15,205 research outputs found
Quantum States Allowing Minimum Uncertainty Product of angular position and momentum
We provide necessary and sufficient conditions for states to have an
arbitrarily small uncertainty product of the azimuthal angle and its
canonical moment . We illustrate our results with analytical examples
A Prospective Analysis of Adverse Drug Reactions in a South Indian Hospital
Adverse drug reactions are a great cause of concern to the medical profession, the patients and the pharmaceutical industry. However ADR reporting and monitoring is yet to catch up in India. Hence we undertook a study to record and analyze adverse reactions among all patients admitted to the medical wards of a tertiary care. Centre patients admitted to all medical wards over one year were assessed for ADRs throughout their admission. Suspected ADRs were recorded and analyzed for i) the type of reaction ii) severity iii) Consequence on treatment that is if the drug was continued, or stopped, or needed to be treated with other drugs, iv) Physiological system involved and the v) group of the drugs associated with ADRs. Among 1250 patients admitted during the study period, 250 adverse events were observed. Majority (76.8%) were of mild type, 66% were severe requiring intensive care and 3 patients died. Antimicrobials were responsible for maximum (42.4%) ADRs followed by drugs acting on CNS (20%). When we analyzed the systems affected, CNS side effects were more common in our study. While in many other studies Cardiovascular and gastrointestinal side effects were the most common. Combination of drugs was responsible for a large percentage of ADRs. Inadvertent use of antipsychotics with sedatives led to respiratory failure in 4 patients of which 1 died. Contaminated IV fluids are suspected to be the cause of death in another fatal ADR. In conclusion there is a need for vigilant ADR monitoring to be done by all doctors to prevent morbidity and mortality from ADRs
Knowledge of Pharmacology of Analgesics Among Nurses in a Tertiary Centre
Objectives: To evaluate the knowledge of nurses about the analgesics they administer in our hospital. Methodology: A total of 102 nurses completed the questionnaire which included 20 multiple choice questions based on the dosage forms, mechanism of action, route of administration, adverse effects of the commonly administered analgesics, the nurses’ educational qualifications and their working experience. Frequency, percentage, mean, Kruskal Wallis test and Mann Whitneys test were used to analyse data. Answers were given a score out of 20(100%). Results: The sample comprised of 17(16.6%) senior staff nurses, 38(37%) junior staff nurses and 47(46%) student nurses. Of the staff, 10.8 % were BSc and MSc nurses, 43.1 were GNM staff. The mean knowledge score of BSc & MSc staff was 12.18, GNM staff was 11.7 and of student nurses was 13.38. None of the groups scored more than 15, suggesting their knowledge was inadequate. There was a correlation between knowledge and experience in the staff nurses. Conclusion: The result of this study suggests that the knowledge of pharmacology of analgesics among nurses is inadequate, and thus supports the need for supplementary pharmacology education for nurses in clinical settings, focusing on common drugs they administer and help prevent medical errors
Orthogonality catastrophe and Kondo effect in graphene
Anderson's orthogonality catastrophe in graphene, at energies close to the
Dirac point, is analyzed. It is shown that, in clean systems, the orthogonality
catastrophe is suppressed, due to the vanishing density of states at the Dirac
point. In the presence of preexisting localized states at the Dirac energy, the
orthogonality catastrophe shows similar features to those found in normal
metals with a finite density of states at the Fermi level. The implications for
the Kondo effect induced by magnetic impurities, and for the Fermi edge
singularities in tunneling processes are also discussed.Comment: 7 pages, 7 figure
Connectivity-Driven Coherence in Complex Networks
We study the emergence of coherence in complex networks of mutually coupled
non-identical elements. We uncover the precise dependence of the dynamical
coherence on the network connectivity, on the isolated dynamics of the elements
and the coupling function. These findings predict that in random graphs, the
enhancement of coherence is proportional to the mean degree. In locally
connected networks, coherence is no longer controlled by the mean degree, but
rather on how the mean degree scales with the network size. In these networks,
even when the coherence is absent, adding a fraction s of random connections
leads to an enhancement of coherence proportional to s. Our results provide a
way to control the emergent properties by the manipulation of the dynamics of
the elements and the network connectivity.Comment: 4 pages, 2 figure
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The association of neutrophil-lymphocyte ratio and lymphocyte-monocyte ratio with 3-month clinical outcome after mechanical thrombectomy following stroke
Background and aim
Neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR) are associated with clinical outcomes in malignancy, cardiovascular disease and stroke. Here we investigate their association with outcome after acute ischaemic stroke treated by mechanical thrombectomy (MT).
