Resisting Neoliberal Policy and the Intensification of Racial Capitalism Through Fostering Critical Awareness: A Series of Educational Workshops to Occur within Social Justice Unions

This is a master’s thesis that focuses on neoliberal policy within the education system. In this thesis I prove that neoliberal policy intensifies the current overarching framework of racial capitalism. I explore central elements of neoliberalism and racial capitalism to bridge understanding of how the two are intertwined with the goal of providing the reader an understanding of how neoliberal policy is detrimental. After an introduction to my thematic concern, an in-depth analysis of theoretical frameworks that helped shaped my understanding of my concern, and a historical and literature review focused on central elements of my concerns, I propose of program that seeks to bring social justice teachers unions and community members together to engage in critical pedagogy that leads to a critical awareness. It is my hope that this critical awareness will drive collective resistance and organizing to offer a genuine alternative to the intensification of racial capitalism, leading to social transformation away from class divisions

Design Issues and in Field Tests of the New Sustainable Tractor LOCOSTRA

first, in Italy, focusing on the agricultural application of the machine, in natural scenarios with different ground and vegetatio

Cell Transplant

Human induced pluripotent stem cells (hiPSCs) are a most appealing source for cell replacement therapy in acute brain lesions. We evaluated the potential of hiPSC therapy in stroke by transplanting hiPSC-derived neural progenitor cells (NPCs) into the postischemic striatum. Grafts received host tyrosine hydroxylase-positive afferents and contained developing interneurons and homotopic GABAergic medium spiny neurons that, with time, sent axons to the host substantia nigra. Grafting reversed stroke-induced somatosensory and motor deficits. Grafting also protected the host substantia nigra from the atrophy that follows disruption of reciprocal striatonigral connections. Graft innervation by tyrosine hydoxylase fibers, substantia nigra protection, and somatosensory functional recovery were early events, temporally dissociated from the slow maturation of GABAergic neurons in the grafts and innervation of substantia nigra. This suggests that grafted hiPSC-NPCs initially exert trophic effects on host brain structures, which precede integration and potential pathway reconstruction. We believe that transplantation of NPCs derived from hiPSCs can provide useful interventions to limit the functional consequences of stroke through both neuroprotective effects and reconstruction of impaired pathways

An overview of tissue engineering approaches for management of spinal cord injuries

Severe spinal cord injury (SCI) leads to devastating neurological deficits and disabilities, which necessitates spending a great deal of health budget for psychological and healthcare problems of these patients and their relatives. This justifies the cost of research into the new modalities for treatment of spinal cord injuries, even in developing countries. Apart from surgical management and nerve grafting, several other approaches have been adopted for management of this condition including pharmacologic and gene therapy, cell therapy, and use of different cell-free or cell-seeded bioscaffolds. In current paper, the recent developments for therapeutic delivery of stem and non-stem cells to the site of injury, and application of cell-free and cell-seeded natural and synthetic scaffolds have been reviewed

Plasticité post-lésionnelle des réseaux neurovégétatifs centraux : cas du réseau respiratoire. Récupération fonctionnelle après lésion médullaire et transplantation de cellules gliales gainantes olfactives

Ce travail doctoral a étudié, après hémisection cervicale chez le rat adulte, l'incidence de la stratégie de transplantation post-traumatique de cellules gliales olfactives sur la plasticité post-lésionnelle d'un réseau neurovégétatif central (réseau respiratoire) et sur la récupération fonctionnelle qui en résulte. Trois à 6 mois post-lésionnels, une récupération fonctionnelle conséquente des activités phrénique et diaphragmatique ipsilatérales à la lésion (80% et 73% de l'activité controlatérale ; Animaux Témoins : 29% et 10%) est obtenue chez les animaux Transplantés. 57% de l'activité phrénique relevée chez ces animaux persiste après élimination de toute incidence d'origine controlatérale. Aucune activité ipsilatérale semblable n'a pu être mise en évidence chez les Témoins. L'obtention de réponses phréniques post-synaptiques ipsilatérales à des stimulations sus-lésionnelle, chez les transplantés uniquement, révèle la présence d'une réinnervation phrénique imputable à la stratégie.AIX-MARSEILLE3-BU Sc.St Jérô (130552102) / SudocSudocFranceF

Grafts of Olfactory Stem Cells Restore Breathing and Motor Functions after Rat Spinal Cord Injury

International audienceStem cells are considered as promising tools to repair diverse tissue injuries. Among the different stem cell types, the “olfactory ectomesenchymal stem cells” (OE-MSCs) located in the adult olfactory mucosa stand as one of the best candidates. Here, we evaluated if OE-MSC grafts could decrease memory impairments due to ischemic injury. OE-MSCs were collected from syngeneic F344 rats. After a two-step global cerebral ischemia, inducing hippocampal lesions, learning abilities were evaluated using an olfactory associative discrimination task. Cells were grafted into the hippocampus 5 weeks after injury and animal’s learning abilities reassessed. Rats were then sacrificed and the brains collected for immunohistochemical analyses. We observed significant impairments in learning and memory abilities following ischemia. However, 4 weeks after OE-MSC grafts, animals displayed learning and memory performances similar to those of controls, while sham rats did not improve them. Immunohistochemical analyses revealed that grafts promoted neuroblast and glial cell proliferation, which could permit to restore cognitive functions. These results demonstrated, for the first time, that syngeneic transplantations of OE-MSCs in rats can restore cognitive abilities impaired after brain injuries and provide support for the development of clinical studies based on grafts of OE-MSCs in amnesic patients following brain injuries

A simple Procedure for Designing Blast Resistant Wheels

In this paper, a simple procedure to design a blast resistant wheel is presented. Finite element analysis is employed to provide preliminary evaluations on the blast resistance of the wheel; the issues of such work are analyzed and the results are shown in order to prove the validity of the proposed procedure. The analysis is carried out in order to avoid unnecessary experimental tests, without requiring a high computational burden. The method and the setup used can he adopted to design any blast resistant mechanical component intended to work under the same conditions. (C) 2013 The Authors. Published by Elsevier Ltd. Selection and peer-review under responsibility of the organizing and review committee of IConDM 2013