Correlation among performance, hormonal and some biochemical indices in nine lines of prestice pig

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A critique of quantitative easing by the Federal Reserve System and the European Central Bank

The application of quantitative easing tools by certain central banks has been and continues to be the subject of professional debate. Therefore, this paper aims to assess an alternative scenario to the use of quantitative easing. We have used counterfactual analysis to estimate GDP growth in the US and in the Eurozone for the period during which quantitative easing was implemented, i.e., since 2009 in the US and since 2015 in the Eurozone. We used a vector autoregression (VAR) model for the analysis. We concluded that, in retrospect, the use of quantitative easing appears to be unwarranted. While there was slightly higher GDP growth in the Eurozone than there would have been without quantitative easing, there was no smoothing of the economic cycle. At the same time, returning to the inflation target took a relatively long time. In the US, quantitative easing prevented an initial slide into a deep recession and smoothed the economic cycle over the medium term. Overall, however, quantitative easing has mostly had a negative effect. One major negative is that when this instrument is used over a long time period, economic subjects gradually come to see it as a standard tool. Furthermore, inflation, central banks’ main objective, did not rise rapidly over the period in question; on the contrary, over the long term, quantitative easing has become one of the factors behind today’s higher inflation rates. An excessive monetary supply has created imbalances in the financial markets and has been a factor in price bubbles in the stock, bond, and property markets. Last but not least, it has increased moral hazard for governments, which have gone further into debt without difficulty. At the same time, central bank independence was violated, which has caused an abnormal increase in the central banks’ balance sheets. We, therefore, recommend that this unconventional monetary policy instrument should only be used in the short term for emergency situations as a clear central bank

Production of Long Chain Fatty Alcohols Found in Bumblebee Pheromones by Yarrowia lipolytica

Fatty alcohols (FA-OH) are aliphatic unbranched primary alcohols with a chain of four or more carbon atoms. Besides potential industrial applications, fatty alcohols have important biological functions as well. In nature, fatty alcohols are produced as a part of a mixture of pheromones in several insect species, such as moths, termites, bees, wasps, etc. In addition, FA-OHs have a potential for agricultural applications, for example, they may be used as a suitable substitute for commercial insecticides. The insecticides have several drawbacks associated with their preparation, and they exert a negative impact on the environment. Currently, pheromone components are prepared mainly through the catalytic hydrogenation of plant oils and petrochemicals, which is an unsustainable, ecologically unfriendly, and highly expensive process. The biotechnological production of the pheromone components using engineered microbial strains and through the expression of the enzymes participating in the biosynthesis of these components is a promising approach that ensures ecological sustenance as well. The present study was aimed at evaluating the production of FA-OHs in the oleaginous yeast, Yarrowia lipolytica, with different lengths of fatty-acyl chains by expressing the fatty acyl-CoA reductase (FAR) BlapFAR4 from B. lapidarius, producing C16:0-OH, C16:1Δ9-OH, and lower quantities of both C14:0-OH and C18:1Δ9-OH, and BlucFAR1 from B. lucorum, producing FA-OHs with a chain length of 18–26 carbon atoms, in this yeast. Among the different novel Y. lipolytica strains used in the present study, the best results were obtained with JMY7086, which carried several lipid metabolism modifications and expressed the BlucFAR1 gene under the control of a strong constitutive promoter 8UAS-pTEF. JMY7086 produced only saturated fatty alcohols with chain lengths from 18 to 24 carbon atoms. The highest titer and accumulation achieved were 166.6 mg/L and 15.6 mg/g DCW of fatty alcohols, respectively. Unlike JMY7086, the BlapFAR4-expressing strain JMY7090 produced only 16 carbon atom-long FA-OHs with a titer of 14.6 mg/L