Some factors influencing success of IVF-embryo transfer

Assisted reproduction is a field of medicine that deals with infertility tretment. Ongoing improvements of laboratory technology as well as ongoing evolving scientific research within IVF research,including experimental embryology in routine practice is contributing in a steady improvement of success rates of assisted reproduction. This thesis is primarily based on data and information provided by the laboratory of assisted reproduction of GEST IVF Ltd.clinic in Prague,which was collected during the year 2015. This data was analyzed and investigated to verify the effect of selected factors on the success of the treatment. In This thesis we have not used any personal data of patients in accordance with the legislation act.296/2008Sb. The results show clear evidence between the treatment success rate and patients age within all evaluated parameters. The fundametal hypothesis of interdependence of embryo quality on the further development of the embryo after the transfer was comfirmed. Conversely, the timeframe for embryo cultivation is not an important parameter of success. Commonly used cuture media also did not show a significant impact on treatment outcome. Statistical calculations also confirmed surprisingly significant differences in embryo transfer after 72 hours development and 120 hours development for women ever 35 years. Transfers of younger embryos appears to be more convenient for women over 35 years

Geology, U-Pb dating and 3D visualisation of late-orogenic Klenov Pluton (Pelhřimov Core Complex, Central European Variscides)

ABSTRACTThe geological map of the Klenov Pluton (Moldanubian Batholith), and its 3D visualization, brings the new findings in the context of granite emplacement within late-Variscan settings. The Klenov Pluton has a peraluminous composition resulting from partial melting of metasedimentary sources and subsequent differentiation. The new ages 327.14 ± 0.21 Ma and 327.80 ± 0.37 Ma, reflect the narrow time-span of magma emplacement and cooling. The 327 Ma Klenov Pluton was emplaced syntectonically as a ‘sheet-like’ granite intrusion at depth ca. 10 kilometers during the later stages of the Pelhřimov Core Complex exhumation (at ca. 329 to 327 Ma) associated with ∼N–S oriented compression. Gravity modelling suggests that the Klenov Pluton has an asymmetric shape where its western flank is parallel to the ∼NW moderately dipping Pelhřimov Core Complex. The eastern margin of the Pluton is shallower and has been later modified by ∼SE-side-up normal faulting (Lodhéřov Fault Zone)

Geology, U-Pb dating and 3D visualisation of late-orogenic Klenov Pluton (Pelhřimov Core Complex, Central European Variscides)

The geological map of the Klenov Pluton (Moldanubian Batholith), and its 3D visualization, brings the new findings in the context of granite emplacement within late-Variscan settings. The Klenov Pluton has a peraluminous composition resulting from partial melting of metasedimentary sources and subsequent differentiation. The new ages 327.14 ± 0.21 Ma and 327.80 ± 0.37 Ma, reflect the narrow time-span of magma emplacement and cooling. The 327 Ma Klenov Pluton was emplaced syntectonically as a ‘sheet-like’ granite intrusion at depth ca. 10 kilometers during the later stages of the Pelhřimov Core Complex exhumation (at ca. 329 to 327 Ma) associated with ∼N–S oriented compression. Gravity modelling suggests that the Klenov Pluton has an asymmetric shape where its western flank is parallel to the ∼NW moderately dipping Pelhřimov Core Complex. The eastern margin of the Pluton is shallower and has been later modified by ∼SE-side-up normal faulting (Lodhéřov Fault Zone).</p