40,190 research outputs found
Gonadal hormones, but not sex, affect the acquisition and maintenance of a Go/No-Go odor discrimination task in mice
In mice, olfaction is crucial for identifying social odors (pheromones) that signal the presence of suitable mates. We used a custom-built olfactometer and a thirst-motivated olfactory discrimination Go/No-Go (GNG) task to ask whether discrimination of volatile odors is sexually dimorphic and modulated in mice by adult sex hormones. Males and females gonadectomized prior to training failed to learn even the initial phase of the task, which involved nose poking at a port in one location obtaining water at an adjacent port. Gonadally intact males and females readily learned to seek water when male urine (S+) was present but not when female urine (Sâ) was present; they also learned the task when non-social odorants (amyl acetate, S+; peppermint, Sâ) were used. When mice were gonadectomized after training the ability of both sexes to discriminate urinary as well as non-social odors was reduced; however, after receiving testosterone propionate (castrated males) or estradiol benzoate (ovariectomized females), task performance was restored to pre-gonadectomy levels. There were no overall sex differences in performance across gonadal conditions in tests with either set of odors; however, ovariectomized females performed more poorly than castrated males in tests with non-social odors. Our results show that circulating sex hormones enable mice of both sexes to learn a GNG task and that gonadectomy reduces, while hormone replacement restores, their ability to discriminate between odors irrespective of the saliency of the odors used. Thus, gonadal hormones were essential for both learning and maintenance of task performance across sex and odor type.We thank David Giese for help in programming the apparatus used in GNG testing and Alberto Cruz-Martin for comments on an early version of the manuscript. This work was supported by NIDCD grant DC008962 to JAC. (DC008962 - NIDCD grant)Accepted manuscrip
Incomplete quantum process tomography and principle of maximal entropy
The main goal of this paper is to extend and apply the principle of maximum
entropy (MaxEnt) to incomplete quantum process estimation tasks. We will define
a so-called process entropy function being the von Neumann entropy of the state
associated with the quantum process via Choi-Jamiolkowski isomorphism. It will
be shown that an arbitrary process estimation experiment can be reformulated in
a unified framework and MaxEnt principle can be consistently exploited. We will
argue that the suggested choice for the process entropy satisfies natural list
of properties and it reduces to the state MaxEnt principle, if applied to
preparator devices.Comment: 8 pages, comments welcome, references adde
Three dimensional loop quantum gravity: physical scalar product and spin foam models
In this paper, we address the problem of the dynamics in three dimensional
loop quantum gravity with zero cosmological constant. We construct a rigorous
definition of Rovelli's generalized projection operator from the kinematical
Hilbert space--corresponding to the quantization of the infinite dimensional
kinematical configuration space of the theory--to the physical Hilbert space.
In particular, we provide the definition of the physical scalar product which
can be represented in terms of a sum over (finite) spin-foam amplitudes.
Therefore, we establish a clear-cut connection between the canonical
quantization of three dimensional gravity and spin-foam models. We emphasize
two main properties of the result: first that no cut-off in the kinematical
degrees of freedom of the theory is introduced (in contrast to standard
`lattice' methods), and second that no ill-defined sum over spins (`bubble'
divergences) are present in the spin foam representation.Comment: Typos corrected, version appearing in Class. Quant. Gra
Using automatic robot programming for space telerobotics
The interpreter of a task level robot programming system called Handey is described. Handey is a system that can recognize, manipulate and assemble polyhedral parts when given only a specification of the goal. To perform an assembly, Handey makes use of a recognition module, a gross motion planner, a grasp planner, a local approach planner and is capable of planning part re-orientation. The possibility of including these modules in a telerobotics work-station is discussed
Modeling Variable Emission Lines in AGNs: Method and Application to NGC 5548
We present a new scheme for modeling the broad line region in active galactic
nuclei (AGNs). It involves photoionization calculations of a large number of
clouds, in several pre-determined geometries, and a comparison of the
calculated line intensities with observed emission line light curves. Fitting
several observed light curves simultaneously provides strong constraints on
model parameters such as the run of density and column density across the
nucleus, the shape of the ionizing continuum, and the radial distribution of
the emission line clouds. When applying the model to the Seyfert 1 galaxy NGC
5548, we were able to reconstruct the light curves of four ultraviolet
emission-lines, in time and in absolute flux. This has not been achieved by any
previous work. We argue that the Balmer lines light curves, and possibly also
the MgII2798 light curve, cannot be tested in this scheme because of the
limitations of present-day photoionization codes. Our fit procedure can be used
to rule out models where the particle density scales as r^{-2}, where r is the
distance from the central source. The best models are those where the density
scales as r^{-1} or r^{-1.5}. We can place a lower limit on the column density
at a distance of 1 ld, of N_{col}(r=1) >~ 10^{23} cm^{-2} and limit the
particle density to be in the range of 10^{12.5}>N(r=1)>10^{11} cm^{-3}. We
have also tested the idea that the spectral energy distribution (SED) of the
ionizing continuum is changing with continuum luminosity. None of the
variable-shape SED tried resulted in real improvement over a constant SED case
although models with harder continuum during phases of higher luminosity seem
to fit better the observed spectrum. Reddening and/or different composition
seem to play a minor role, at least to the extent tested in this work.Comment: 12 pages, including 9 embedded EPS figures, accepted for publication
in Ap
Modelling fungal colonies and communities:challenges and opportunities
This contribution, based on a Special Interest Group session held during IMC9, focuses on physiological based models of filamentous fungal colony growth and interactions. Fungi are known to be an important component of ecosystems, in terms of colony dynamics and interactions within and between trophic levels. We outline some of the essential components necessary to develop a fungal ecology: a mechanistic model of fungal colony growth and interactions, where observed behaviour can be linked to underlying function; a model of how fungi can cooperate at larger scales; and novel techniques for both exploring quantitatively the scales at which fungi operate; and addressing the computational challenges arising from this highly detailed quantification. We also propose a novel application area for fungi which may provide alternate routes for supporting scientific study of colony behaviour. This synthesis offers new potential to explore fungal community dynamics and the impact on ecosystem functioning
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