Quantum information transfer from spin to orbital angular momentum of photons

The optical "spin-orbit" coupling occurring in a suitably patterned nonuniform birefringent plate known as `q-plate' allows entangling the polarization of a single photon with its orbital angular momentum (OAM). This process, in turn, can be exploited for building a bidirectional "spin-OAM interface", capable of transposing the quantum information from the spin to the OAM degree of freedom of photons and \textit{vice versa}. Here, we experimentally demonstrate this process by single-photon quantum tomographic analysis. Moreover, we show that two-photon quantum correlations such as those resulting from coalescence interference can be successfully transferred into the OAM degree of freedom.Comment: 4 pages, 4 figure

Erythema gyratum perstans: association with a familial neurologic disease.

Two members of the same family with erythema gyratum perstans and hypertrophic neuritis are reported. The dermatosis could be an expression of localization of neuritis to nerva vasorum with abnormal neurovascular response of cutaneous small vessels to normal stimuli with active erythema followed by cyanosis

Acquired hypertrichosis lanuginosa: a case report.

The authors present a patient with hypertrichosis lanuginosa acquisita without associated malignancy

Dynamical moments reveal a topological quantum transition in a photonic quantum walk

Many phenomena in solid-state physics can be understood in terms of their topological properties. Recently, controlled protocols of quantum walks are proving to be effective simulators of such phenomena. Here we report the realization of a photonic quantum walk showing both the trivial and the non-trivial topologies associated with chiral symmetry in one-dimensional periodic systems, as in the Su-Schrieffer-Heeger model of polyacetylene. We find that the probability distribution moments of the walker position after many steps behave differently in the two topological phases and can be used as direct indicators of the quantum transition: while varying a control parameter, these moments exhibit a slope discontinuity at the transition point, and remain constant in the non-trivial phase. Extending this approach to higher dimensions, different topological classes, and other typologies of quantum phases may offer new general instruments for investigating quantum transitions in such complex systems

First-Line Chemotherapy for HER-2–Negative Metastatic Breast Cancer Patients Who Received Anthracyclines as Adjuvant Treatment

Learning Objectives After completing this course, the reader will be able to: Discuss the value of retreatment with anthracyclines for HER-2–negative metastatic breast cancer patients who received anthracyclines as adjuvant treatment.Discuss the role of liposomal anthracyclines, taxanes, and combinations without anthracyclines and taxanes, or innovative treatments, including target-based agents.Comment on the weakness and quality of available evidence. Access and take the CME test online and receive 1 AMA PRA Category 1 Credit™ at CME.TheOncologist.co

Evaluation of efficacy and safety of new high-density dyes for chromovitrectomy

The purpose of this study is to evaluate the safety and efficacy of two novel heavy dyes for macular surgery: DoubledyneTM and TwinTM. One eye from each of 144 patients undergoing surgery for macular hole or macular pucker was included in the study. The eyes were randomly divided into two groups according to the dye used during surgery. Best correct visual acuity (BCVA), intraocular pressure (IOP) and retinal morphology assessed by ocular coherence tomography (OCT) were evaluated before and 1, 3, 6 and 12 months after surgery. Only one surgeon performed each operation and provided a score ranging from 1 (poor) to 10 (excellent) for quality of staining and comfort in surgery. Statistical analysis was carried out with SPSS to compare parameters before and after surgery and between the two groups. No statistical differences were recorded in quality of staining (p = 0.11), in surgery comfort (p = 0.17) and total time of surgery (p = 0.44) between the two groups. BCVA statistically improved and central macular thickness (CMT) statistically decreased after surgery in both groups (p < 0.05). No toxic dye-related complications or long-term ones affecting the retina were observed in either group. According to this data, although confirmation in further studies with larger populations and longer follow up is required, DoubledyneTM and TwinTM proved to be safe and effective dyes for macular surgery

Non-asymptotic Heisenberg scaling: experimental metrology for a wide resources range

Adopting quantum resources for parameter estimation discloses the possibility to realize quantum sensors operating at a sensitivity beyond the standard quantum limit. Such approach promises to reach the fundamental Heisenberg scaling as a function of the employed resources $N$ in the estimation process. Although previous experiments demonstrated precision scaling approaching Heisenberg-limited performances, reaching such regime for a wide range of $N$ remains hard to accomplish. Here, we show a method which suitably allocates the available resources reaching Heisenberg scaling without any prior information on the parameter. We demonstrate experimentally such an advantage in measuring a rotation angle. We quantitatively verify Heisenberg scaling for a considerable range of $N$ by using single-photon states with high-order orbital angular momentum, achieving an error reduction greater than $10$ dB below the standard quantum limit. Such results can be applied to different scenarios, opening the way to the optimization of resources in quantum sensing

Optimizing quantum-enhanced Bayesian multiparameter estimation of phase and noise in practical sensors

Achieving quantum-enhanced performances when measuring unknown quantities requires developing suitable methodologies for practical scenarios, which include noise and the availability of a limited amount of resources. Here, we report on the optimization of substandard quantum limit Bayesian multiparameter estimation in a scenario where a subset of the parameters describes unavoidable noise processes in an experimental photonic sensor. We explore how the optimization of the estimation changes depending on which parameters are either of interest or are treated as nuisance ones. Our results show that optimizing the multiparameter approach in noisy apparata represents a significant tool to fully exploit the potential of practical sensors operating beyond the standard quantum limit for broad resources range

Optimizing quantum-enhanced Bayesian multiparameter estimation in noisy apparata

Achieving quantum-enhanced performances when measuring unknown quantities requires developing suitable methodologies for practical scenarios, that include noise and the availability of a limited amount of resources. Here, we report on the optimization of quantum-enhanced Bayesian multiparameter estimation in a scenario where a subset of the parameters describes unavoidable noise processes in an experimental photonic sensor. We explore how the optimization of the estimation changes depending on which parameters are either of interest or are treated as nuisance ones. Our results show that optimizing the multiparameter approach in noisy apparata represents a significant tool to fully exploit the potential of practical sensors operating beyond the standard quantum limit for broad resources range

Amyotrophic Lateral Sclerosis and Multiple Sclerosis Overlap: A Case Report

The concurrence of amyotrophic lateral sclerosis (ALS) and multiple sclerosis (MS) is extremely rare. We reported the case of a 33-year-old woman with a past history of paresthesias at the right hand, who developed progressive quadriparesis with muscular atrophy of limbs and, finally, bulbar signs and dyspnea. Clinical and neurophysiologic investigations revealed upper and lower motor neuron signs in the bulbar region and extremities, suggesting the diagnosis of ALS. Moreover, magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) analysis demonstrated 3 periventricular and juxtacortical lesions, hyperintense in T2 and FLAIR sequences, and 3 liquoral immunoglobulin G (IgG) oligoclonal bands, consistent with diagnosis of primary progressive MS (PPMS). This unusual overlap of ALS and MS leads to the discussion of a hypothetical common pathological process of immunological dysfunction in these two disorders, although the role of immune response in ALS remains ambivalent and unclear