Barbiturates

During the last decade, a new group of drugs, known as the barbiturates, has come into prominence in veterinary medicine as hypnotics and anesthetics. Today we find that these derivatives of barbituric acid are used quite extensively in human medicine and in the small animal field of veterinary medicine. The therapeutic action of the derivatives of this parent barbituric acid molecule, which is weakly acid but has no sedative or hypnotic effect, has been made possible because one or both of the hydrogens on the side chains are replaceable. Thus, barbital or diethyl barbituric acid was obtained by replacing each hydrogen with an ethyl radical, forming a derivative which did possess hypnotic and sedative action

Sterility In The Bull

Sterility is a pathological condition which has been more concisely termed the reduction or absence of fertility. Previously considered by members of the veterinary profession as being a rare occurrence, the problem is now receiving its due share of emphasis as a frequent affection of United States cattle herd sires. The development of artificial insemination with a more intensified form of cattle production in the last decade has brought this condition to the attention of the veterinarian. Formerly, it has been the policy of the farmer to simply discard, or sacrifice for meat, any bull which did not seem to be getting a proper conception rate. Rarely did the owner keep any breeding records to serve as an aid to the practitioner in the diagnosis and treatment of sterility

Schools and their communities: pupil and teacher perceptions of community action

In England over the last two decades, there has been a growing interest in the role of English schools in developing, facilitating and supporting young people’s community participation. A number of policy initiatives have sought to build the capacity and opportunities for youth participation. Research suggests, however, that pupils and schools are often prohibited by significant barriers from becoming involved with community activities, particularly those which might occur beyond the school environment itself. In March 2010 the UK Labour government launched a Youth Community Action initiative for England, piloted across five local authorities, which aimed to involve young people of 14-16 years-of-age in community action. Following the UK general election in May 2010, the Conservative-Liberal Democrat coalition government terminated these pilots but was quick to announce the launch and piloting of a National Citizen Service for 16-19 year olds in England. Purpose Drawing on research conducted with participants in one Youth Community Action pilot project, the aim of this study was to explore the perceptions and understandings of young people regarding their involvement in community action activities and how this compared to the perceptions and understandings of the teachers responsible for co-ordinating such activities. Sample In the final synthesis, the sample comprised 614 pupil questionnaires, representing a response rate of 24 percent of the pupils in the 9 participating schools. 11 semi-structured interviews and one focus group interview were conducted with pupils in 6 of the schools, with a further 8 semi-structured interviews conducted with teachers in these 6 schools. Design and methods A questionnaire was administered to pupils participating in the Youth Community Action pilot, enabling an exploration of self-reported behavioural attitudes and perceptions. The data collected was analysed thematically, with an identification of common themes in responses. In addition, factor analysis and a series of Chi² tests of association were carried out. The use of semi-structured interviews, the data from which were analysed thematically, enabled a qualitative exploration of pupils’ and teachers’ self-reported perceptions of community action activities. Results The findings of our questionnaires report that those pupils who know more about their local neighbourhood and community are likely to report greater levels of concern for what happens within it. This suggests that pupils’ learning about their neighbourhoods and community is likely to be beneficial toward developing affective attachments to them. For the pupils in our data-set, simply possessing pro-social behaviours and attitudes was not a sufficient or necessary condition for their community awareness and involvement. It suggests that, at least for a notable number of pupils, active engagement in the community requires cultivation and learning beyond pro-social behaviours. The semi-structured interviews report that pupils identify the school as the key source of information about community engagement opportunities, but also indicate that there is a marked difference in the activities which teachers identify their pupils as having undertaken, and the ability of pupils to vocalise these themselves. A further notable finding was a focus on the practical (time, distance, age-constraints) and social (peer-pressure) barriers to community action activities to the exclusion of specifically educational (lack of understanding and skills) barriers. Conclusions Results from this study suggest that schools represent an important source for pupils’ community involvement, but that in our sample pupils often lack the vocabulary with which to explain the extent and nature of such engagement. Pupils and teachers identify a range of barriers to and benefits of community involvement, but these do not include a lack of understanding or skills. The research raises important questions in the context of recent policy trends in England

Methods of fitting multivariant functional models in the area of large computer exploita- tion final report, 23 may 1963 - 23 jul. 1965

Methods of fitting multivariant functional models in area of large computer exploitatio

Neighbour transitivity on codes in Hamming graphs

We consider a \emph{code} to be a subset of the vertex set of a \emph{Hamming graph}. In this setting a \emph{neighbour} of the code is a vertex which differs in exactly one entry from some codeword. This paper examines codes with the property that some group of automorphisms acts transitively on the \emph{set of neighbours} of the code. We call these codes \emph{neighbour transitive}. We obtain sufficient conditions for a neighbour transitive group to fix the code setwise. Moreover, we construct an infinite family of neighbour transitive codes, with \emph{minimum distance} $\delta=4$, where this is not the case. That is to say, knowledge of even the complete set of code neighbours does not determine the code

Reverberation Mapping and the Physics of Active Galactic Nuclei

Reverberation-mapping campaigns have revolutionized our understanding of AGN. They have allowed the direct determination of the broad-line region size, enabled mapping of the gas distribution around the central black hole, and are starting to resolve the continuum source structure. This review describes the recent and successful campaigns of the International AGN Watch consortium, outlines the theoretical background of reverberation mapping and the calculation of transfer functions, and addresses the fundamental difficulties of such experiments. It shows that such large-scale experiments have resulted in a ``new BLR'' which is considerably different from the one we knew just ten years ago. We discuss in some detail the more important new results, including the luminosity-size-mass relationship for AGN, and suggest ways to proceed in the near future.Comment: Review article to appear in Astronomical Time Series, Proceedings of the Wise Observatory 25th Ann. Symposium. 24 pages including 7 figure

Chiral and herringbone symmetry breaking in water-surface monolayers

We report the observation from monolayers of eicosanoic acid in the L′2 phase of three distinct out-of-plane first-order diffraction peaks, indicating molecular tilt in a nonsymmetry direction and hence the absence of mirror symmetry. At lower pressures the molecules tilt in the direction of their nearest neighbors. In this region we find a structural transition, which we tentatively identify as the rotator-herringbone transition L2d−L2h