapid, sensitive and robust C. psittaci-specific and C. pecorum-specific Loop Mediated Isothermal Amplification (LAMP) assays for detection of these pathogens. Methods and Materials. The LAMP assays, performed in a Genie III real-time fluo- rometer, targeted a 263 bp region of the C. psittaci-specific Cps_0607 gene or a 209 bp region of a C. pecorum-specific conserved gene CpecG_0573, and were evaluated using a range of samples previously screened using species-specific quantitative PCRs (qPCRs). Species-specificity for C. psittaci and C. pecorum LAMP targets was tested against DNA samples from related chlamydial species and a range of other bacteria. In order to evaluate pathogen detection in clinical samples, C. psittaci LAMP was evaluated using a total of 26 DNA extracts from clinical samples from equine and avian hosts, while for C. pecorum LAMP, we tested a total of 63 DNA extracts from clinical samples from koala, sheep and cattle hosts. A subset of 36 C. pecorum samples was also tested in a thermal cycler (instead of a real-time fluorometer) using newly developed LAMP and results were determined as an end point detection. We also evaluated rapid swab processing (without DNA extraction) to assess the robustness of these assays. Results. Both LAMP assays were demonstrated to species-specific, highly reproducible and to be able to detect as little as 10 genome copy number/reaction, with a mean amplification time of 14 and 24 min for C. psittaci and C. pecorum, respectively. When testing clinical samples, the overall congruence between the newly developed LAMP assays and qPCR was 92.3% for C. psittaci (91.7% sensitivity and 92.9% specificity); and 84.1% for C. pecorum (90.6% sensitivity and 77.4% specificity). For a subset of 36 C. pecorum samples tested in a thermal cycler using newly developed LAMP, we observed 34/36 (94.4%) samples result being congruent between LAMP performed in fluorometer and in thermal cycler. Rapid swab processing method evaluated in this study also allows for chlamydial DNA detection using LAMP. Discussion. In this study, we describe the development of novel, rapid and robust C. psittaci-specific and C. pecorum-specific LAMP assays that are able to detect these bacteria in clinical samples in either the laboratory or POC settings. With further development and a focus on the preparation of these assays at the POC, it is anticipated that both tests may fill an important niche in the repertoire of ancillary diagnostic tools available to clinicians
Comparison of Boltzmann Kinetics with Quantum Dynamics for a Chiral Yukawa Model Far From Equilibrium
Boltzmann equations are often used to describe the non-equilibrium
time-evolution of many-body systems in particle physics. Prominent examples are
the computation of the baryon asymmetry of the universe and the evolution of
the quark-gluon plasma after a relativistic heavy ion collision. However,
Boltzmann equations are only a classical approximation of the quantum
thermalization process, which is described by so-called Kadanoff-Baym
equations. This raises the question how reliable Boltzmann equations are as
approximations to the complete Kadanoff-Baym equations. Therefore, we present
in this article a detailed comparison of Boltzmann and Kadanoff-Baym equations
in the framework of a chirally invariant Yukawa-type quantum field theory
including fermions and scalars. The obtained numerical results reveal
significant differences between both types of equations. Apart from
quantitative differences, on a qualitative level the late-time universality
respected by Kadanoff-Baym equations is severely restricted in the case of
Boltzmann equations. Furthermore, Kadanoff-Baym equations strongly separate the
time scales between kinetic and chemical equilibration. In contrast to this
standard Boltzmann equations cannot describe the process of quantum-chemical
equilibration, and consequently also cannot feature the above separation of
time scales.Comment: 17 pages, 8 figures, REVTeX
Comparative genomics of koala, cattle and sheep strains of Chlamydia pecorum
© 2014 Bachmann et al.; licensee BioMed Central Ltd. Background: Chlamydia pecorum is an important pathogen of domesticated livestock including sheep, cattle and pigs. This pathogen is also a key factor in the decline of the koala in Australia. We sequenced the genomes of three koala C. pecorum strains, isolated from the urogenital tracts and conjunctiva of diseased koalas. The genome of the C. pecorum VR629 (IPA) strain, isolated from a sheep with polyarthritis, was also sequenced.Results: Comparisons of the draft C. pecorum genomes against the complete genomes of livestock C. pecorum isolates revealed that these strains have a conserved gene content and order, sharing a nucleotide sequence similarity > 98%. Single nucleotide polymorphisms (SNPs) appear to be key factors in understanding the adaptive process. Two regions of the chromosome were found to be accumulating a large number of SNPs within the koala strains. These regions include the Chlamydia plasticity zone, which contains two cytotoxin genes (toxA and toxB), and a 77 kbp region that codes for putative type III effector proteins. In one koala strain (MC/MarsBar), the toxB gene was truncated by a premature stop codon but is full-length in IPTaLE and DBDeUG. Another five pseudogenes were also identified, two unique to the urogenital strains C. pecorum MC/MarsBar and C. pecorum DBDeUG, respectively, while three were unique to the koala C. pecorum conjunctival isolate IPTaLE. An examination of the distribution of these pseudogenes in C. pecorum strains from a variety of koala populations, alongside a number of sheep and cattle C. pecorum positive samples from Australian livestock, confirmed the presence of four predicted pseudogenes in koala C. pecorum clinical samples. Consistent with our genomics analyses, none of these pseudogenes were observed in the livestock C. pecorum samples examined. Interestingly, three SNPs resulting in pseudogenes identified in the IPTaLE isolate were not found in any other C. pecorum strain analysed, raising questions over the origin of these point mutations.Conclusions: The genomic data revealed that variation between C. pecorum strains were mainly due to the accumulation of SNPs, some of which cause gene inactivation. The identification of these genetic differences will provide the basis for further studies to understand the biology and evolution of this important animal pathogen
The construction of identities in narratives about serious leisure occupations
Engagement in occupation contributes to the shaping of identity throughout the human life. The act of telling about such engagement involves interaction based on symbolic meaning; the speaker constructing an identity by conveying how the occupation is personally meaningful. This study explored meaning in narratives told by people who engage in serious leisure occupations. A total of 78 narratives were extracted from interviews with 17 people who invest considerable time and other resources into their leisure. Analysis focused on the content, structure and performance of each narrative in order to explore meaning. The meanings were organised into a framework based around three dimensions: the located self, the active self and the changing self. Each dimension has facets that the individual might emphasise, constructing a unique identity. The framework offers a structured basis for conceptualising how occupation contributes to the shaping of the internalised self and the socially situated identity
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