Investigation of the active Celano-L'Aquila fault system, Abruzzi (central Apennines, Italy) with combined ground-penetrating radar and palaeoseismic trenching

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Novelty of Italian Grape Ale (IGA) beer: Influence of the addition of Gamay macerated grape must or dehydrated Aleatico grape pomace on the aromatic profile

: A new category of fruit style beer resulting from the addition of grape matrices is named Italian Grape Ale (IGA). In this paper, we report data on an experimental work to produce IGA beers, adding macerated (CO2 or N2) red Gamay grape must or Aleatico grape pomace resulting from a grape dehydration process. Our hypothesis, that these wine processes can produce volatile organic compounds (VOCs) to characterize these IGA beers which was confirmed by chemical, sensory and aromatic results. IGA beers especially the one with gas-macerated grape musts (IGA-C and IGA-N) showed higher alcohol content than ALE beer (Control) and a higher polyphenol content and antioxidant activity. As regards VOCS, IGA beers increased the concentration of some classes (i.e., alcohols, esters, norisoprenoids) and IGA-N was better characterized by specific compounds such as isobutyric acid, phenylacetate, tyrosol, ethyl hydrogen succinate. Finally, E-nose and sensory evaluation discriminated significantly all the IGA beers

Electromagnetic propagation features of ground-penetrating radars for the exploration of Martian subsurface

In this work, the effects of magnetic inclusions in a Mars-like soil are considered with reference to the electromagnetic propagation features of ground-penetrating radars (GPRs). Low-frequency and time-domain techniques, using L-C-R meters and TDR instruments, respectively, are implemented in laboratory experimental set-ups in order to evaluate complex permittivity and permeability and wave velocity for different scenarios of a dielectric background medium (silica) with magnetic inclusions (magnetite). Attenuation and maximum detection ranges have also been evaluated by taking into account a realistic GPR environment, which includes the transmitting/receiving antenna performance and the complex structure of the subsurface. The analysis and the interpretation of these results shed new light on the significant influence of magnetic inclusions on the performance of Martian orbiting and rover-driven GPRs.Published5-11reserve

Reply to: Explaining bright radar reflections below the south pole of Mars without liquid water

In their Matter Arising Lalich et al.1 simulate MARSIS echoes at the base of the South Polar Layered Deposits (SPLD) assuming three different layering scenarios (Fig. 1 in ref.1): (a) dusty water ice overlaying bedrock; (b) one CO2 ice layer between dusty water ice and bedrock; and, (c) two basal CO2 ice layers interbedded with one layer of dusty water ice. A surficial layer of CO2 ice ranging from 0 m (no layer) to 2 m in thickness is also considered. The first layer in each simulation is a semi-infinite half space assigned the permittivity of free space, and the bedrock is a semi-infinite half space with pure basaltic rock permittivity. These authors argue that constructive interference generated by some layered configurations produce waveforms (Fig. 2 in ref.1) with local maxima corresponding to the bright basal reflections observed by MARSIS at Ultimi Scopuli 2,3. They conclude that this explanation is more plausible than liquid brines being the source of the bright reflections, as posited instead by Orosei et al.2 and Lauro et al.3. In an earlier paper, however, Orosei et al.4 explored the same model and mathematics covering the entire range of possible parameters for two and three basal CO2 ice layers. Through the quantitative analysis of 3.45 x 108 simulation results, these authors demonstrated that local maxima at one of the MARSIS operating frequencies are not matched by local maxima at the other operating frequencies: that is, a layer stack producing constructive interference at one frequency, does not produce the same effect at the other frequencies, which is inconsistent with MARSIS real data. Thus, constructive interference by basal layers is not a viable mechanism to explain the bright basal reflections at Ultimi Scopuli. Because most of the points in Lalich et al.1 are superseded by Orosei et al.’s4 work, we refer interested readers to that earlier paper for a full discussion of the models and results. Here, we focus on three critical aspects: electromagnetic model; dielectric values used in the simulations; and materials and geology

Radar Evidence of Subglacial Liquid Water on Mars

Strong radar echoes from the bottom of the martian southern polar deposits are interpreted as being due to the presence of liquid water under 1.5 km of ice

Ammonite stratigraphy of a Toarcian (Lower Jurassic) section on Nagy-Pisznice Hill (Gerecse Mts, Hungary)

