24,810 research outputs found

    Maternal haemodynamic function differs in pre‐eclampsia when it is associated with a small‐for‐gestational‐age newborn: a prospective cohort study

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    Objective To describe maternal haemodynamic differences in gestational hypertension with small‐for‐gestational‐age babies (HDP + SGA), gestational hypertension with appropriate‐for‐gestational‐age babies (HDP‐only) and control pregnancies. Design Prospective cohort study. Setting Tertiary Hospital, UK. Population Women with gestational hypertension and healthy pregnant women. Methods Maternal haemodynamic indices were measured using a non‐invasive Ultrasound Cardiac Output Monitor (USCOM‐1A¼) and corrected for gestational age and maternal characteristics using device‐specific reference ranges. Main outcome measures Maternal cardiac output, stroke volume, systemic vascular resistance. Results We included 114 HDP + SGA, 202 HDP‐only and 401 control pregnancies at 26–41 weeks of gestation. There was no significant difference in the mean arterial blood pressure (110 versus 107 mmHg, P = 0.445) between the two HDP groups at presentation. Pregnancies complicated by HDP + SGA had significantly lower median heart rate (76 versus 85 bpm versus 83 bpm), lower cardiac output (0.85 versus 0.98 versus 0.97 MoM) and higher systemic vascular resistance (1.4 versus 1.0 versus 1.2 MoM) compared with control and HDP‐only pregnancies, respectively (all P < 0.05). Conclusion Women with HDP + SGA present with more severe haemodynamic dysfunction than HDP‐only. Even HDP‐only pregnancies exhibit impaired haemodynamic indices compared with normal pregnancies, supporting a role of the maternal cardiovascular system in gestational hypertension irrespective of fetal size. Central haemodynamic changes may play a role in the pathogenesis of pre‐eclampsia and should be considered alongside placental aetiology

    Performance of blasting caps

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    Common blasting caps are made from an aluminum shell in the form of a tube which is closed at both ends. One end, which is called the output end, terminates in a principal side or face, and contains a detonating agent which communicates with a means for igniting the detonating agent. The improvement of the present invention is a flat, steel foil bonded to the face in a position which is aligned perpendicularly to the longitudinal axis of the tube

    Comparison of analytical and wind-tunnel results for flutter and gust response of a transport wing with active controls

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    Two flutter suppression control laws wre designed and tested on a low speed aeroelastic model of a DC-10 derivative wing. Both control laws demontrated increases in flutter speed in excess of 25 percent above the passive wing flutter speed. In addition, one of the control laws was effective in reducing loads due to turbulence generated in the wind tunnel. The effect of variations in gain and phase on the closed-loop performance was measured and is compared with predictions. In general, both flutter and gust response predictions agree reasonably well with experimental data

    HABITAT UTILIZATION BY THE TEXAS HORNED LIZARD (PHRYNOSOMA CORNUTUM) FROM TWO SITES IN CENTRAL TEXAS

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    The Texas Horned Lizard (Phrynosoma cornutum) is found in a variety of habitats. Although several studies have been conducted on habitat use by this species, none have been performed in central Texas, a more mesic habitat than most of those previously studied. This area is of special interest because horned lizard populations have been experiencing sharp declines in central Texas over the last approximately 50 years. We collected habitat data at two sites in central Texas, Camp Bowie and Blue Mountain Peak Ranch. Microhabitat data included canopy cover and ground cover from digitized photographs of Daubenmire quadrats; macrohabitat variables included vegetation height and length, cactus height, soil penetrability, woody plant species richness, tree density, tree diameter at breast height (DBH), and density of ant mounds collected along 100-m by 2-m transects. Similar patterns of habitat use were observed between the two sites. At Blue Mountain Peak Ranch, lizards appeared to be located in areas with a diversity of ground cover types, as observed in previous studies. At Camp Bowie, vegetation encroachment limited lizards in some areas to the use of roads and road margins. Implementation of prescribed burns or other vegetation management could create the preferred ground cover mosaic at such sites

    Differences in the epidemiology of theileriosis on smallholder dairy farms in contrasting agro-ecological and grazing strata of highland Kenya

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    A prospective cohort study was conducted in five purposively-sampled agro-ecological zone (AEZ)-grazing system strata in Murang’a District, Kenya, between March 1995 and June 1996. The study strata were selected based on a preliminary characterization study to represent the widest range of risks to East Coast fever (ECF) in the District and included zero-grazing and open-grazing farms. In total, 225 calves from 188 smallholder farms were examined from birth to 6 months of age and visited within the first 2 weeks of life and thereafter at bi-weekly intervals for up to 14 visits. The purpose of the study was to characterize the differences in epidemiology (risks of infection, morbidity and mortality) and potential control of ECF between the selected strata. Evidence of Theileria parva infection was assessed by increased antibody levels as measured in an indirect ELISA assay by the percent positivity (PP) of serum samples relative to a strong positive reference serum. Sero-conversion risks of T. parva were highest in the open-grazing strata. Antibody prevalence in adult cattle and ECF morbidity and mortality risks were also highest in open-grazing strata. While different, all five AEZ-grazing strata were considered to be endemically unstable for ECF. East Coast fever challenge was low in all zero-grazing strata and this challenge is likely to remain low due to continuing intensification of smallholder farming in the central highlands. In the open-grazing strata, there was higher challenge and a greater impact of ECF. ILRI publication no.: 99017

    Analytic Treatment of Positronium Spin Splittings in Light-Front QED

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    We study the QED bound-state problem in a light-front hamiltonian approach. Starting with a bare cutoff QED Hamiltonian, HBH_{_{B}}, with matrix elements between free states of drastically different energies removed, we perform a similarity transformation that removes the matrix elements between free states with energy differences between the bare cutoff, Λ\Lambda, and effective cutoff, \lam (\lam < \Lam). This generates effective interactions in the renormalized Hamiltonian, HRH_{_{R}}. These effective interactions are derived to order α\alpha in this work, with αâ‰Ș1\alpha \ll 1. HRH_{_{R}} is renormalized by requiring it to satisfy coupling coherence. A nonrelativistic limit of the theory is taken, and the resulting Hamiltonian is studied using bound-state perturbation theory (BSPT). The effective cutoff, \lam^2, is fixed, and the limit, 0 \longleftarrow m^2 \alpha^2\ll \lam^2 \ll m^2 \alpha \longrightarrow \infty, is taken. This upper bound on \lam^2 places the effects of low-energy (energy transfer below \lam) emission in the effective interactions in the ∣ee‟>| e {\overline e} > sector. This lower bound on \lam^2 insures that the nonperturbative scale of interest is not removed by the similarity transformation. As an explicit example of the general formalism introduced, we show that the Hamiltonian renormalized to O(α)O(\alpha) reproduces the exact spectrum of spin splittings, with degeneracies dictated by rotational symmetry, for the ground state through O(α4)O(\alpha^4). The entire calculation is performed analytically, and gives the well known singlet-triplet ground state spin splitting of positronium, 7/6α2Ryd7/6 \alpha^2 Ryd. We discuss remaining corrections other than the spin splittings and how they can be treated in calculating the spectrum with higher precision.Comment: 46 pages, latex, 3 Postscript figures included, section on remaining corrections added, title changed, error in older version corrected, cutoff placed in a windo
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