1,539 research outputs found

    The Problem of Personal Immortality.

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    Architekturströmungen der Gegenwart in der Bundesrepublik Deutschland am Beispiel der Bundeshauptstadt Bonn

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    Wissenschaftliches Kolloquium vom 24. bis 26. Juni 1986 in Weimar an der Hochschule für Architektur und Bauwesen zum Thema: 'Der wissenschaftlich-technische Fortschritt und die sozial-kulturellen Funktionen von Architektur und industrieller Formgestaltung in unserer Epoche

    Measuring dark matter by modeling interacting galaxies

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    The dark matter content of galaxies is usually determined from galaxies in dynamical equilibrium, mainly from rotationally supported galactic components. Such determinations restrict measurements to special regions in galaxies, e.g. the galactic plane(s), whereas other regions are not probed at all. Interacting galaxies offer an alternative, because extended tidal tails often probe outer or off-plane regions of galaxies. However, these systems are neither in dynamical equilibrium nor simple, because they are composed of two or more galaxies, by this increasing the associated parameter space.We present our genetic algorithm based modeling tool which allows to investigate the extended parameter space of interacting galaxies. From these studies, we derive the dynamical history of (well observed) galaxies. Among other parameters we constrain the dark matter content of the involved galaxies. We demonstrate the applicability of this strategy with examples ranging from stellar streams around theMilkyWay to extended tidal tails, from proto-typical binary galaxies (like M51 or the Antennae system) to small group of galaxies.Comment: 4 pages, 3 figures, Conf.: Hunting for the dark, Malta 200

    Zum Wohnungsbau der 50er Jahre in der Bundesrepublik Deutschland

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    Wissenschaftliches Kolloquium vom 5. bis 7. Juli 1983 in Weimar an der Hochschule für Architektur und Bauwesen zum Thema: 'Das Bauhauserbe und die gegenwärtige Entwicklung der Architektur : zum 100. Geburtstag von Walter Gropius

    Modeling and visualizing urban sprawl and carbon footprints in Phoenix metropolitan area

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    Urban planners are dealing with problems of urban sprawl and CO2 emissions. The multidimensional character of these phenomena requires new analysis and visualization tools that are unavailable in platforms like the Geographical Information Systems (GIS). This paper, first, presents an approach for measuring and monitoring urban sprawl and carbon footprints. Second, it offers a three-dimensional visualization method that takes into account the multi-dimensional nature of the data. The visualization of the data is based on an intuitive approach involving B-Splines and Bezier techniques to create three-dimensional surfaces. Finally the paper introduces an analysis tool for planners and decision makers to examine household carbon footprints in relation to their direct spatial neighborhood based on unstructured census data

    Genome-Wide Analysis of leafbladeless1-Regulated and Phased Small RNAs Underscores the Importance of the TAS3 ta-siRNA Pathway to Maize Development

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    Maize leafbladeless1 (lbl1) encodes a key component in the trans-acting short-interfering RNA (ta-siRNA) biogenesis pathway. Correlated with a great diversity in ta-siRNAs and the targets they regulate, the phenotypes conditioned by mutants perturbing this small RNA pathway vary extensively across species. Mutations in lbl1 result in severe developmental defects, giving rise to plants with radial, abaxialized leaves. To investigate the basis for this phenotype, we compared the small RNA content between wild-type and lbl1 seedling apices. We show that LBL1 affects the accumulation of small RNAs in all major classes, and reveal unexpected crosstalk between ta-siRNA biogenesis and other small RNA pathways regulating transposons. Interestingly, in contrast to data from other plant species, we found no evidence for the existence of phased siRNAs generated via the one-hit model. Our analysis identified nine TAS loci, all belonging to the conserved TAS3 family. Information from RNA deep sequencing and PARE analyses identified the tasiR-ARFs as the major functional ta-siRNAs in the maize vegetative apex where they regulate expression of AUXIN RESPONSE FACTOR3 (ARF3) homologs. Plants expressing a tasiR-ARF insensitive arf3a transgene recapitulate the phenotype of lbl1, providing direct evidence that deregulation of ARF3 transcription factors underlies the developmental defects of maize ta-siRNA biogenesis mutants. The phenotypes of Arabidopsis and Medicago ta-siRNA mutants, while strikingly different, likewise result from misexpression of the tasiR-ARF target ARF3. Our data indicate that diversity in TAS pathways and their targets cannot fully account for the phenotypic differences conditioned by ta-siRNA biogenesis mutants across plant species. Instead, we propose that divergence in the gene networks downstream of the ARF3 transcription factors or the spatiotemporal pattern during leaf development in which these proteins act constitute key factors underlying the distinct contributions of the ta-siRNA pathway to development in maize, Arabidopsis, and possibly other plant species as well

    Adjuvant effects of a sequence-engineered mRNA vaccine: translational profiling demonstrates similar human and murine innate response

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    Additional file 1: Fig. S1. Components and assembly of the PTE module for innate responses. (A) Top panel—in vivo monocytes continuously emigrate from the blood into peripheral tissues with a half-life in the blood of ~1 day. Bottom panel: In vitro generation of cytokine derived DCs from monocytes involves the addition of IL-4 and GM-CSF and culture for 7–11 days. (B) Schematic of the components of a MIMIC-PTE module. In the 3D PTE, differentiation occurs in hours to about 2 days triggered by migration into and out of (reverse migration) through the endothelium: a process reminiscent of the movement of cells from tissues into lymphatic vessels

    How Do Non-Formal Environmental Education Experiences Shape Pro-Environmental Behavior

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    This paper attempts to define what behaviors are, what motivates behavior, and how environmental education programs can shape pro-environmental behavior using three factors: social interaction, program structure, and various teaching methods. Data was gathered using a systematic literature review that looked at the purpose and objectives of the paper, methods used for collecting data such as demographics (age, race, gender, location, etc.), the papers focused areas of research, and results. A thematic analysis was also used to code collected data into the themes. The themes that emerged while analyzing the data include social interactions, program structure, and teaching methods. Results conclude that while not everyone learns the same way having programs with social settings that create a sense of community, developmentally appropriate content and various learning methods can help create a positive experience which leads to pro-environmental behaviors. Allowing students to interact with their local environment using various teaching methods can allow children to take on leadership roles, learn problem-solving skills, learn to critically think and build teamwork skills. These are valuable skills to have and will set the child up for success in the future

    Ibsen\u27s Life-Forms.

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