The Rebirth of Airships

Until the outbreak of the Second World War, uncertainty existed whether airships and airplanes would dominate intercontinental passenger transportation. The massive investments in fixed-wing aircraft during these hostilities made airplanes the decisive winner, and relegated airships to a negligible role in transportation. As the 21st Century progresses, airships are making a comeback fueled by the 21st Century progresses, airships are making a comeback fueled by the growing demand for air cargo, the unique environmental and operational characteristics of buoyant flight, and advances in engineering science and materials. This paper examines the market niche for airships that exists between air and marine transport and the inherent advantages and disadvantages of this mode of transportation. The economics of airships are considered in light of their past achievements and current designs. The paper concludes with the discussion of two potential applications. A long haul mission for airships between Hawaii and the U.S. mainland is considered for perishable freight, and a short haul mission for airships in northern Canada is considered for the transport of freight and passengers to remote communities

The Dutchman Vol. 6, No. 2

● Spatterware ● That\u27s a Lot of Boloney ● A Dutch Touch ● Birds in Dutchland ● Cornelius Weygandt Day ● Brick-end Barns ● Hardly Bigger Than a Peanut ● Pennsylvania Dutch Pioneers ● Sycamores in Dutchland ● The Zehn-uhr Schtickhttps://digitalcommons.ursinus.edu/dutchmanmag/1001/thumbnail.jp

Relativistic effects and quasipotential equations

We compare the scattering amplitude resulting from the several quasipotential equations for scalar particles. We consider the Blankenbecler-Sugar, Spectator, Thompson, Erkelenz-Holinde and Equal-Time equations, which were solved numerically without decomposition into partial waves. We analyze both negative-energy state components of the propagators and retardation effects. We found that the scattering solutions of the Spectator and the Equal-Time equations are very close to the nonrelativistic solution even at high energies. The overall relativistic effect increases with the energy. The width of the band for the relative uncertainty in the real part of the scattering $T$ matrix, due to different dynamical equations, is largest for backward-scattering angles where it can be as large as 40%.Comment: Accepted for publication in Phys. Rev.

Development of a Protocol for Obtaining Biological Samples for Genetic Testing from Remote Individuals

Pharmacogenomic sequencing allows individuals to learn more about how they will respond to certain medications but requires shipping of a biological sample. One complication of sending biological samples to remote laboratories is stability. Blood generally yields sufficient quantities of high-quality DNA but requires a clinic visit. Saliva and buccal swabs are routinely used for DNA extractions, but the DNA quality is notoriously low due to the presence of bacteria in the mouth. Additionally, elderly individuals have difficulty producing enough saliva for testing, and the tubes contain several milliliters of liquid and shipping requires special considerations. Dried blood spot cards, which serve as an alternative to saliva and buccal swabs, yield high-quality DNA and ship easily, but may produce a lower yield. This project aims to determine which biological sample methods can reasonably be obtained from remote individuals

Two-year follow-up of the phase II marker lesion study of intravesical apaziquone for patients with non-muscle invasive bladder cancer

Item does not contain fulltextOBJECTIVES: To study the time-to-recurrence and duration of response in non-muscle invasive bladder cancer (NMIBC) patients, with a complete ablative response after intravesical apaziquone instillations. METHODS: Transurethral resection of bladder tumour(s) (TURBT) was performed in patients with multiple pTa-T1 G1-2 urothelial cell carcinoma (UCC) of the bladder, with the exception of one marker lesion of 0.5-1.0 cm. Intravesical apaziquone was administered at weekly intervals for six consecutive weeks, without maintenance instillations. A histological confirmed response was obtained 2-4 weeks after the last instillation. Routine follow-up (FU) was carried out at 6, 9, 12, 18 and 24 months from the first apaziquone instillation. RESULTS: At 3 months FU 31 of 46 patients (67.4%) had a complete response (CR) to ablative treatment. Side-effects on the long-term were only mild. Two CR patients dropped out during FU. On intention-to-treat (ITT) analysis 49.5% of the CR patients were recurrence-free at 24 months FU, with a median duration of response of 18 months. Of 15 no response (NR) patients, only two received additional prophylactic instillations after TURBT. On ITT-analysis 26.7% of the NR patients were recurrence-free (log rank test, P = 0.155). The overall recurrence-free survival was 39% (18 of 46 patients) at 24 months FU. CONCLUSIONS: The CR of the marker lesion in 67% of patients was followed by a recurrence-free rate of 56.5% at 1-year FU, and 49.5% at 2-year FU. These long-term results are good in comparison with the results of other ablative studies