243 research outputs found
Navigation input to level C OFT navigation functional subsystem software requirements (rendezvous onorbit-2)
Navigation software design requirements are presented for the orbital flight test phase of space shuttle. Computer loads for the entire onorbit-2 operation are documented
How an antenna launches its input power into radiation: the pattern of the Poynting vector at and near an antenna
In this paper I first address the question of whether the seat of the power
radiated by an antenna made of conducting members is distributed over the
``arms'' of the antenna according to -J . E, where J is the specified current
density and E is the electric field produced by that source. Poynting's theorem
permits only a global identification of the total input power, usually from a
localized generator, with the total power radiated to infinity, not a local
correspondence of -J . E dv with some specific radiated power, r^2 S . n dO. I
then describe a model antenna consisting of two perfectly conducting
hemispheres of radius a separated by a small equatorial gap across which occurs
the driving oscillatory electric field. The fields and surface current are
determined by solution of the boundary value problem. In contrast to the first
approach (not a boundary value problem), the tangential electric field vanishes
on the metallic surface. There is no radial Poynting vector normal to the
surface. Numerical examples are shown to illustrate how the energy flows from
the input region of the gap and is guided near the antenna by its ``arms''
until it is launched at larger r/a into the radiation pattern determined by the
value of ka.Comment: 24pages, 8 figures, submitted for publicatio
Perturbed Defects and T-Systems in Conformal Field Theory
Defect lines in conformal field theory can be perturbed by chiral defect
fields. If the unperturbed defects satisfy su(2)-type fusion rules, the
operators associated to the perturbed defects are shown to obey functional
relations known from the study of integrable models as T-systems. The procedure
is illustrated for Virasoro minimal models and for Liouville theory.Comment: 24 pages, 13 figures; v2: typos corrected, in particular in (2.10)
and app. A.2, version to appear in J.Phys.
Quantum Calogero-Moser Models: Integrability for all Root Systems
The issues related to the integrability of quantum Calogero-Moser models
based on any root systems are addressed. For the models with degenerate
potentials, i.e. the rational with/without the harmonic confining force, the
hyperbolic and the trigonometric, we demonstrate the following for all the root
systems: (i) Construction of a complete set of quantum conserved quantities in
terms of a total sum of the Lax matrix (L), i.e. (\sum_{\mu,\nu\in{\cal
R}}(L^n)_{\mu\nu}), in which ({\cal R}) is a representation space of the
Coxeter group. (ii) Proof of Liouville integrability. (iii) Triangularity of
the quantum Hamiltonian and the entire discrete spectrum. Generalised Jack
polynomials are defined for all root systems as unique eigenfunctions of the
Hamiltonian. (iv) Equivalence of the Lax operator and the Dunkl operator. (v)
Algebraic construction of all excited states in terms of creation operators.
These are mainly generalisations of the results known for the models based on
the (A) series, i.e. (su(N)) type, root systems.Comment: 45 pages, LaTeX2e, no figure
Dynamic expression of genes associated with schizophrenia and bipolar disorder across development
Common genetic variation contributes a substantial proportion of risk for both schizophrenia and bipolar disorder. Furthermore, there is evidence of significant, but not complete, overlap in genetic risk between the two disorders. It has been hypothesised that genetic variants conferring risk for these disorders do so by influencing brain development, leading to the later emergence of symptoms. The comparative profile of risk gene expression for schizophrenia and bipolar disorder across development over different brain regions however remains unclear. Using genotypes derived from genome-wide associations studies of the largest available cohorts of patients and control subjects, we investigated whether genes enriched for schizophrenia and bipolar disorder association show a bias for expression across any of 13 developmental stages in prefrontal cortical and subcortical brain regions. We show that genetic association with schizophrenia is positively correlated with expression in the prefrontal cortex during early midfetal development and early infancy, and negatively correlated with expression during late childhood, which stabilises in adolescence. In contrast, risk-associated genes for bipolar disorder did not exhibit a bias towards expression at any prenatal stage, although the pattern of postnatal expression was similar to that of schizophrenia. These results highlight the dynamic expression of genes harbouring risk for schizophrenia and bipolar disorder across prefrontal cortex development and support the hypothesis that prenatal neurodevelopmental events are more strongly associated with schizophrenia than bipolar disorder
The research-teaching nexus: A case study of students' awareness, experiences and perceptions of research
This paper presents a case study of students' awareness, experiences and perceptions of research in a 'new' university in the UK. The findings are based on a questionnaire of almost 200 students and five small group interviews. Many of the students participating in this research perceived clear benefits to their learning from staff research, including being taught by enthusiastic staff, enhanced staff credibility, and the reflected glory of being taught by well-known researchers. However, they also perceived disadvantages, particularly with regard to staff availability, and did not believe that staff research should take priority over their needs as learners. They recognised that their awareness of the nature of research and the development of research skills increased most when they were actively involved in undertaking research projects. Several students also perceived benefits for future employment from their participation in research activities. The questionnaire has been used by several other universities around the world to benchmark their practices. © 2010 Taylor & Francis
A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia
chizophrenia is a complex highly heritable disorder. Genome-wide association studies (GWAS) have identified multiple loci that influence the risk of developing schizophrenia, although the causal variants driving these associations and their impacts on specific genes are largely unknown. We identify a significant correlation between schizophrenia risk and expression at 89 genes in dorsolateral prefrontal cortex (P †9.43x10â6), including 20 novel genes. Genes whose expression correlate with schizophrenia were enriched for those involved in abnormal CNS synaptic transmission (PFDR = 0.02) and antigen processing and presentation of peptide antigen via MHC class I (PFDR = 0.02). Within the CNS synaptic transmission set, we identify individual significant candidate genes to which we assign direction of expression changes in schizophrenia. The findings provide strong candidates for experimentally probing the molecular basis of synaptic pathology in schizophrenia
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