How do oral NSAIDs compare to other oral analgesics right after an acute musculoskeletal injury?

Q: How do oral NSAIDs compare to other oral analgesics right after an acute musculoskeletal injury? A: nonsteroidal anti-inflammatory drugs(NSAIDs) are at least as effective as other oral analgesics (opioids, acetaminophen) in relieving pain in the first few days after an acute musculoskeletal injury. Evidence also indicates that using NSAIDs results in fewer adverse events than using narcotics (strength of recommendation [SOR]: A, systematic review of randomized controlled trials [RCTs], as well as individual RCTs).Authors: Corey Lyon, DO; Susan Piggott, MD, MPH; Shannon Langner, MD University of Colorado Family Medicine Residency, Denver; Kristen DeSanto, MSLS, MS, RD University of Colorado Health Sciences Library, Denver

Development, Implementation, and Evaluation of an Athlete-Informed Mental Skills Training Program for Elite Youth Tennis Players

Informed by athletes’ psychological needs, the current qualitative study developed, implemented, and evaluated a 15-month mental skills training (MST) program for elite youth athletes. The MST was divided into three phases that included a nine-month pre-intervention, a two-month intervention, and a four-month evaluation phase. The intervention consisted of three interactive workshops which were delivered to 11 competitive British youth tennis players (aged 8 to 15 years) and their coach (age =34). The intervention was informed by data that was collected throughout a nine-month pre-intervention phase including longitudinal observations, field notes, and semi-structured interviews. The intervention was evaluated over a four-month period through observations, field notes, athlete-workshop data, and a semi-structured interview with the coach. Results reinforced the value of the longitudinal pre-intervention phase by highlighting that the establishment of rapport between the researcher and athletes enhanced the meaningfulness and content of the MST program. Additionally, an increase in athletes’ use and regulation of PSCs was identified as a result of athletes’ improved understanding of psychological skills (i.e., self-talk, imagery, performance routines) and characteristics (i.e., focus, emotional control) (PSCs). Finally, the MST program fostered a shared subject specific language between athletes and their coach, enhancing the openness and frequency with which PSCs were talked about. Practical guidelines for future sport psychology interventions with youth athletes and their coaches are provided

Categorizing and Defining Popular Psychological Terms Used Within the Youth Athlete Talent Development Literature: A Systematic Review

Inconsistencies in the use and definition of psychological terms within the talent development literature have been identified. To advance the scientific field, the creation of a shared language is recommended. This review aimed to systematically (i) identify terms used in empirical studies to describe psychological components purported to facilitate athletes' development; (ii) analyse definition and meanings of these terms; and (iii) group, label and define terms into meaning clusters. A systematic review using a narrative approach to synthesise information was conducted. A comprehensive literature search of SPORTDiscus, PsycINFO, PsycARTICLES, and ERIC was completed in May 2015. In total 21 empirical studies, published between 2002 and 2015, met the inclusion criteria and were included in the narrative synthesis. Thematic analysis was used to analyse the findings. Identified psychological terms were categorised as psychological skills or psychological characteristics. Psychological skills were defined as athletes’ ability to use learned psychological strategies (e.g., self-talk) to regulate and facilitate the enhancement of psychological characteristics. Psychological characteristics were defined as predispositions that impact upon athlete development (e.g., self-confidence). Despite being relatively enduring and consistent across a range of situations, psychological characteristics can be regulated and enhanced through the use of psychological skills

Particular thanks and obligations’: The communications made by women to the society of antiquaries between 1776 and 1837, and their significance

This paper brings together the evidence bearing on the relationship between the Society of Antiquaries and the women who contributed to it during a significant period when archaeology, through the work of such men as Samuel Lysons and Richard Colt Hoare, was beginning to emerge as a distinct field with its own conceptual and technical systems. It takes its departure from the first substantial appearance by a woman in the Society's publications in 1776, and continues until the accession of a female monarch, Victoria, in 1837, a period of just over sixty years. It explores what women did and what reception they received and assesses the significance of this within the wider processes of the development of an understanding of the past and the shaping of gender relationships through the medium of material culture, in a period that saw fundamental changes in many areas of intellectual and social life, including levels of material consumption and the sentiments surrounding consumerism