Methods
Patients were selected using audit data for MT for acute anterior circulation ischaemic stroke at a UK centre from May 2016–July 2017. Clinical and laboratory data including neutrophil, lymphocyte and monocyte count tested before and 24 h after MT were collected. Poor functional outcome was defined as modified Rankin Scale (mRS) of 3–6 at 3 months. Multivariable logistic regression analyses were performed to explore the relationship of NLR and LMR with functional outcome.
Results
One hundred twenty-one patients (mean age 66.4 ± 16.7, 52% female) were included. Higher NLR (adjusted OR 0.022, 95% CI, 0.009–0.34, p = 0.001) and lower LMR (adjusted OR − 0.093, 95% CI (− 0.175)−(− 0.012), p = 0.025) at 24-h post-MT were significantly associated with poorer functional outcome when controlling for age, baseline NIHSS score, infarct size, presence of good collateral supply, recanalisation and symptomatic intracranial haemorrhage on multivariate logistic regression. Admission NLR or LMR were not significant predictors of mRS at 3 months. The optimal cut-off values of NLR and LMR at 24-h post-MT that best discriminated poor outcome were 5.5 (80% sensitivity and 60% specificity) and 2.0 (80% sensitivity and 50% specificity), respectively on receiver operating characteristic curve analysis.
Conclusion
NLR and LMR tested at 24 h after ictus or intervention may predict 3-month functional outcome
NETCU: analising e-Learning neworked curricula in Europe: the importance of legal and quality assurance aspects
Conferência realizada no Porto de 6-9 de junho de 2012info:eu-repo/semantics/publishedVersio
Diluted manganese on the bond-centered site in germanium
The functional properties of Mn-doped Ge depend to large extent on the lattice location of the Mn impurities. Here, we present a lattice location study of implanted diluted Mn by means of electron emission channeling. Surprisingly, in addition to the expected substitutional lattice position, a large fraction of the Mn impurities occupies the bond-centered site. Corroborated by ab initio calculations, the bond-centered Mn is related to Mn-vacancy complexes. These unexpected results call for a reassessment of the theoretical studies on the electrical and magnetic behavior of Mn-doped Ge, hereby including the possible role of Mn-vacancy complexes
Alfvenic Heating of Protostellar Accretion Disks
We investigate the effects of heating generated by damping of Alfven waves on
protostellar accretion disks. Two mechanisms of damping are investigated,
nonlinear and turbulent, which were previously studied in stellar winds
(Jatenco-Pereira & Opher 1989a, b). For the nominal values studied, f=delta
v/v_{A}=0.002 and F=varpi/Omega_{i}=0.1, where delta v, v_{A} and varpi are the
amplitude, velocity and average frequency of the Alfven wave, respectively, and
Omega_{i} is the ion cyclotron frequency, we find that viscous heating is more
important than Alfven heating for small radii. When the radius is greater than
0.5 AU, Alfvenic heating is more important than viscous heating. Thus, even for
the relatively small value of f=0.002, Alfvenic heating can be an important
source of energy for ionizing protostellar disks, enabling angular momentum
transport to occur by the Balbus-Hawley instability.Comment: 21 pages, 9 figures. Accepted for publication in Ap
Innovativeness, innovation behavior and performance in the Portuguese hotel industry
This work investigates hotel innovation activity based on 11 hotel-specific innovation dimensions and antecedents. Results from a sample of 326 Portuguese hotels showed a high level of Innovativeness in the Portuguese hospitality industry. Information and Communication Technology, and Marketing were the leading innovation areas. The moderate level of Innovation Behavior demonstrates the dominance of incremental innovations. Hotel Size, Hotel Stars, Hotel
Chain, and Personnel Training are significantly related to Innovation Behavior. Hotel Innovativeness positively impacted hotel Innovation Behavior, and hotel Innovation Behavior positively impacted hotel Performance. These findings provide both scholars and practitioners with relevant insights into hotel innovation in Portugal.info:eu-repo/semantics/publishedVersio
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