418 research outputs found

    AN ASSESSMENT OF MUNICIPAL WATER RIGHTS AND WATER SYSTEMS IN THE CLARK FORK RIVER BASIN

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    In the semi-arid Inland Northwest, water is undoubtedly the most important natural resource. Western Montana’s Clark Fork River basin is no exception. As the population of western Montana continues to grow, the Clark Fork River basin below the Flathead Indian Reservation is largely in de facto closure to the establishment of new water rights. Communities face a great amount of uncertainty with respect to their ability to establish new water rights to accommodate future growth due to the de facto closure, along with the ongoing adjudication process and the inability for communities to grow into their claimed water rights established before July 1, 1973. It is therefore essential for communities, and water resources planners and managers, to know their legal and physical entitlements to water. This assessment of municipal water rights and systems in the Clark Fork River basin was conducted by ascertaining the volumes and maximum flows of each community’s water right, analyzing the volume of water used annually, and projecting future water consumption amounts for the next 20 years based on projected county population growth rates. Other information gathered includes water conservation measures, water-related infrastructure, and metering. Interviews of water system managers and operators were conducted to gauge their level of understanding of water resource issues and policies that might play a significant role in each community’s ability to provide water to its residents. It appears that while the vast majority of communities in the Clark Fork River basin will have sufficient water right amounts for the next 20 years, other communities, e.g., Seeley Lake, Hamilton, and Missoula are more likely to experience difficulties in meeting future population growth with their current rights. Some communities, e.g., Butte, Columbia Falls, Superior, and Thompson Falls, may be limited in using their water rights due to water quality issues, while others, e.g., Hamilton, Missoula, and Stevensville, will be limited due to the Montana Department of Natural Resources and Conservation’s rules regarding where water rights are able to be used

    Psychology, History, and Social Justice: Concluding Reflections

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111999/1/josi12118.pd

    Congenital Viral Infections of the Brain: Lessons Learned from Lymphocytic Choriomeningitis Virus in the Neonatal Rat

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    The fetal brain is highly vulnerable to teratogens, including many infectious agents. As a consequence of prenatal infection, many children suffer severe and permanent brain injury and dysfunction. Because most animal models of congenital brain infection do not strongly mirror human disease, the models are highly limited in their abilities to shed light on the pathogenesis of these diseases. The animal model for congenital lymphocytic choriomeningitis virus (LCMV) infection, however, does not suffer from this limitation. LCMV is a well-known human pathogen. When the infection occurs during pregnancy, the virus can infect the fetus, and the developing brain is particularly vulnerable. Children with congenital LCMV infection often have substantial neurological deficits. The neonatal rat inoculated with LCMV is a superb model system of human congenital LCMV infection. Virtually all of the neuropathologic changes observed in humans congenitally infected with LCMV, including microencephaly, encephalomalacia, chorioretinitis, porencephalic cysts, neuronal migration disturbances, periventricular infection, and cerebellar hypoplasia, are reproduced in the rat model. Within the developing rat brain, LCMV selectively targets mitotically active neuronal precursors. Thus, the targets of infection and sites of pathology depend on host age at the time of infection. The rat model has further shown that the pathogenic changes induced by LCMV infection are both virus-mediated and immune-mediated. Furthermore, different brain regions simultaneously infected with LCMV can undergo widely different pathologic changes, reflecting different brain region–virus–immune system interactions. Because the neonatal rat inoculated with LCMV so faithfully reproduces the diverse neuropathology observed in the human counterpart, the rat model system is a highly valuable tool for the study of congenital LCMV infection and of all prenatal brain infections In addition, because LCMV induces delayed-onset neuronal loss after the virus has been cleared, the neonatal rat infected with LCMV may be an excellent model system to study neurodegenerative or psychiatric diseases whose etiologies are hypothesized to be virus-induced, such as autism, schizophrenia, and temporal lobe epilepsy

    CHANG-ES V: Nuclear Radio Outflow in a Virgo Cluster Spiral after a Tidal Disruption Event