The nature of mathematical enrichment: a case study of implementation

This paper reports a framework for describing the nature of mathematics enrichment that emerged from a case study based on the work of the NRICH Project (www.nrich.maths.org) team when producing “mathematics enrichment trails” (an ordered set of related mathematics problems and support materials). A range of data sources, including the trails, trail development sessions, related literature and the views of colleagues were used to inform the findings. The data were analysed using NVivo and involved the development of two complementary coding systems. One, drawn from the data itself, gave evidence of views of the content aspects of mathematical enrichment. The other, specifically designed and informed by the literature, was used to aid the analysis of the roles of teaching and learning inherent in views of enrichment described by participants. The framework describes the content of an enrichment curriculum as well as implications for teaching and learning, the experiences of learners and the features of settings where this occurs. To support this, some detail is provided on the role, nature and purpose of problem-solving and what constitutes a good problem. While emerging from a particular context, the framework highlights the need for debate concerning the audience for mathematics enrichment, particularly in questioning the commonly held belief that its value is in supporting the needs of the mathematically most able. The framework also has potential value through offering a focus for debate within the wider community concerning the nature of mathematics enrichment and as a reference point for evaluating the potential of existing or new curriculum to deliver mathematics enrichment

An investigation into the nature of mathematical enrichment : A case study of implementation

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors.

Proliferating cells, typically considered nonexcitable, nevertheless, exhibit regulation by bioelectric signals. Notably, voltage-gated sodium channels (VGSC) that are crucial for neuronal excitability are also found in progenitors and up-regulated in cancer. Here, we identify a role for VGSC in proliferation of Drosophila neuroblast (NB) lineages within the central nervous system. Loss of paralytic (para), the sole gene that encodes Drosophila VGSC, reduces neuroblast progeny cell number. The type II neuroblast lineages, featuring a population of transit-amplifying intermediate neural progenitors (INP) similar to that found in the developing human cortex, are particularly sensitive to para manipulation. Following a series of asymmetric divisions, INPs normally exit the cell cycle through a final symmetric division. Our data suggests that loss of Para induces apoptosis in this population, whereas overexpression leads to an increase in INPs and overall neuroblast progeny cell numbers. These effects are cell autonomous and depend on Para channel activity. Reduction of Para expression not only affects normal NB development, but also strongly suppresses brain tumor mass, implicating a role for Para in cancer progression. To our knowledge, our studies are the first to identify a role for VGSC in neural progenitor proliferation. Elucidating the contribution of VGSC in proliferation will advance our understanding of bioelectric signaling within development and disease states

Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors.

Proliferating cells, typically considered "nonexcitable," nevertheless, exhibit regulation by bioelectric signals. Notably, voltage-gated sodium channels (VGSC) that are crucial for neuronal excitability are also found in progenitors and up-regulated in cancer. Here, we identify a role for VGSC in proliferation of Drosophila neuroblast (NB) lineages within the central nervous system. Loss of paralytic (para), the sole gene that encodes Drosophila VGSC, reduces neuroblast progeny cell number. The type II neuroblast lineages, featuring a population of transit-amplifying intermediate neural progenitors (INP) similar to that found in the developing human cortex, are particularly sensitive to para manipulation. Following a series of asymmetric divisions, INPs normally exit the cell cycle through a final symmetric division. Our data suggests that loss of Para induces apoptosis in this population, whereas overexpression leads to an increase in INPs and overall neuroblast progeny cell numbers. These effects are cell autonomous and depend on Para channel activity. Reduction of Para expression not only affects normal NB development, but also strongly suppresses brain tumor mass, implicating a role for Para in cancer progression. To our knowledge, our studies are the first to identify a role for VGSC in neural progenitor proliferation. Elucidating the contribution of VGSC in proliferation will advance our understanding of bioelectric signaling within development and disease states