Numerical simulation of 3D free surface flows in time dependent curvilinear coordinates

We propose a three dimensional non-hydrostatic shock-capturing numerical model for the simulation of wave propagation, transformation and breaking, which is based on an original integral formulation of the contravariant Navier-Stokes equations, devoid of Christoffel symbols, in general time-dependent curvilinear coordinates

Electromyoneurography and laboratory findings in a case of Guillain-Barré syndrome after second dose of Pfizer COVID-19 vaccine

Guillain-Barre syndrome (GBS) is an acute immune-mediated disease of the peripheral nerves and nerve roots (polyradiculoneuropathy) that is usually elicited by various infections. We present a case of GBS after receiving the second dose of Pfizer-COVID 19 vaccine. Diagnosis was made after performing an accurate clinical examination, electromyoneurography and laboratory tests. In particular, anti-ganglioside antibo-dies have tested positive. During this pandemic with ongoing worldwide mass vaccination campaign, it is critically important for clinicians to rapidly recognize neurological complications or other side effects associated with COVID-19 vaccinatio

Lipomatous hypertrophy: an accidental finding in heart

Lipomatous hypertrophy is an uncommon benign lesion of the atrium, generally asymptomatic, characterized by unencapsulated accumulation of adipose tissue entrapping cardiomyocytes. This pathology generally remains unnoticed and often emerges as an occasional finding. Here, we report two cases from our hospital including a review of the available literature

User-centred design of flexible hypermedia for a mobile guide: Reflections on the hyperaudio experience

A user-centred design approach involves end-users from the very beginning. Considering users at the early stages compels designers to think in terms of utility and usability and helps develop the system on what is actually needed. This paper discusses the case of HyperAudio, a context-sensitive adaptive and mobile guide to museums developed in the late 90s. User requirements were collected via a survey to understand visitors’ profiles and visit styles in Natural Science museums. The knowledge acquired supported the specification of system requirements, helping defining user model, data structure and adaptive behaviour of the system. User requirements guided the design decisions on what could be implemented by using simple adaptable triggers and what instead needed more sophisticated adaptive techniques, a fundamental choice when all the computation must be done on a PDA. Graphical and interactive environments for developing and testing complex adaptive systems are discussed as a further step towards an iterative design that considers the user interaction a central point. The paper discusses how such an environment allows designers and developers to experiment with different system’s behaviours and to widely test it under realistic conditions by simulation of the actual context evolving over time. The understanding gained in HyperAudio is then considered in the perspective of the developments that followed that first experience: our findings seem still valid despite the passed time

Expression of the endocannabinoid receptors in human fascial tissue.

open7noCannabinoid receptors have been localized in the central and peripheral nervous system as well as on cells of the immune system, but recent studies on animal tissue gave evidence for the presence of cannabinoid receptors in different types of tissues. Their presence was supposed also in myofascial tissue, suggesting that the endocannabinoid system may help resolve myofascial trigger points and relieve symptoms of fibromyalgia. However, until now the expression of CBI (cannabinoid receptor I) and CB2 (cannabinoid receptor 2) in fasciae has not yet been established. Small samples of fascia were collected from volunteers patients during orthopedic surgery. For each sample were done a cell isolation, immunohistochemical investigation (CB1 and CB2 antibodies) and real time RT-PCR to detect the expression of CB1 and CB2. Both cannabinoid receptors are expressed in human fascia and in human fascial fibroblasts culture cells. although to a lesser extent than the control gene. We can assume that the expression of mRNA and protein of CBI and CB2 receptors in fascial tissue are concentrated into the fibroblasts This is the first demonstration that the fibroblasts of the muscular fasciae express CBI and CB2. The presence of these receptors could help to provide a description of cannabinoid receptors distribution and to better explain the role of fasciae as pain generator and the efficacy of some fascial treatments. Indeed the endocannabinoid receptors of fascial fibroblasts can contribute to modulate the fascial fibrosis and inflammation.noneopenFede, C; Albertin, G; Petrelli, L; Sfriso, Mm; Biz, C; De Caro, R; Stecco, CFede, C; Albertin, Giovanna; Petrelli, Lucia; Sfriso, MARIA MARTINA; Biz, Carlo; DE CARO, Raffaele; Stecco, Carl

Fragmentation, Factorization and Infrared Poles in Heavy Quarkonium Production

We explore the role of soft gluon exchange in heavy quarkonium production at large transverse momentum. We find uncanceled infrared poles at NNLO that are not matched by conventional NRQCD matrix elements. We show, however, that gauge invariance and factorization require that conventional NRQCD production operators be modified to include nonabelian phases or Wilson lines. With appropriately modified operators, factorization is restored at NNLO. We also argue that, in the absence of special cancellations, infrared poles at yet higher orders may require the inclusion of additional nonlocal operators, not present in the NRQCD expansion in relative veloctiy.Comment: 10 pages latex, 6 eps figure

The diet of otters (Lutra lutra) on the Agri river system, one of the most important presence sites in Italy: A molecular approach