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    We have observed the Virgo Cluster spiral galaxy, NGC~4845, at 1.6 and 6 GHz using the Karl G. Jansky Very Large Array, as part of the `Continuum Halos in Nearby Galaxies -- an EVLA Survey' (CHANG-ES). The source consists of a bright unresolved core with a surrounding weak central disk (1.8 kpc diameter). The core is variable over the 6 month time scale of the CHANG-ES data and has increased by a factor of \approx 6 since 1995. The wide bandwidths of CHANG-ES have allowed us to determine the spectral evolution of this core which peaks {\it between} 1.6 and 6 GHz (it is a GigaHertz-peaked spectrum source).We show that the spectral turnover is dominated by synchrotron self-absorption and that the spectral evolution can be explained by adiabatic expansion (outflow), likely in the form of a jet or cone. The CHANG-ES observations serendipitously overlap in time with the hard X-ray light curve obtained by Nikolajuk \& Walter (2013) which they interpret as due to a tidal disruption event (TDE) of a super-Jupiter mass object around a 105M10^5\, M_\odot black hole. We outline a standard jet model, provide an explanation for the observed circular polarization, and quantitatively suggest a link between the peak radio and peak X-ray emission via inverse Compton upscattering of the photons emitted by the relativistic electrons. We predict that it should be possible to resolve a young radio jet via VLBI as a result of this nearby TDE.Comment: 45 pages, 10 figures, accepted July 2, 2015 to the Astrophysical Journa

    Peripheral blood gene expression reveals an inflammatory transcriptomic signature in Friedreich's ataxia patients.

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    Transcriptional changes in Friedreich's ataxia (FRDA), a rare and debilitating recessive Mendelian neurodegenerative disorder, have been studied in affected but inaccessible tissues-such as dorsal root ganglia, sensory neurons and cerebellum-in animal models or small patient series. However, transcriptional changes induced by FRDA in peripheral blood, a readily accessible tissue, have not been characterized in a large sample. We used differential expression, association with disability stage, network analysis and enrichment analysis to characterize the peripheral blood transcriptome and identify genes that were differentially expressed in FRDA patients (n = 418) compared with both heterozygous expansion carriers (n = 228) and controls (n = 93 739 individuals in total), or were associated with disease progression, resulting in a disease signature for FRDA. We identified a transcriptional signature strongly enriched for an inflammatory innate immune response. Future studies should seek to further characterize the role of peripheral inflammation in FRDA pathology and determine its relevance to overall disease progression

    A survey of X-ray emission from 100 kpc radio jets

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    We have completed a Chandra snapshot survey of 54 radio jets that are extended on arcsec scales. These are associated with flat spectrum radio quasars spanning a redshift range z=0.3 to 2.1. X-ray emission is detected from the jet of approximately 60% of the sample objects. We assume minimum energy and apply conditions consistent with the original Felten-Morrison calculations in order to estimate the Lorentz factors and the apparent Doppler factors. This allows estimates of the enthalpy fluxes, which turn out to be comparable to the radiative luminosities.Comment: Conference Proceedings IAU Symposium No. 313, Extragalactic jets from every angle, pp. 219-224, 4 figure

    Review of Consequential Strangers: The Power of People Who Don't Seem to Matter … But Really Do

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    A review of Consequential Strangers: The Power of People Who Don't Seem to Matter … But Really Do. Melinda Blau and Karen L. Fingerman. New York: Norton. 2009

    Heterosexual romantic relationships, interpersonal needs, and quality of life in prison.

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    The purpose of this study was to investigate the moderating effect of having vs. not having a heterosexual romantic partner inside the prison on the relationship between interpersonal needs and quality of life. In-person interviews were conducted with 55 male and 64 female inmates from the Topas Penitentiary (Spain). Higher levels of social loneliness and lower levels of sexual satisfaction were associated with lower levels of quality of life. In addition, the interaction between sexual satisfaction and romantic partner status was significant. Higher levels of sexual satisfaction were associated with higher levels of quality of life only for the group without a partner. These findings support a “bad is stronger than good” principle and indicate the detrimental aspects that can be associated with not having a satisfactory sexual life while incarcerated

    The Best of Times, the Worst of Times: The Place of Close Relationships in Psychology and Our Daily Lives

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    This article examines the place of relationships in our daily lives and in the field of psychology. The first section of the article offers reasons why relationships are central for humans. Next, the place of relationships in the history, institutional aspects, and subfields of psychology is presented. Then a paradox about relationships is presented: They are both among the most positive, uplifting of life's experiences and yet they can also be among life's darkest aspects. Despite the negative aspects of relationships, most people are very happy in their intimate relations. The paper ends with possible explanations for why satisfaction may be so high
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