Abstract In the Jurassic rocks exposed in a small abandoned quarry on the northwestern edge of Nagy-Pisznice Hill in the Gerecse Mts, fairly well preserved parts of a crocodile skeleton was found in 1996. The bed which yielded the skeletal remains is the uppermost layer of the Kisgerecse Marl Formation exposed here and was determined as belonging to the Upper Toarcian Grammoceras thouarsense Zone. The beds of the sequence above and below were carefully sampled in the late 1990s, and the encountered ammonites were evaluated biostratigraphically. As a result, the Lower Toarcian Harpoceras serpentinum Zone, the Middle Toarcian Hildoceras bifrons and Merlaites gradatus Zones, and the Upper Toarcian Grammoceras thouarsense and Geczyceras speciosum Zones were identified. Within most of these zones the subzones and even the faunal horizons were successfully recognized. The lowermost beds above the underlying Pliensbachian red limestone did not yield any fossils; thus the lowermost Toarcian Dactylioceras tenuicostatum Zone could not be documented. The highest Toarcian ammonite zones also remained unidentified, because the beds of the Tölgyhát Limestone above were not sampled all the way up. This paper presents the lithostratigraphic and biostratigraphic details of the sequence, and the paleontological descriptions of the most important ammonites

Soil Moisture and Permittivity Estimation

The soil moisture and permittivity estimation is vital for the success of the variable rate approaches in the field of the decision agriculture. In this chapter, the development of a novel permittivity estimation and soil moisture sensing approach is presented. The empirical setup and experimental methodology for the power delay measurements used in model are introduced. Moreover, the performance analysis is explained that includes the model validation and error analysis. The transfer functions are reported as well for soil moisture and permittivity estimation. Furthermore, the potential applications of the developed approach in different disciplines are also examined

Risk of hospitalization for heart failure in patients with type 2 diabetes newly treated with DPP-4 inhibitors or other oral glucose-lowering medications: A retrospective registry study on 127,555 patients from the Nationwide OsMed Health-DB Database

Aims Oral glucose-lowering medications are associated with excess risk of heart failure (HF). Given the absence of comparative data among drug classes, we performed a retrospective study in 32 Health Services of 16 Italian regions accounting for a population of 18 million individuals, to assess the association between HF risk and use of sulphonylureas, DPP-4i, and glitazones. Methods and results We extracted data on patients with type 2 diabetes who initiated treatment with DPP-4i, thiazolidinediones, or sulphonylureas alone or in combination with metformin during an accrual time of 2 years. The endpoint was hospitalization for HF (HHF) occurring after the first 6 months of therapy, and the observation was extended for up to 4 years. A total of 127 555 patients were included, of whom 14.3% were on DPP-4i, 72.5% on sulphonylurea, 13.2% on thiazolidinediones, with average 70.7% being on metformin as combination therapy. Patients in the three groups differed significantly for baseline characteristics: age, sex, Charlson index, concurrent medications, and previous cardiovascular events. During an average 2.6-year follow-up, after adjusting for measured confounders, use of DPP-4i was associated with a reduced risk of HHF compared with sulphonylureas [hazard ratio (HR) 0.78; 95% confidence interval (CI) 0.62-0.97; P = 0.026]. After propensity matching, the analysis was restricted to 39 465 patients, and the use of DPP-4i was still associated with a lower risk of HHF (HR 0.70; 95% CI 0.52-0.94; P = 0.018). Conclusion In a very large observational study, the use of DPP-4i was associated with a reduced risk of HHF when compared with sulphonylureas

Isolation and Characterization of New Leptospira Genotypes from Patients in Mayotte (Indian Ocean)

Leptospirosis has been recognized as an increasing public health problem affecting poor people from developing countries and tropical regions. However, the epidemiology of leptospirosis remains poorly understood in remote parts of the world. In this study of patients from the island of Mayotte, we isolated 22 strains from the blood of patients during the acute phase of illness. The pathogenic Leptospira strains were characterized by serology and various molecular typing methods. Based on serological data, serogroup Mini appears to be the dominant cause of leptospirosis in Mayotte. Further molecular characterization of these isolates allowed the identification of 10 pathogenic Leptospira genotypes that could correspond to previously unknown serovars. Further progress in our understanding of the epidemiology of Leptospira circulating genotypes in highly endemic regions should contribute to the development of novel strategies for the diagnosis and prevention of this neglected emerging disease