126 research outputs found
Generation of high-field terahertz pulses in an HMQ-TMS organic crystal pumped by an ytterbium laser at 1030 nm
Copyright information see: https://www.osapublishing.org/submit/review/copyright_permissions.cfm#oalWe present the generation of high-peak-electric-field terahertz pulses via collinear optical rectification in a 2-(4-hydroxy-3-methoxystyryl)-1-methilquinolinium-2,4,6-trimethylbenzenesulfonate (HMQ-TMS) organic crystal. The crystal is pumped by an amplified ytterbium laser system, emitting 170-fs-long pulses centered at 1030 nm. A terahertz peak electric field greater than 200 kV/cm is obtained for 420 ”J of optical pump energy, with an energy conversion efficiency of 0.26% - about two orders of magnitude higher than in common inorganic crystals collinearly pumped by amplified femtosecond lasers. An open-aperture Z-scan measurement performed on an n-doped InGaAs thin film using such terahertz source shows a nonlinear increase in the terahertz transmission of about 2.2 times. Our findings demonstrate the potential of this terahertz generation scheme, based on ytterbium laser technology, as a simple and efficient alternative to the existing intense table-top terahertz sources. In particular, we show that it can be readily used to explore nonlinear effects at terahertz frequencies
Abdominal Aortic Aneurysm Repair in Patient with a Renal Allograft: A Case Report
Renal transplant recipients requiring aortic reconstruction due to abdominal aortic aneurysm (AAA) pose a unique clinical problem. The concern during surgery is causing ischemic injury to the renal allograft. A variety of strategies for protection of the renal allograft during AAA intervention have been described including a temporary shunt, cold renal perfusion, extracorporeal bypass, general hypothermia, and endovascular stent-grafting. In addition, some investigators have reported no remarkable complications of the renal allograft without any specific measures. We treated a case of AAA in a patient with a renal allograft using a temporary aortofemoral shunt with good result. Since this technique is safe and effective, it should be considered in similar patients with AAA and previously placed renal allografts
Optimal target blood pressure for the primary prevention of hemorrhagic stroke: a nationwide observational study
BackgroundThere are few reports on the preventative value of intensive blood pressure (BP) management for stroke, especially hemorrhagic stroke (HS), after new criteria for hypertension (HTN) were announced by the American College of Cardiology/American Heart Association in 2017.AimsThis study aimed to identify the optimal BP for the primary prevention of HS in a healthy population aged between 20 and 65 years.MethodsWe conducted a 10-year observational study on the risk of HS, subclassified as intracerebral hemorrhage (ICH) and subarachnoid hemorrhage (SAH) according to BP categories (e.g., low normal BP, high normal BP, elevated BP, stage 1 HTN, and stage 2 HTN) using the National Health Insurance Service Database.ResultsOut of 8,327,751 participants who underwent a health checkup in 2008, 949,550 were included in this study and observed from 2009 to 2018. The risk of ICH was significantly increased in men with stage 2 HTN {adjusted hazard ratio [aHR] 2.002 [95% confidence interval (CI) 1.203â3.332]} and in women with stage 1 HTN [aHR 2.021 (95% CI, 1.251â3.263)]. The risk of SAH was significantly increased in both men [aHR 1.637 (95% CI, 1.066â2.514)] and women [aHR 4.217 (95% CI, 2.648â6.715)] with stage 1 HTN. Additionally, the risk of HS was significantly increased in men with stage 2 HTN [aHR 3.034 (95% CI, 2.161â4.260)] and in women with stage 1 HTN [aHR 2.976 (95% CI, 2.222â3.986)].ConclusionTo prevent primary HS, including ICH and SAH, BP management is recommended for adults under the age of 65 years with stage 1 HTN
Design strategy of highly efficient nonlinear optical orangeâcolored crystals with two electronâwithdrawing groups
A new class of highly efficient nonlinear optical organic salt crystals is reported. In nonlinear optics based on organic materials, it is well known that using two electron-withdrawing groups (EWGs) onto cationic electron acceptors instead of conventional one EWG remarkably enhances microscopic optical nonlinearity for chromophores. However, the corresponding organic crystals possessing enhanced large macroscopic optical nonlinearity have not been reported yet. Herein, a design strategy is proposed for obtaining highly efficient nonlinear optical crystals based on two EWGs in cationic electron acceptors. Introducing a phenolic electron donor, promoting a head-to-tail interionic assembly, along with a two-EWG N-pyrimidinyl pyridinium electron acceptor in cationic chromophores results in a preferred non-centrosymmetric, perfectly parallel alignment of chromophores in crystal. Newly designed OPR (4-(4-hydroxystyryl)-1-(pyrimidin-2-yl)pyridinium) crystals exhibit approximately two times larger effective first hyperpolarizability than that of analogous N-alkyl OHP (4-(4-hydroxystyryl)-1-methylpyridinium) crystals based on only one EWG. OPR crystals exhibit comparable second-order optical nonlinearity to benchmark red-colored DAST (4-(4-(dimethylamino)styryl)-1-methylpyridinium 4-methylbenzenesulfonate) crystals, but a significant blue-shifted absorption resulting in orange-color crystals. Therefore, phenolic organic salt crystals using two EWGs are highly promising materials for various nonlinear optical applications
