44 research outputs found
Broiler meat quality: Proteins and lipids of muscle tissue
Proteins and lipids of muscle tissue are important meat quality parameters. They contribute substantially to the nutritional characteristics of meat. A number of studies has been conducted on the effect of different factors on the protein and lipid content of broiler meat. Given the above, the subjectmatter of the present paper was to provide a review of latest research results on the said quality traits as affected by the most commonly tested factors. The results were grouped and presented in terms of the effect of nutrition, genotype, sex, age and rearing system. The objective of the paper was to review major previous studies on the subject in an attempt to define a future research pathway and facilitate the promotion of scientific findings towards wider practical implementation.Keywords: Broilers, meat quality, proteins, lipid
The evolution of multiple active site configurations in a designed enzyme
Developments in computational chemistry, bioinformatics, and laboratory evolution have facilitated the de novo design and catalytic optimization of enzymes. Besides creating useful catalysts, the generation and iterative improvement of designed enzymes can provide valuable insight into the interplay between the many phenomena that have been suggested to contribute to catalysis. In this work, we follow changes in conformational sampling, electrostatic preorganization, and quantum tunneling along the evolutionary trajectory of a designed Kemp eliminase. We observe that in the Kemp Eliminase KE07, instability of the designed active site leads to the emergence of two additional active site configurations. Evolutionary conformational selection then gradually stabilizes the most efficient configuration, leading to an improved enzyme. This work exemplifies the link between conformational plasticity and evolvability and demonstrates that residues remote from the active sites of enzymes play crucial roles in controlling and shaping the active site for efficient catalysis
FFLO-wave-vector Lock-in Effect in Quasi-1D Superconductors
We study the phase transition into the Fulde-Ferrell-Larkin-Ovchinnikov state in high magnetic field in quasi-one dimensional superconductors within the quasi-classical formalism, taking into account the interchain Josephson coupling and the paramagnetic spin splitting. We show that anomalies in the field-direction dependence of the upper critical field when the magnetic field length equals to the FFLO period, previously described in [29], are characterized by the lock-in effect of the FFLO modulation wave vector, which is governed by the magnetic length.Des nanosondes ultra-sensibles pour explorer les distributions de charges électriques dans les supraconducteur