Season 2, Episode 4: An Appreciative Inquiry Narrative

Laël Ngangmeni (\u2723, MD/PhD) and Dr. Hugh Silk are joined by Ken Peterson, a family nurse practitioner and assistant professor in the Graduate School of Nursing, to reflect on his experience as a nurse during the HIV/AIDS epidemic. Recorded August 2021. Ken Peterson\u27s piece An Appreciative Inquiry Narrative and the transcript for this episode are available for download as additional files

Characterization of “Neo-Dermis” Formation Beneath Cultured Human Epidermal Autografts Transplanted on Muscle Fascia

Cultured human keratinocyte autografts were transplanted to burn wounds that had been completely excised down to muscle fascia such that all cutaneous elements were removed from the wounds. Healing autografts were biopsied from days 6-153 in five patients, and the "neo-dermis" beneath the autografts was examined by immunofluorescent staining using antibody probes to connective tissue molecules, by histochemical staining for elastin fibers, and by electron microscopy. We found that the neo-dermis contained most of the major connective tissue elements early in the post-transplantation period. However, regardless of the time examined, there was a paucity of elastin fibers and poor organization of linkin (microthread-like fibers) in the neo-dermis beneath autografts. The perturbations of these connective tissue components in the neo-dermis may play a role in the poor recoil and elastic properties of burn wounds treated with autografts

Planning guidelines for koala conservation and recovery: A guide to best planning practice

The information contained in the guide is a synthesis of four years research into the conservation and restoration of koala populations in fragmented landscapes of eastern Australia. The guidelines also capture a decade of practical research and planning experience by the Australian Koala Foundation in mapping koala habitat and developing koala conservation and management plans for local government areas in New South Wales. They draw on the collective knowledge of researchers who wanted to see their results put into action with practical outcomes for koala conservation

A Spectacular Hα\alpha Complex in Virgo: Evidence for a Collision Between M86 and NGC 4438 and Implications for Collisional ISM Heating of Ellipticals

Deep wide-field H$\alpha$+[NII] imaging around the Virgo cluster giant elliptical galaxy M86 reveals a highly complex and disturbed ISM/ICM. The most striking feature is a set of H$\alpha$ filaments which clearly connect M86 with the nearby disturbed spiral NGC 4438 (23$'$=120 kpc projected away), providing strong evidence for a previously unrecognized collision between them. Spectroscopy of selected regions show a fairly smooth velocity gradient between M86 and NGC 4438, consistent with the collision scenario. Such a collision would impart significant energy into the ISM of M86, probably heating the gas and acting to prevent the gas from cooling to form stars. We propose that cool gas stripped from NGC 4438 during the collision and deposited in its wake is heated by shocks, ram pressure drag, or thermal conduction, producing most of the H$\alpha$ filaments. Some H$\alpha$ filaments are associated with the well-known ridge of bright X-ray emission to the NW of the nucleus, suggesting that the collision is responsible for peculiarities of M86 previously ascribed to other effects. M86 is radio-quiet, thus AGN heating is unlikely to play a significant role. The M86 system has implications for understanding the role of gravitational interactions in the heating of the ISM in ellipticals, and how collisions in clusters transform galaxies.Comment: 6 pages, 2 figures. For high-resolution images, see http://www.astro.yale.edu/tal/research/index.htm

Assessing Psychological Well-Being: Self-Report Instruments for the NIH Toolbox

Objective— Psychological well-being (PWB) has a significant relationship with physical and mental health. As part of the NIH Toolbox for the Assessment of Neurological and Behavioral Function, we developed self-report item banks and short forms to assess PWB. Study Design and Setting— Expert feedback and literature review informed the selection of PWB concepts and the development of item pools for Positive Affect, Life Satisfaction, and Meaning and Purpose. Items were tested with a community-dwelling U.S. internet panel sample of adults aged 18 and above (N=552). Classical and item response theory (IRT) approaches were used to evaluate unidimensionality, fit of items to the overall measure, and calibrations of those items, including differential item function (DIF). Results— IRT-calibrated item banks were produced for Positive Affect (34 items), Life Satisfaction (16 items), and Meaning and Purpose (18 items). Their psychometric properties were supported based on results of factor analysis, fit statistics, and DIF evaluation. All banks measured the concepts precisely (reliability ≥0.90) for more than 98% of participants. Conclusion— These adult scales and item banks for PWB provide the flexibility, efficiency, and precision necessary to promote future epidemiological, observational, and intervention research on the relationship of PWB with physical and mental health

Disk-Jet Connection in the Radio Galaxy 3C 120

We present the results of extensive multi-frequency monitoring of the radio galaxy 3C 120 between 2002 and 2007 at X-ray, optical, and radio wave bands, as well as imaging with the Very Long Baseline Array (VLBA). Over the 5 yr of observation, significant dips in the X-ray light curve are followed by ejections of bright superluminal knots in the VLBA images. Consistent with this, the X-ray flux and 37 GHz flux are anti-correlated with X-ray leading the radio variations. This implies that, in this radio galaxy, the radiative state of accretion disk plus corona system, where the X-rays are produced, has a direct effect on the events in the jet, where the radio emission originates. The X-ray power spectral density of 3C 120 shows a break, with steeper slope at shorter timescale and the break timescale is commensurate with the mass of the central black hole based on observations of Seyfert galaxies and black hole X-ray binaries. These findings provide support for the paradigm that black hole X-ray binaries and active galactic nuclei are fundamentally similar systems, with characteristic time and size scales linearly proportional to the mass of the central black hole. The X-ray and optical variations are strongly correlated in 3C 120, which implies that the optical emission in this object arises from the same general region as the X-rays, i.e., in the accretion disk-corona system. We numerically model multi-wavelength light curves of 3C 120 from such a system with the optical-UV emission produced in the disk and the X-rays generated by scattering of thermal photons by hot electrons in the corona. From the comparison of the temporal properties of the model light curves to that of the observed variability, we constrain the physical size of the corona and the distances of the emitting regions from the central BH.Comment: Accepted for publication in the Astrophysical Journal. 28 pages, 21 figures, 2 table

Active adaptive conservation of threatened species in the face of uncertainty

Adaptive management has a long history in the natural resource management literature, but despite this, few practitioners have developed adaptive strategies to conserve threatened species. Active adaptive management provides a framework for valuing learning by measuring the degree to which it improves long-run management outcomes. The challenge of an active adaptive approach is to find the correct balance between gaining knowledge to improve management in the future and achieving the best short-term outcome based on current knowledge. We develop and analyze a framework for active adaptive management of a threatened species. Our case study concerns a novel facial tumor disease affecting the Australian threatened species Sarcophilus harrisii: the Tasmanian devil. We use stochastic dynamic programming with Bayesian updating to identify the management strategy that maximizes the Tasmanian devil population growth rate, taking into account improvements to management through learning to better understand disease latency and the relative effectiveness of three competing management options. Exactly which management action we choose each year is driven by the credibility of competing hypotheses about disease latency and by the population growth rate predicted by each hypothesis under the competing management actions. We discover that the optimal combination of management actions depends on the number of sites available and the time remaining to implement management. Our approach to active adaptive management provides a framework to identify the optimal amount of effort to invest in learning to achieve long-run conservation objectives

Pumping liquid manure from swine lagoons and holding ponds

1 online resource (PDF, 6 pages)This archival publication may not reflect current scientific knowledge or recommendations. Current information available from the University of Minnesota Extension: https://www.extension.umn.edu