Background. The Eurasian otter (Lutra lutra) underwent a strong decline in large areas of the Central-Western part of its distribution range, during the second half of the twentieth century. In Italy, only residual fragmented nuclei survive in the Central- Southern part of the peninsula. Nowadays, the otter is one of the most endangered mammals in Italy, and increasing the knowledge about the ecology of this species is a key step in defining fitting management strategies. Here we provide information about the diet of otter on the Agri river system, one of the most important presence sites in Italy, to understand both the species' food requirements and the impact on fish communities. Methods. DNA metabarcoding and High Throughput Sequencing were used on DNA extracted from spraints. We amplified DNA with a primer set for vertebrates, focusing efforts on the bulk of the otter's diet (fishes and amphibians). Results. Our findings showed that the diet of the otter was dominated by cyprinids (97.77%, and 99.14% of fishes), while amphibians represented 0.85% of the sequences analyzed. Results are in general accordance with previous studies based on morphological characterization; however, molecular analyses allow the resolving of some morphological uncertainties. Although the study area offers a very wide range of available prey, the diet of the otters shows marked selectivity. We highlighted a variation in prey consumed, in accordance with the typology of water system (i.e., river, lake, tributary). Some of the preys found in the diet were alien species introduced by man for sport fishing. Our findings could help define strategies useful for the conservation of the otter population in Southern Italy, suggesting management actions directed at avoiding fish community alterations through illegal stockings without severe controls on their taxonomic status. These introductions could result in a general reduction in the diversity of the otter's preys, affecting its predatory behavior

Substance use and knowledge among Italian High School students.

This study was aimed for evaluation of Italian students' attitudes to addictive substances, their knowledge and personal experience, and their awareness about the risks. The research was realized among high school students from Marche region in the Central Italy in the year 2006; the study group was randomly chosen from all schools in the region. 4118 appropriately completed questionnaires returned. The statistic processing was carried out by using chi-square test for two qualitative variables. 29.9 % of the students have tried drugs; 36.4 % of the interviewed reckon alcohol, tobacco and antidepressants for drugs. A relationship between the use of licit and illicit addictive substances and a correlation between the use of illicit substances and the use of liquors and tobacco in family was found. The students, who drink frequently, smoke regularly and use drugs, believe that the drugs create dependence only if overused; only a quarter of them classify themselves as drug addicts. The study indicates a lack of information on the drugs among the young people. It emerges that the young people do not sufficiently know the risk of the dependence. A change of the preventive strategies should be considered

Oviposition inhibitory activity of the Mexican sunflower Tithonia diversifolia (Asteraceae) polar extracts against the two-spotted spider mite Tetranychus urticae (Tetranychidae)

The Mexican sunflower (Tithonia diversifolia, Asteraceae) is an invasive shrub of agricultural and non-agricultural lands in tropical countries. Besides extensive utilizations in the traditional medicine, mainly to treat malaria, the plant is believed to have a great potential in agriculture of developing countries as a green biomass to produce fertilizer, fodder and biopesticides. The plant is known to produce tagitinins, which are sesquiterpene lactones with a bitter taste endowed with toxicity against several insects such as mosquitoes, aphids, and beetles. Here, we evaluated the potential of T. diversifolia against the two-spotted spider mite Tetranychus urticae (Tetranychidae), which is one of the most economically important arthropod pests worldwide. The leaf methanolic extract and its ethyl acetate fraction were tested for acute and chronic toxicity and for oviposition inhibitory effects. The chemical composition of the extracts was analyzed by HPLC-MSn and NMR. The main constituents were flavonoid derivatives, phenylpropanoids and sesquiterpene lactones. Among the latter, tagitinin C and tagitinin A were the major compounds. In acute toxicity assays, mortality did not exceed 50% even for the highest tested dose of 150 \u3bcg cm-3. However, in chronic toxicity assays, on day 5 from application, the methanolic extract LD50 was 41.3 \u3bcg cm-3 while LD90 was 98.7 \u3bcg cm-3. Furthermore, both T. diversifolia extracts inhibited oviposition in T. urticae. The ethyl acetate extract was the most active oviposition inhibitor, with an ED50 value of 44.3 \u3bcg cm-3 and an ED90 of 121.5 \u3bcg cm-3. Overall, the good yield rate of the extract and the high crop yield highlighted good prospects of using the extract from this plant for the development of oviposition inhibitors against mite

Report of the QCD Tools Working Group

We report on the activities of the ``QCD Tools for heavy flavors and new physics searches'' working group of the Run II Workshop on QCD and Weak Bosons. The contributions cover the topics of improved parton showering and comparisons of Monte Carlo programs and resummation calculations, recent developments in Pythia, the methodology of measuring backgrounds to new physics searches, variable flavor number schemes for heavy quark electro-production, the underlying event in hard scattering processes, and the Monte Carlo MCFM for NLO processes.Comment: LaTeX, 47 pages, 41 figures, 10 tables, uses run2col.sty, to appear in the Proceedings of the Workshop on "QCD and Weak Boson Physics in Run II", Fermilab, March - November 199