Q: How do oral NSAIDs compare to other oral analgesics right after an acute musculoskeletal injury? A: nonsteroidal anti-inflammatory drugs(NSAIDs) are at least as effective as other oral analgesics (opioids, acetaminophen) in relieving pain in the first few days after an acute musculoskeletal injury. Evidence also indicates that using NSAIDs results in fewer adverse events than using narcotics (strength of recommendation [SOR]: A, systematic review of randomized controlled trials [RCTs], as well as individual RCTs).Authors: Corey Lyon, DO; Susan Piggott, MD, MPH; Shannon Langner, MD University of Colorado Family Medicine Residency, Denver; Kristen DeSanto, MSLS, MS, RD University of Colorado Health Sciences Library, Denver
