3-烷基，3-二氢-1H-异吲哚-1-酮的不对称合成

3-烷基-2，3-二氢-1H-异吲哚-1-酮(I)类化合物存在于许多天然有机物和生理活性物质的核心结构中,具有广阔的医学和生化应用前景。此外,这类化合物还可作为不对称合成的手性辅助剂,还原后可作为手性配体,在不对称合成中具有潜在的应用前景。本论文的目的是在本实验室以往研究工作的基础上，开发手性异吲哚酮合成子的合成路线，建立一种灵活多用的合成方法，以期为不对称合成提供新型手性辅助剂,用于不对称合成反应。首先，从邻苯二甲酸酐(II)和（R）-（-）-苯基甘氨醇(III)出发,合成了N–取代邻苯二甲酰亚胺(V)。把V的羟基用苄基保护后的产物VI进行还原烷基化反应,即格氏试剂加成—三氟化硼合乙醚催化下...The 3-substituted-2,3-dihydro-1H-isoindol-1-ones (I) are found as core units in many natural and/or bioactive compounds, they have broad prospect in fields of medicine and biochemistry. After amide carbonyl reduction, they can serve as a group of promising chiral auxiliaries in asymmetric synthesis. Our laboratory has developed a general method for the asymmetric synthesis of pyrrolidines, 2-pyrro...学位：理学硕士院系专业：化学化工学院化学系_有机化学学号：19972501

The International Linear Collider: Report to Snowmass 2021

The International Linear Collider (ILC) is on the table now as a new global energy-frontier accelerator laboratory taking data in the 2030s. The ILC addresses key questions for our current understanding of particle physics. It is based on a proven accelerator technology. Its experiments will challenge the Standard Model of particle physics and will provide a new window to look beyond it. This document brings the story of the ILC up to date, emphasizing its strong physics motivation, its readiness for construction, and the opportunity it presents to the US and the global particle physics community

The International Linear Collider: Report to Snowmass 2021

The International Linear Collider (ILC) is on the table now as a new global energy-frontier accelerator laboratory taking data in the 2030s. The ILC addresses key questions for our current understanding of particle physics. It is based on a proven accelerator technology. Its experiments will challenge the Standard Model of particle physics and will provide a new window to look beyond it. This document brings the story of the ILC up to date, emphasizing its strong physics motivation, its readiness for construction, and the opportunity it presents to the US and the global particle physics community

The International Linear Collider: Report to Snowmass 2021

International audienceThe International Linear Collider (ILC) is on the table now as a new global energy-frontier accelerator laboratory taking data in the 2030s. The ILC addresses key questions for our current understanding of particle physics. It is based on a proven accelerator technology. Its experiments will challenge the Standard Model of particle physics and will provide a new window to look beyond it. This document brings the story of the ILC up to date, emphasizing its strong physics motivation, its readiness for construction, and the opportunity it presents to the US and the global particle physics community

The International Linear Collider: Report to Snowmass 2021

International audienceThe International Linear Collider (ILC) is on the table now as a new global energy-frontier accelerator laboratory taking data in the 2030s. The ILC addresses key questions for our current understanding of particle physics. It is based on a proven accelerator technology. Its experiments will challenge the Standard Model of particle physics and will provide a new window to look beyond it. This document brings the story of the ILC up to date, emphasizing its strong physics motivation, its readiness for construction, and the opportunity it presents to the US and the global particle physics community