Viewpoint: filovirus haemorrhagic fever outbreaks: much ado about nothing?

The recent outbreak of Marburg haemorrhagic fever in the Democratic Republic of Congo has put the filovirus threat back on the international health agenda. This paper gives an overview of Marburg and Ebola outbreaks so far observed and puts them in a public health perspective. Damage on the local level has been devastating at times, but was marginal on the international level despite the considerable media attention these outbreaks received. The potential hazard of outbreaks, however, after export of filovirus from its natural environment into metropolitan areas, is argued to be considerable. Some avenues for future research and intervention are explored. Beyond the obvious need to find the reservoir and study the natural history, public health strategies for a more timely and efficient response are urgently needed

Organisation of Health Care During an Outbreak of Marburg Haemorrhagic Fever in the Democratic Republic of Congo, 1999.

Organising health care was one of the tasks of the International Scientific and Technical Committee during the 1998-1999 outbreak in Durba/Watsa, in the north-eastern province (Province Orientale), Democratic Republic of Congo. With the logistical support of Médecins sans Frontières (MSF), two isolation units were created: one at the Durba Reference Health Centre and the other at the Okimo Hospital in Watsa. Between May 6th, the day the isolation unit was installed and May 19th, 15 patients were admitted to the Durba Health Centre. In only four of them were the diagnosis of Marburg haemorrhagic fever (MHF) confirmed by laboratory examination. Protective equipment was distributed to health care workers and family members caring for patients. Information about MHF, modes of transmission and the use of barrier nursing techniques was provided to health care workers and sterilisation procedures were reviewed. In contrast to Ebola outbreaks, there was little panic among health care workers and the general public in Durba and all health services remained operational

Effect of alumina and titanium nitrides inclusions on mechanical properties in high alloyed steels

peer reviewedevery commercial steel product in varying amounts. Since inclusions significantly influence properties and behaviour of materials and at the same time give indications on the quality of the steel, it is quite interesting to precise their nature and their origin. In this paper concerning a project involved in the COST 517 framework, studied alloys are high alloy steels. The raw materials were obtained from the conventionally electrical cast ingot and the Electro Slag Refining processes. The purpose is to compare various inclusions produced by these different processes and their effect on the mechanical properties. The raw material because of the melting processes themselves, leads to a product with a good to a great cleanliness, and tiny inclusions, which are haphazardly distributed. The actual ASTM E45 chart seems to be inappropriate, as the inclusions founded are too small in size. Therefore, we manage to develop a specific procedure for the study of such inclusions. The different types of inclusions encountered are oxides, titanium nitrides, and manganese sulphides. Studying the effect on mechanical properties, oxides often seem to initiate fatigue fracture

Design optimization and performance capabilities of the fast neutron imaging telescope (FNIT)

We describe the design optimization process and performance characterization of a next generation neutron telescope, with imaging and energy measurement capabilities, sensitive to neutrons in the 1-20 MeV energy range. The response of the Fast Neutron Imaging Telescope (FNIT), its efficiency in neutron detection, energy resolution and imaging capabilities were characterized through a combination of lab tests and Monte Carlo simulations. Monte Carlo simulations, together with experimental data, are also being used in the development and testing of the image reconstruction algorithm. FNIT was initially conceived to study solar neutrons as a candidate instrument for the Inner Heliosphere Sentinel (IHS) spacecraft. However, the design of this detector was eventually adapted to locate Special Nuclear Material (SNM) sources for homeland security purposes, by detecting fission neutrons. In either case, the detection principle is based on multiple elastic neutron-proton scatterings in organic scintillator. By reconstructing event locations and measuring the recoil proton energies, the direction and energy spectrum of the primary neutron flux can be determined and neutron sources identified. This paper presents the most recent results arising from our efforts and outlines the performance of the FNIT detector

A systematic review of the socio-economic impacts of large-scale tree plantations, worldwide

Corrigendum: The author regrets to inform readers about an error in the legend of Fig. 8. Currently the legend reads "Fig. 8. Associations between cate-gories." However, the correct version is "Fig. 8. Associations betweencategories. Yellow lines refer to both mutually-reinforcing and negatingassociations. Linewidth reflects the relative abundance of such asso-ciations in the evidence base."The author apologizes for this error and any consequent incon-venience to readers. (Global Environmental Change Volume 57, July 2019, 101931)Since their widespread introduction in the 1980s, large-scale tree plantations have seen contestations over their socio-economic impacts. With the establishment of new plantations on the rise, a review of the literature examining their impacts on local communities is needed to inform policies and practices. In this systematic review, we followed an a priori protocol to reduce the selection biases inherent to conventional literature reviews, and considered both grey and peer-reviewed literature. Of the 20,450 studies identified in our literature search, only 92 studies met our predefined inclusion criteria. However, only 22 studies presented a clear comparator and considered confounding factors in their analysis. Of the 251 impacts identified in this sample, most impacts across the nine categories were characterised as predominantly negative impacts attributed to large-scale tree plantations. Impacts on employment (22% of reported impacts/of which 41% predominantly negative), land (21%/81%), livelihoods (12%/48%) and the often intertwined social impacts (20%/69%) were the most commonly considered categories, within which a majority of studies agreed on the impact dynamics when in similar contexts, resembling the dynamics observed in other large-scale land-based investments. Most impacts were reported from Southeast Asia (34% of reported impacts), South America (29%), Africa (23%) and Australasia (12%). We corroborate that costs of large-scale tree plantations for residents tend to be front-loaded, especially when plantations have displaced customary land uses, and possible benefits to accrue over time, moderated by the emergence of local processing and complementary livelihood activities. However, given the methodological inconsistencies in our sample and the under-representation of areas known to have undergone plantation development, strong global evidence on the long-term socio-economic impacts of large-scale tree plantations remains limited.Peer reviewe

On-sky results of the adaptive optics MACAO for the new IR-spectrograph CRIRES at VLT

The adaptive optics MACAO has been implemented in 6 focii of the VLT observatory, in three different flavors. We present in this paper the results obtained during the commissioning of the last of these units, MACAO-CRIRES. CRIRES is a high-resolution spectrograph, which efficiency will be improved by a factor two at least for point-sources observations with a NGS brighter than R=15. During the commissioning, Strehl exceeding 60% have been observed with fair seeing conditions, and a general description of the performance of this curvature adaptive optics system is done.Comment: SPIE conference 2006, Advances in adaptive optics, 12 pages, 11 figure