Highâdensity organic electroâoptic crystals for ultraâbroadband THz spectroscopy
Ultra-broadband THz photonics covering the 0.3â20 THz range provides a very attractive foundation for a wide range of basic research and industrial applications. However, the lack of ultra-broadband THz devices has yet to be overcome. In this work, high-density organic electro-optic crystals are newly developed for efficient THz wave generation in a very broad THz spectral range and are successfully used for a broadband THz time-domain spectroscopy. The new organic THz generator crystals, namely the OHP-TFS crystals, have very low void volume, high density, and are shown to cover the ultra-broadband THz spectrum up to about 15 THz, which cannot be easily accessed with the more widely used inorganic-based THz generators. In addition to the very favorable broadband properties, the generated THz electric-field amplitude at the pump wavelength of 1560 nm is about 40 times higher than that generated by a commercial inorganic THz generator (ZnTe crystal). By using the newly developed OHP-TFS as generation crystal in a compact table-top all-organic THz time-domain spectrometer based on a low-cost telecom fiber laser, the optical characteristics of a model material are successfully determined in the broad 1.5â12.5 THz range with high accuracy
MHz-repetition-rate, sub-mW, multi-octave THz wave generation in HMQ-TMS
We demonstrate the first megahertz (MHz) repetition-rate, broadband terahertz (THz) source based on optical rectification in the organic crystal HMQ-TMS driven by a femtosecond Yb:fibre laser. Pumping at 1035 nm with 30 fs pulses, we achieve few-cycle THz emission with a smooth multi-octave spectrum that extends up to 6 THz at -30 dB, with conversion efficiencies reaching 10-4 and an average output power of up to 0.38 mW. We assess the thermal damage limit of the crystal and conclude a maximum fluence of âŒ1.8 mJ·cm-2 at 10 MHz with a 1/e2 pump beam diameter of 0.10 mm. We compare the performance of HMQ-TMS with the prototypical inorganic crystal gallium phosphide (GaP), yielding a tenfold electric field increase with a peak on-axis field strength of 7 kV·cm-1 and almost double the THz bandwidth. Our results further demonstrate the suitability of organic crystals in combination with fibre lasers for repetition-rate scaling of broadband, high-power THz sources for time-domain spectroscopic applications
Spontaneous Sinus Conversion of Permanent Atrial Fibrillation During Treatment of Hyperkalemia
Hyperkalemia is a common adverse effect of treatment for heart failure and is associated with high mortality and morbidity. The cardiac manifestations of hyperkalemia include various electrocardiogram changes. We describe a case of a 74-year-old woman with heart failure and permanent atrial fibrillation who reverted to normal sinus rhythm during recovery from hyperkalemia
Organic broadband THz generators optimized for efficient nearâinfrared optical pumping
New organic THz generators are designed herein by molecular engineering of the refractive index, phonon mode, and spatial asymmetry. These benzothiazolium crystals simultaneously satisfy the crucial requirements for efficient THz wave generation, including having nonlinear optical chromophores with parallel alignment that provide large optical nonlinearity; good phase matching for enhancing the THz generation efficiency in the near-infrared region; strong intermolecular interactions that provide restraining THz self-absorption; high solubility that promotes good crystal growth ability; and a plate-like crystal morphology with excellent optical quality. Consequently, the as-grown benzothiazolium crystals exhibit excellent characteristics for THz wave generation, particularly at near-infrared pump wavelengths around 1100Â nm, which is very promising given the availability of femtosecond laser sources at this wavelength, where current conventional THz generators deliver relatively low optical-to-THz conversion efficiencies. Compared to a 1.0-mm-thick ZnTe crystal as an inorganic benchmark, the 0.28-mm-thick benzothiazolium crystal yields a 19 times higher peak-to-peak THz electric field with a broader spectral bandwidth (>6.5 THz) when pumped at 1140 nm. The present work provides a valuable approach toward realizing organic crystals that can be pumped by near-infrared sources for efficient THz wave generation
Round-robin test on thermal conductivity measurement of ZnO nanofluids and comparison of experimental results with theoretical bounds
Ethylene glycol (EG)-based zinc oxide (ZnO) nanofluids containing no surfactant have been manufactured by one-step pulsed wire evaporation (PWE) method. Round-robin tests on thermal conductivity measurements of three samples of EG-based ZnO nanofluids have been conducted by five participating labs, four using accurate measurement apparatuses developed in house and one using a commercial device. The results have been compared with several theoretical bounds on the effective thermal conductivity of heterogeneous systems. This study convincingly demonstrates that the large enhancements in the thermal conductivities of EG-based ZnO nanofluids tested are beyond the lower and upper bounds calculated using the models of the Maxwell and Nan et al. with and without the interfacial thermal resistance
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